scholarly article | Q13442814 |
P2093 | author name string | Harris LA | |
Xie D | |||
Fox JA | |||
Totpal K | |||
Kelley SK | |||
Deforge L | |||
Bussiere J | |||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | apoptotic process | Q14599311 |
pharmacokinetics | Q323936 | ||
P304 | page(s) | 31-38 | |
P577 | publication date | 2001-10-01 | |
P1433 | published in | Journal of Pharmacology and Experimental Therapeutics | Q1500272 |
P1476 | title | Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: characterization of in vivo efficacy, pharmacokinetics, and safety | |
P478 | volume | 299 |
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Q34384021 | Advances in Viral Vector-Based TRAIL Gene Therapy for Cancer |
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Q33658976 | Antitumor Activity of a Mesenchymal Stem Cell Line Stably Secreting a Tumor-Targeted TNF-Related Apoptosis-Inducing Ligand Fusion Protein |
Q39874761 | Apo2L/TRAIL inhibits tumor growth and bone destruction in a murine model of multiple myeloma |
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Q37073330 | Colony-Stimulating Factor 1 Receptor Antagonists Sensitize Human Immunodeficiency Virus Type 1-Infected Macrophages to TRAIL-Mediated Killing |
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Q36134152 | Hetero-modification of TRAIL trimer for improved drug delivery and in vivo antitumor activities |
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Q36777316 | Improved antitumor activity and tumor targeting of NH(2)-terminal-specific PEGylated tumor necrosis factor-related apoptosis-inducing ligand |
Q37657813 | Improved antitumor activity of TRAIL fusion protein via formation of self-assembling nanoparticle |
Q41483641 | Improvement of Pharmacokinetic Profile of TRAIL via Trimer-Tag Enhances its Antitumor Activity in vivo |
Q59224646 | In vivo anti-lymphoma activity of an agonistic human recombinant anti-TRAIL-R2 minibody |
Q34803686 | In vivo gene delivery by embryonic-stem-cell-derived astrocytes for malignant gliomas |
Q36366424 | Intracellular-signaling tumor-regression modeling of the pro-apoptotic receptor agonists dulanermin and conatumumab |
Q35863285 | Kinetics in signal transduction pathways involving promiscuous oligomerizing receptors can be determined by receptor specificity: apoptosis induction by TRAIL. |
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Q38697040 | ML327 induces apoptosis and sensitizes Ewing sarcoma cells to TNF-related apoptosis-inducing ligand |
Q38115574 | Manipulating the apoptotic pathway: potential therapeutics for cancer patients |
Q57174410 | Mesenchymal Stem Cell Expressing TRAIL as Targeted Therapy against Sensitised Tumour |
Q39297108 | Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: evidence for the role of c-Jun N-terminal kinase activation. |
Q37517140 | Mix to validate: a facile, reversible PEGylation for fast screening of potential therapeutic proteins in vivo |
Q33805582 | Modulation of TRAIL resistance in colon carcinoma cells: different contributions of DR4 and DR5. |
Q91716512 | Molecular Mode of Action of TRAIL Receptor Agonists-Common Principles and Their Translational Exploitation |
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Q38931192 | Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction |
Q37473651 | Nanoparticle engineered TRAIL-overexpressing adipose-derived stem cells target and eradicate glioblastoma via intracranial delivery |
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Q36608654 | Newly established tumourigenic primary human colon cancer cell lines are sensitive to TRAIL-induced apoptosis in vitro and in vivo |
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Q35555592 | Soluble TRAIL concentrations are raised in patients with systemic lupus erythematosus. |
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Q34291312 | TRAIL in cancer therapy: present and future challenges |
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Q35770748 | TRAIL protein expression in breast cancer cells correlates with nuclear grade |
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Q34383454 | TRAIL treatment provokes mutations in surviving cells |
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Q37889112 | TRAIL-mediated signaling in prostate, bladder and renal cancer |
Q37012681 | TRAIL-receptor 1 IgM antibodies strongly induce apoptosis in human cancer cells in vitro and in vivo |
Q39056037 | Targeted induction of apoptosis in glioblastoma multiforme cells by an MRP3-specific TRAIL fusion protein in vitro |
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Q35172090 | The Biology of TRAIL and the Role of TRAIL-Based Therapeutics in Infectious Diseases |
Q36511919 | The TRAIL to targeted therapy of breast cancer |
Q36312145 | The inhibitory effect of MSCs expressing TRAIL as a cellular delivery vehicle in combination with cisplatin on hepatocellular carcinoma |
Q36792997 | The promise of TRAIL--potential and risks of a novel anticancer therapy |
Q36733723 | The role of the mitochondria in mediating cytotoxicity of anti-cancer therapies |
Q36742314 | The synergistic apoptotic interaction of Indole-3-Carbinol and Genistein with TRAIL on endometrial cancer cells |
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Q36836285 | Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia-Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide-Dependent Mechanisms |
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Q36218165 | Tumor priming by Apo2L/TRAIL reduces interstitial fluid pressure and enhances efficacy of liposomal gemcitabine in a patient derived xenograft tumor model |
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Q38998166 | Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets. |
Q37424066 | Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice. |
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