Overexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL.

scientific article published on July 2004

Overexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1027601311
P356DOI10.1038/SJ.BJC.6601910
P932PMC publication ID2364740
P698PubMed publication ID15173860
P5875ResearchGate publication ID8532693

P50authorGiuseppe GiacconeQ37829946
P2093author name stringW R Gerritsen
F A E Kruyt
D C J Mastenbroek
M A I Abou El Hassan
P2860cites workThe receptor for the cytotoxic ligand TRAILQ24310481
Identification and characterization of a new member of the TNF family that induces apoptosisQ24318423
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Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAILQ24554360
An antagonist decoy receptor and a death domain-containing receptor for TRAILQ28245153
Synergistic antitumor effect of TRAIL and doxorubicin on colon cancer cell line SW480.Q31145220
Cotreatment with STI-571 enhances tumor necrosis factor alpha-related apoptosis-inducing ligand (TRAIL or apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cellsQ32107279
Safety and antitumor activity of recombinant soluble Apo2 ligandQ33855449
Potential and caveats of TRAIL in cancer therapyQ34625563
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Current status of the molecular mechanisms of anticancer drug-induced apoptosis. The contribution of molecular-level analysis to cancer chemotherapyQ35002472
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Impact of proapoptotic proteins Bax and Bak in tumor progression and response to treatmentQ35204983
The new cardioprotector Monohydroxyethylrutoside protects against doxorubicin-induced inflammatory effects in vitroQ36670985
Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460.Q40751646
Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2- or Bcl-xL-overexpressing chemotherapy-resistant tumor cellsQ40761393
Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460.Q40832569
Adenoviral-mediated transfer of the TNF-related apoptosis-inducing ligand/Apo-2 ligand gene induces tumor cell apoptosisQ40860890
Recombinant adenovirus vectors with knobless fibers for targeted gene transferQ40906930
Defining characteristics of Types I and II apoptotic cells in response to TRAIL.Q41687820
CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c releaseQ43682296
TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applicationsQ43684721
Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL.Q43696432
Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID miceQ44183123
The protective effect of cardiac gene transfer of CuZn-sod in comparison with the cardioprotector monohydroxyethylrutoside against doxorubicin-induced cardiotoxicity in cultured cells.Q44393123
Combined TRAIL and Bax gene therapy prolonged survival in mice with ovarian cancer xenograftQ45855281
Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: characterization of in vivo efficacy, pharmacokinetics, and safetyQ46661382
Long-term tumor-free survival from treatment with the GFP-TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells.Q53950070
Adenovirus E1A oncogene expression in tumor cells enhances killing by TNF-related apoptosis-inducing ligand (TRAIL).Q54033342
Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.Q55473556
Adenovirus-TRAIL can overcome TRAIL resistance and induce a bystander effectQ63865750
Adenovirus-TRAIL can overcome TRAIL resistance and induce a bystander effectQ64377565
Targeted expression of green fluorescent protein/tumor necrosis factor-related apoptosis-inducing ligand fusion protein from human telomerase reverse transcriptase promoter elicits antitumor activity without toxic effects on primary human hepatocytesQ64378684
Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) geneQ64379934
Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cellsQ73405489
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versionsQ73704158
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligandQ73766150
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectAdenoviridaeQ193447
overexpressionQ61643320
P304page(s)171-177
P577publication date2004-07-01
P1433published inBritish Journal of CancerQ326309
P1476titleOverexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL.
P478volume91

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cites work (P2860)
Q33907576A novel cationic lipid with intrinsic antitumor activity to facilitate gene therapy of TRAIL DNA.
Q38330182Adenovirus E1B 19-kilodalton protein modulates innate immunity through apoptotic mimicry.
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Q43184280MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma
Q38120523Role of the Crosstalk between Autophagy and Apoptosis in Cancer
Q36611974Sensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations
Q36654996Structure-activity relationship studies of naphthol AS-E and its derivatives as anticancer agents by inhibiting CREB-mediated gene transcription
Q34076762Targeted knockdown of Bcl2 in tumor cells using a synthetic TRAIL 3'-UTR microRNA
Q34042769The BRG1- and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the cylindromatosis tumor suppressor gene
Q42946052The Human Lung Cancer Drug Resistance-Related Gene BC006151 Regulates Chemosensitivity in H446/CDDP Cells

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