TRAIL-induced signalling and apoptosis

scientific article

TRAIL-induced signalling and apoptosis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/S0378-4274(02)00422-8
P698PubMed publication ID12628743
P5875ResearchGate publication ID10863083

P2093author name stringMarion MacFarlane
P433issue2-3
P921main subjectCD95 death-inducing signaling complexQ14907122
TRAIL death-inducing signaling complexQ22327282
apoptotic processQ14599311
death-inducing signaling complexQ5247052
P304page(s)89-97
P577publication date2003-04-01
P1433published inToxicology LettersQ1796854
P1476titleTRAIL-induced signalling and apoptosis
P478volume139

Reverse relations

cites work (P2860)
Q36216032ABC294640, a sphingosine kinase 2 inhibitor, enhances the antitumor effects of TRAIL in non-small cell lung cancer
Q33213461Absence of gene mutation in TRAIL receptor 1 (TRAIL-R1) and TRAIL receptor 2 (TRAIL-R2) in chronic myelogenous leukemia and myelodysplastic syndrome, and analysis of mRNA Expressions of TRAIL and TRAIL-related genes in chronic myelogenous leukemia
Q35002260Anti-tumor activity of a novel protein obtained from tartary buckwheat
Q40479030Antitumor and neurotoxic effects of novel harmine derivatives and structure-activity relationship analysis.
Q37715814Apoptosis in leukemias: regulation and therapeutic targeting
Q37863133Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications
Q43273738Bortezomib sensitizes primary human esthesioneuroblastoma cells to TRAIL-induced apoptosis
Q33648419CHM-1, a new vascular targeting agent, induces apoptosis of human umbilical vein endothelial cells via p53-mediated death receptor 5 up-regulation.
Q36524672CII-DC-AdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis
Q88634204Caspase selective reagents for diagnosing apoptotic mechanisms
Q37557634Cell death pathways--potential therapeutic targets
Q43172447Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells.
Q54637021Characterization and expression analysis of TNF-related apoptosis inducing ligand (TRAIL) in grass carp Ctenopharyngodon idella.
Q45874985Co-delivery of gambogic acid and TRAIL plasmid by hyaluronic acid grafted PEI-PLGA nanoparticles for the treatment of triple negative breast cancer
Q48884086Death receptor 5 and neuroproliferation
Q93035786Death receptor 5 contributes to cardiomyocyte hypertrophy through epidermal growth factor receptor transactivation
Q37660616Death receptors: targets for cancer therapy
Q39625477Diarylheptanoid hirsutenone enhances apoptotic effect of TRAIL on epithelial ovarian carcinoma cell lines via activation of death receptor and mitochondrial pathway
Q40135330Differential effects of bexarotene on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines
Q39374254Down-regulation of Cbl-b by bufalin results in up-regulation of DR4/DR5 and sensitization of TRAIL-induced apoptosis in breast cancer cells
Q39711397Doxorubicin and etoposide sensitize small cell lung carcinoma cells expressing caspase-8 to TRAIL.
Q24793079Doxorubicin increases the effectiveness of Apo2L/TRAIL for tumor growth inhibition of prostate cancer xenografts
Q33574958EGFR inhibitors sensitize non-small cell lung cancer cells to TRAIL-induced apoptosis
Q45947203Enhancement of TRAIL cytotoxicity by AG-490 in human ALL cells is characterized by downregulation of cIAP-1 and cIAP-2 through inhibition of Jak2/Stat3.
Q33566824Enhancement of TRAIL-induced apoptosis by 5-fluorouracil requires activating Bax and p53 pathways in TRAIL-resistant lung cancers
Q35756884Epidermal growth factor and trail interactions in epithelial-derived cells.
Q40006446Erbin-regulated sensitivity of MCF-7 breast cancer cells to TRAIL via ErbB2/AKT/NF-kappaB pathway
Q35770122Expression of receptor activator of nuclear factor kappabeta ligand (RANKL) and tumour necrosis factor related, apoptosis inducing ligand (TRAIL) in breast cancer, and their relations with osteoprotegerin, oestrogen receptor, and clinicopathological
Q37096732FLIP as an anti-cancer therapeutic target
Q31120918Fas-associated protein with death domain (FADD)-independent recruitment of c-FLIPL to death receptor 5.
Q36287589Following the TRAIL from hepatitis C virus and alcohol to fatty liver
Q39177042Functional disruption of macrophage migration inhibitory factor (MIF) suppresses proliferation of human H460 lung cancer cells by caspase-dependent apoptosis
Q35613800Functions and mechanisms of action of the adenovirus E3 proteins
Q39426125Gomisin N enhances TRAIL-induced apoptosis via reactive oxygen species-mediated up-regulation of death receptors 4 and 5
Q39545932Guanylate cyclase activator YC-1 enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells via activation of apoptosis-related proteins
Q24650617HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo
Q38338065Identification of a novel mechanism of NF-kappaB inactivation by progesterone through progesterone receptors in Hec50co poorly differentiated endometrial cancer cells: induction of A20 and ABIN-2.
Q39454078Importin β1 protein-mediated nuclear localization of death receptor 5 (DR5) limits DR5/tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced cell death of human tumor cells
Q64226381Improved Anticancer Effect of Recombinant Protein izTRAIL Combined with Sorafenib and Peptide iRGD
Q45886935In vitro efficacy of AdTRAIL gene therapy of bladder cancer is enhanced by trichostatin A-mediated restoration of CAR expression and downregulation of cFLIP and Bcl-XL.
Q34803686In vivo gene delivery by embryonic-stem-cell-derived astrocytes for malignant gliomas
Q81009343Increased expression of receptor activator of NF-kappaB ligand (RANKL), its receptor RANK and its decoy receptor osteoprotegerin in the colon of Crohn's disease patients
Q40286281Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB.
Q33614335Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer
Q37745830Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis.
Q39181693Isolation, characterisation and reconstitution of cell death signalling complexes
Q38917597Loss of anchorage primarily induces non-apoptotic cell death in a human mammary epithelial cell line under atypical focal adhesion kinase signaling
Q39500273Luteolin induces apoptosis in multidrug resistant cancer cells without affecting the drug transporter function: involvement of cell line-specific apoptotic mechanisms
Q34208585Maximum growth and survival of estrogen receptor-alpha positive breast cancer cells requires the Sin3A transcriptional repressor
Q37185605Membrane expression of TRAIL receptors DR4, DR5, DcR1 and DcR2 in the normal endometrium, atypical endometrial hyperplasia and endometrioid adenocarcinoma: a tissue microarray study
Q53214880Modulation of tumor necrosis factor related apoptosis-inducing ligand (TRAIL) receptors in a human osteoclast model in vitro.
Q36041769Neural precursor cells and their role in neuro-oncology
Q38907122Notch4 Signaling Confers Susceptibility to TRAIL-Induced Apoptosis in Breast Cancer Cells
Q47620185Novel targets for sensitizing breast cancer cells to TRAIL-induced apoptosis with siRNA delivery
Q48505113Ophiopogonin B sensitizes TRAIL-induced apoptosis through activation of autophagy flux and downregulates cellular FLICE-like inhibitory protein
Q42278494Overexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL.
Q42849425Polyphenol acertannin prevents TRAIL-induced apoptosis in human keratinocytes by suppressing apoptosis-related protein activation
Q39498655Radicicol, an inhibitor of Hsp90, enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells by promoting activation of apoptosis-related proteins
Q46500389Recombinant TRAIL and TRAIL receptor analysis
Q61943533Relationship between tumour necrosis factor-related apoptosis inducing ligand (TRAIL) and vascular endothelial growth factor in human multiple myeloma patients
Q39924636Remote Limb Preconditioning Generates a Neuroprotective Effect by Modulating the Extrinsic Apoptotic Pathway and TRAIL-Receptors Expression
Q37992546Resistance to TRAIL and how to surmount it.
Q39721892Role of individual caspases induced by astrovirus on the processing of its structural protein and its release from the cell through a non-lytic mechanism.
Q28395683Salicylate-induced degeneration of cochlea spiral ganglion neurons-apoptosis signaling
Q33955186Selective BRAFV600E inhibitor PLX4720, requires TRAIL assistance to overcome oncogenic PIK3CA resistance
Q23924040Selective induction of apoptosis through the FADD/caspase-8 pathway by a p53 c-terminal peptide in human pre-malignant and malignant cells
Q45874298TRAIL and TRAIL receptors in patients with laryngeal cancer
Q37972139TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment.
Q34564468TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt.
Q64266102TRAIL, OPG, and TWEAK in kidney disease: biomarkers or therapeutic targets?
Q38652074Targeting Apoptotic Activity Against Prostate Cancer Stem Cells
Q39103044The effect of sea anemone (H. magnifica) venom on two human breast cancer lines: death by apoptosis
Q40191072The histone deacetylase inhibitors depsipeptide and MS-275, enhance TRAIL gene therapy of LNCaP prostate cancer cells without adverse effects in normal prostate epithelial cells.
Q37374435The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.
Q40617085Thiothalidomides: Novel Isosteric Analogues of Thalidomide with Enhanced TNF-α Inhibitory Activity
Q38777719Thymoquinone inhibits growth of human medulloblastoma cells by inducing oxidative stress and caspase-dependent apoptosis while suppressing NF-κB signaling and IL-8 expression.
Q33302568Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists
Q35134937Tug of war between survival and death: exploring ATM function in cancer
Q36528568Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Gene Polymorphisms and Hepatitis B Virus Infection
Q42425074Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induced mitochondrial pathway to apoptosis and caspase activation is potentiated by phospholipid scramblase-3.
Q34139591Tumor necrosis factor-related apoptosis-inducing ligand alters mitochondrial membrane lipids
Q44133700Tumor necrosis factor-related apoptosis-inducing ligand mediates the resolution of allergic airway inflammation induced by chronic allergen inhalation
Q40508879cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes
Q47805359miR-217-5p induces apoptosis by directly targeting PRKCI, BAG3, ITGAV and MAPK1 in colorectal cancer cells

Search more.