Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma

scientific article published on 16 January 2014

Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.5966/SCTM.2013-0132
P8608Fatcat IDrelease_smwuqw7rpraidjbqytlyan56fe
P932PMC publication ID3925057
P698PubMed publication ID24436439

P2093author name stringSin-Soo Jeun
Chang Hyun Jeong
Chung Heon Ryu
Seong Muk Kim
Jae-Deog Jang
Ji Sun Woo
P2860cites workIrradiation Enhances the Tumor Tropism and Therapeutic Potential of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Secreting Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Glioma TherapyQ39644411
TRAIL-induced apoptosis is preferentially mediated via TRAIL receptor 1 in pancreatic carcinoma cells and profoundly enhanced by XIAP inhibitorsQ39645187
Targeting of XIAP combined with systemic mesenchymal stem cell-mediated delivery of sTRAIL ligand inhibits metastatic growth of pancreatic carcinoma cellsQ39649739
Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial gliomaQ39910399
Mechanisms of resistance of human glioma cells to Apo2 ligand/TNF-related apoptosis-inducing ligandQ40114772
Cancer gene therapy using a novel secretable trimeric TRAIL.Q40367155
Convection-enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in an intracranial glioblastoma xenograft modelQ40508031
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.Q40975748
Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cellsQ42874678
Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapyQ43100976
Complete regression of metastatic renal cell carcinoma by multiple injections of engineered mesenchymal stem cells expressing dodecameric TRAIL and HSV-TK.Q45883468
Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: characterization of in vivo efficacy, pharmacokinetics, and safetyQ46661382
Phase 1b Study of Dulanermin (recombinant human Apo2L/TRAIL) in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Patients With Advanced Non-Squamous Non–Small-Cell Lung CancerQ60620763
Barriers to effective TRAIL-targeted therapy of malignancyQ81375289
A phase I safety and pharmacokinetic study of the death receptor 5 agonistic antibody PRO95780 in patients with advanced malignanciesQ82847250
Inhibition of death receptor signals by cellular FLIPQ24316446
Identification and characterization of a new member of the TNF family that induces apoptosisQ24318423
X-linked IAP is a direct inhibitor of cell-death proteasesQ24318710
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastomaQ27860910
Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomideQ33341259
Safety and antitumor activity of recombinant soluble Apo2 ligandQ33855449
Enhanced proapoptotic effects of tumor necrosis factor-related apoptosis-inducing ligand on temozolomide-resistant glioma cellsQ34618860
TRAIL receptor signalling and modulation: Are we on the right TRAIL?Q34913133
RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivoQ35225270
Cisplatin restores TRAIL apoptotic pathway in glioblastoma-derived stem cells through up-regulation of DR5 and down-regulation of c-FLIP.Q35665706
Mechanisms of resistance to TRAIL-induced apoptosis in cancerQ35954258
Mesenchymal stem cells (MSC) as therapeutic cytoreagents for gene therapy.Q36072501
Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosisQ36084509
Genetic strategies for brain tumor therapyQ36247099
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapyQ37140126
Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL).Q37221909
TRAIL gene therapy: from preclinical development to clinical applicationQ37307340
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and TemozolomideQ37356520
Review: on TRAIL for malignant glioma therapy?Q37681647
Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapyQ39245228
Effective combination therapy for malignant glioma with TRAIL-secreting mesenchymal stem cells and lipoxygenase inhibitor MK886.Q39282411
CXC chemokine receptor 1 enhances the ability of human umbilical cord blood-derived mesenchymal stem cells to migrate toward gliomasQ39570178
A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma modelsQ39630653
P433issue2
P921main subjectgene therapyQ213901
temozolomideQ425088
mesenchymal stem cellQ1922379
P304page(s)172-182
P577publication date2014-01-16
P1433published inStem Cells Translational MedicineQ26842216
P1476titlePotential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma
P478volume3

Reverse relations

cites work (P2860)
Q38227489Advances in stem cells, induced pluripotent stem cells, and engineered cells: delivery vehicles for anti-glioma therapy
Q41983273Clinical and prognostic significance of high-mobility group box-1 in human gliomas
Q39556636Combined treatment, based on lysomustine administration with mesenchymal stem cells expressing cytosine deaminase therapy, leads to pronounced murine Lewis lung carcinoma growth inhibition
Q33757933Conditioned media from human adipose tissue-derived mesenchymal stem cells and umbilical cord-derived mesenchymal stem cells efficiently induced the apoptosis and differentiation in human glioma cell lines in vitro
Q27026414Engineering mesenchymal stem cells for regenerative medicine and drug delivery
Q41709256Human menstrual blood-derived mesenchymal stem cells as a cellular vehicle for malignant glioma gene therapy
Q36402844In vivo near-infrared imaging for the tracking of systemically delivered mesenchymal stem cells: tropism for brain tumors and biodistribution
Q64277474Magnetic ternary nanohybrids for nonviral gene delivery of stem cells and applications on cancer therapy
Q57174410Mesenchymal Stem Cell Expressing TRAIL as Targeted Therapy against Sensitised Tumour
Q47109590Mesenchymal stem cells as therapeutic agents and in gene delivery for the treatment of glioma*.
Q53269695Neural differentiation of mesenchymal stem cells influences their chemotactic responses to stromal cell-derived factor-1α.
Q39725955Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival
Q37641600Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide
Q58805856Renal Ischemia-Reperfusion Injury in a Diabetic Monkey Model and Therapeutic Testing of Human Bone Marrow-Derived Mesenchymal Stem Cells
Q28076798Role of nanotechnology and gene delivery systems in TRAIL-based therapies
Q38521752Stem cell in alternative treatments for brain tumors: potential for gene delivery
Q38245163Stem cell-based therapies for cancer treatment: separating hope from hype
Q38855638Stem cell-based therapies for tumors in the brain: are we there yet?
Q47142453Stem cells in cancer therapy: opportunities and challenges
Q59807366Sulforaphane from Cruciferous Vegetables: Recent Advances to Improve Glioblastoma Treatment
Q42479312Temozolomide sensitizes stem-like cells of glioma spheres to TRAIL-induced apoptosis via upregulation of casitas B-lineage lymphoma (c-Cbl) protein
Q38213836Therapeutic cell carriers: a potential road to cure glioma
Q42368100pIL6-TRAIL-engineered umbilical cord mesenchymal/stromal stem cells are highly cytotoxic for myeloma cells both in vitro and in vivo

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