A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy.

scientific article

A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/STEM.313
P932PMC publication ID3021283
P698PubMed publication ID20127797
P5875ResearchGate publication ID41402789

P50authorRalph WeisslederQ7288259
Jeroen van de WaterQ82762037
Randa KasmiehQ125261420
P2093author name stringKhalid Shah
Shawn D Hingtgen
P2860cites workIdentification and characterization of a new member of the TNF family that induces apoptosisQ24318423
The leading edge of stem cell therapeuticsQ28273636
Tumor therapy mediated by lentiviral expression of shBcl-2 and S-TRAIL.Q35812718
Neural precursor cells and their role in neuro-oncologyQ36041769
Neural stem cells as novel cancer therapeutic vehiclesQ36477288
The promise of TRAIL--potential and risks of a novel anticancer therapyQ36792997
Stem and progenitor cell-mediated tumor selective gene therapyQ37120161
Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfareQ37122166
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapyQ37140126
Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL).Q37221909
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and TemozolomideQ37356520
Optical and multimodality molecular imaging: insights into atherosclerosisQ37440343
Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapyQ39245228
Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma modelQ39988659
MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomasQ40073679
Fusion of Gaussia luciferase to an engineered anti-carcinoembryonic antigen (CEA) antibody for in vivo optical imagingQ40118072
Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumorsQ40249070
Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in established and primary glioma cell linesQ40432328
Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression.Q40476541
Exceptionally potent anti-tumor bystander activity of an scFv:sTRAIL fusion protein with specificity for EGP2 toward target antigen-negative tumor cellsQ40490888
Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living miceQ40662328
Adenoviral-mediated transfer of the TNF-related apoptosis-inducing ligand/Apo-2 ligand gene induces tumor cell apoptosisQ40860890
Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo.Q43713225
Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapyQ44198636
Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivoQ44611172
Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: characterization of in vivo efficacy, pharmacokinetics, and safetyQ46661382
Prospects for stem cell-based therapyQ47893771
Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell.Q49011276
Construction and characterization of two versions of bifunctional EGFP-sTRAIL fusion proteins.Q50677686
In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis.Q55471304
Applications and limitations of interspecies scaling and in vitro extrapolation in pharmacokineticsQ77710566
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)832-841
P577publication date2010-04-01
P1433published inStem CellsQ15724411
P1476titleA novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy
P478volume28

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cites work (P2860)
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Q30843565Electrospun nanofibrous scaffolds increase the efficacy of stem cell-mediated therapy of surgically resected glioblastoma
Q36695971Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas
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Q36684365Fibrin matrices enhance the transplant and efficacy of cytotoxic stem cell therapy for post-surgical cancer.
Q94660275Generation and Profiling of Tumor-Homing Induced Neural Stem Cells from the Skin of Cancer Patients
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Q33704489Neural stem cell therapy for cancer
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Q47901080Space Invaders: Brain Tumor Exploitation of the Stem Cell Niche
Q37433463TRAIL on trial: preclinical advances in cancer therapy
Q36339837Therapeutic stem cells expressing variants of EGFR-specific nanobodies have antitumor effects.
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