Sensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations

scientific article published on 24 October 2006

Sensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1049702888
P356DOI10.1038/SJ.BJC.6603434
P8608Fatcat IDrelease_nd2murqkdrhsvly6hwt3is6osu
P932PMC publication ID2360594
P698PubMed publication ID17060935
P5875ResearchGate publication ID6735017

P2093author name stringP Kvasnicka
J Bodo
J Jakubikova
J Duraj
J Kasparkova
J Sedlak
L Hunakova
P2860cites workWithdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell deathQ28570235
Cisplatin: mode of cytotoxic action and molecular basis of resistanceQ29615385
Cellular processing of platinum anticancer drugsQ29617899
Phase I and pharmacological study of the farnesyltransferase inhibitor tipifarnib (Zarnestra, R115777) in combination with gemcitabine and cisplatin in patients with advanced solid tumoursQ33369069
Role of Gadd45 in apoptosisQ33800735
Regulation of the G2/M transition by p53.Q33943437
Pharmacologic interruption of the mitogen-activated extracellular-regulated kinase/mitogen-activated protein kinase signal transduction pathway: potential role in promoting cytotoxic drug actionQ34222916
p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stressQ34325063
Cisplatin: from DNA damage to cancer chemotherapy.Q34348474
Design of new anticancer therapies targeting cell cycle checkpoint pathwaysQ34416851
Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1.Q34546094
Mitogen-activated protein kinases in apoptosis regulationQ35743118
Molecular mechanisms of platinum resistance: still searching for the Achilles' heelQ35943355
Combination chemotherapy with carboplatin, capecitabine and epirubicin (ECarboX) as second- or third-line treatment in patients with relapsed ovarian cancer: a phase I/II trial.Q36613503
Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cellsQ36616527
Role of cystine transport in intracellular glutathione level and cisplatin resistance in human ovarian cancer cell linesQ36648770
Vegetables, fruit, and cancer. I. EpidemiologyQ37110546
p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cellsQ37385633
Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stressQ39528509
Sulforaphane increases the efficacy of doxorubicin in mouse fibroblasts characterized by p53 mutationsQ40255489
Inhibition of transendothelial migration and invasion of human breast cancer cells by preventing geranylgeranylation of Rho.Q40268151
Enhanced sensitivity of human ovarian carcinoma cell lines A2780 and A2780/CP to the combination of cisplatin and synthetic isothiocyanate ethyl 4-isothiocyanatobutanoate.Q40351970
Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines.Q40385121
Cytotoxicity of the organic ruthenium anticancer drug Nami-A is correlated with DNA binding in four different human tumor cell linesQ40575641
The chemopreventive agent phenethyl isothiocyanate sensitizes cells to Fas-mediated apoptosis.Q40598314
Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cellsQ40664009
XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cellsQ40816011
Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatinQ40859019
Chemoprevention by isothiocyanatesQ40933059
Cisplatin induces a persistent activation of JNK that is related to cell deathQ41062943
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.Q41120735
Effect of buthionine sulfoximine on PtII and PtIV drug accumulation and the formation of glutathione conjugates in human ovarian-carcinoma cell linesQ41514546
Overexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL.Q42278494
Validated method for the determination of the novel organo-ruthenium anticancer drug NAMI-A in human biological fluids by Zeeman atomic absorption spectrometryQ43554593
Molecular mechanisms controlling the cell cycle: fundamental aspects and implications for oncologyQ43609590
Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signaling pathway partly via enhancement of anticancer drug-induced NF kappa B activationQ43983996
Benzyl isothiocyanate inhibits excessive superoxide generation in inflammatory leukocytes: implication for prevention against inflammation-related carcinogenesisQ44701264
Histone deacetylase inhibition by valproic acid down-regulates c-FLIP/CASH and sensitizes hepatoma cells towards CD95- and TRAIL receptor-mediated apoptosis and chemotherapy.Q46835743
Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy.Q54111946
Dose-related inhibition by dietary phenethyl isothiocyanate of esophageal tumorigenesis and DNA methylation induced by N-nitrosomethylbenzylamine in ratsQ70487344
Monochlorobimane fluorometric method to measure tissue glutathioneQ73093514
Mechanism of nitric oxide-induced apoptosis in human neuroblastoma SH-SY5Y cellsQ73191402
Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cellsQ73574350
Time-dependent changes in factors involved in the apoptotic process in human ovarian cancer cells as a response to cisplatinQ77663596
P4510describes a project that usesImageJQ1659584
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)1348-1353
P577publication date2006-10-24
P1433published inBritish Journal of CancerQ326309
P1476titleSensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations
P478volume95

Reverse relations

cites work (P2860)
Q36265840Anti-proliferative activity and cell cycle arrest induced by evodiamine on paclitaxel-sensitive and -resistant human ovarian cancer cells
Q35143496Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma
Q47434492Baker's Yeast Sensitizes Metastatic Breast Cancer Cells to Paclitaxel In Vitro
Q39462960Cytotoxic properties of Adamantyl isothiocyanate and potential in vivo metabolite adamantyl-N-acetylcystein in gynecological cancer cells
Q39496590Description of the cytotoxic effect of a novel drug Abietyl-Isothiocyanate on endometrial cancer cell lines
Q64111721Genotoxic Effects of Tributyltin and Triphenyltin Isothiocyanates, Cognate RXR Ligands: Comparison in Human Breast Carcinoma MCF 7 and MDA-MB-231 Cells
Q53550376Isothiocyanate E-4IB induces MAPK activation, delayed cell cycle transition and apoptosis.
Q37010601Isothiocyanate NB7M causes selective cytotoxicity, pro-apoptotic signalling and cell-cycle regression in ovarian cancer cells
Q34214923Lipoplatin formulation review article
Q90522692Pharmacological Inhibition of p38 MAPK by SB203580 Increases Resistance to Carboplatin in A2780cp Cells and Promotes Growth in Primary Ovarian Cancer Cells
Q34076604Sensitization of non-small cell lung cancer cells to cisplatin by naturally occurring isothiocyanates
Q33728766Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells
Q36057163Synergistic effect of allyl isothiocyanate (AITC) on cisplatin efficacy in vitro and in vivo.

Search more.