Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas

scientific article published on 25 December 2011

Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NN.3019
P932PMC publication ID3601490
P698PubMed publication ID22197831
P5875ResearchGate publication ID51923635

P2093author name stringKhalid Shah
Jose-Luiz Figueiredo
Shawn Hingtgen
Timo M Kauer
P2860cites workAPO2 ligand: a novel lethal weapon against malignant glioma?Q28272697
A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy.Q39744489
Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2.Q39853842
Anti-proliferative effect of the gastrin-release peptide receptor antagonist RC-3095 plus temozolomide in experimental glioblastoma models.Q39897760
Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma modelQ39988659
Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFRQ40619097
Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical modelQ42573981
Outcome of newly diagnosed glioblastoma patients treated by radiotherapy plus concomitant and adjuvant temozolomide: a long-term analysis.Q45798961
Human adipose tissue-derived mesenchymal stem cells: characteristics and therapeutic potential as cellular vehicles for prodrug gene therapy against brainstem gliomasQ45870836
Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resectionQ46065962
Induction of glioblastoma apoptosis using neural stem cell-mediated delivery of tumor necrosis factor-related apoptosis-inducing ligandQ46324484
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients.Q46771343
Viability and differentiation of neural precursors on hyaluronic acid hydrogel scaffoldQ48568413
Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis.Q50524244
The risk of putting something where it does not belong: mesenchymal stem cells produce masses in the brainQ83656011
Death receptors: signaling and modulationQ28280897
CNS stem and progenitor cell differentiation into functional neuronal circuits in three-dimensional collagen gelsQ28292053
Mesenchymal stem cells within tumour stroma promote breast cancer metastasisQ29614303
Malignant gliomas in adultsQ29615708
Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cellsQ30476168
Advances in brain tumor surgeryQ31134396
Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapyQ33465104
mTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cellsQ34097241
The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissueQ34154476
A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR.Q34312127
Apoptosis in human glioblastoma cells produced using embryonic stem cell-derived astrocytes expressing tumor necrosis factor-related apoptosis-inducing ligandQ34551591
Ectopic expression of the sodium-iodide symporter enables imaging of transplanted cardiac stem cells in vivo by single-photon emission computed tomography or positron emission tomographyQ34657611
Therapeutic effect of neural stem cells expressing TRAIL and bortezomib in mice with glioma xenograftsQ35175677
Tumor therapy mediated by lentiviral expression of shBcl-2 and S-TRAIL.Q35812718
Mesenchymal stem cells engineered for cancer therapyQ36092724
Chemotherapy delivery issues in central nervous system malignancy: a reality check.Q36835363
Mesenchymal stem cells in cancer: tumor-associated fibroblasts and cell-based delivery vehiclesQ36901346
Biomimetic material systems for neural progenitor cell-based therapyQ36991941
Cell delivery mechanisms for tissue repairQ37121094
Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfareQ37122166
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapyQ37140126
Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumorsQ37346039
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and TemozolomideQ37356520
Evaluating dual activity LPA receptor pan-antagonist/autotaxin inhibitors as anti-cancer agents in vivo using engineered human tumorsQ37372468
Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectorsQ37447217
Glioblastoma multiforme: a review of where we have been and where we are goingQ37530934
Biomaterials for promoting brain protection, repair and regeneration.Q37572357
Induced pluripotent stem cells: a new revolution for clinical neurology?Q37857439
Modulation of CCAAT/enhancer binding protein homologous protein (CHOP)-dependent DR5 expression by nelfinavir sensitizes glioblastoma multiforme cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).Q38673432
Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapyQ39245228
Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressionsQ39569903
A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma modelsQ39630653
Irradiation Enhances the Tumor Tropism and Therapeutic Potential of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Secreting Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Glioma TherapyQ39644411
Cisplatin-enhanced sensitivity of glioblastoma multiforme U251 cells to adenovirus-delivered TRAIL in vitroQ39681548
Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors.Q39725116
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcell deathQ2383867
P304page(s)197-204
P577publication date2011-12-25
P1433published inNature NeuroscienceQ1535359
P1476titleEncapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas
P478volume15

Reverse relations

cites work (P2860)
Q38635798A 3D-Engineered Conformal Implant Releases DNA Nanocomplexs for Eradicating the Postsurgery Residual Glioblastoma
Q44548491A microgel construction kit for bioorthogonal encapsulation and pH-controlled release of living cells
Q38308868Advances in cell encapsulation technology and its application in drug delivery
Q38227489Advances in stem cells, induced pluripotent stem cells, and engineered cells: delivery vehicles for anti-glioma therapy
Q58223823Application of Millifluidics to Encapsulate and Support Viable Human Mesenchymal Stem Cells in a Polysaccharide Hydrogel
Q36176880B(12)-mediated, long wavelength photopolymerization of hydrogels.
Q30724766BAFF, APRIL, TWEAK, BCMA, TACI and Fn14 proteins are related to human glioma tumor grade: immunohistochemistry and public microarray data meta-analysis
Q33753135Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumors
Q30614247Biopolymer implants enhance the efficacy of adoptive T-cell therapy.
Q90405817Cancer in a dish: progress using stem cells as a platform for cancer research
Q38960128Combination of systemic chemotherapy with local stem cell delivered S-TRAIL in resected brain tumors
Q58724855Concise Review: Neural Stem Cell-Mediated Targeted Cancer Therapies
Q27327216Detection of human brain cancer infiltration ex vivo and in vivo using quantitative optical coherence tomography
Q89936443Developing Implantable Scaffolds to Enhance Neural Stem Cell Therapy for Post-Operative Glioblastoma
Q83288373Drug delivery: Encapsulation improves therapeutic stem cell action
Q56992592Ein Mikrogelbaukasten für die bioorthogonale Verkapselung und pH-gesteuerte Freisetzung von lebenden Zellen
Q30843565Electrospun nanofibrous scaffolds increase the efficacy of stem cell-mediated therapy of surgically resected glioblastoma
Q47214779Encapsulated Optically Responsive Cell Systems: Toward Smart Implants in Biomedicine.
Q38090923Encapsulated stem cells for cancer therapy
Q38944271Encapsulated stem cells loaded with hyaluronidase-expressing oncolytic virus for brain tumor therapy.
Q34444939Engineering toxin-resistant therapeutic stem cells to treat brain tumors
Q92349932Established and Emerging Strategies for Drug Delivery Across the Blood-Brain Barrier in Brain Cancer
Q64105995Exploiting tumor-intrinsic signals to induce mesenchymal stem cell-mediated suicide gene therapy to fight malignant glioma
Q36684365Fibrin matrices enhance the transplant and efficacy of cytotoxic stem cell therapy for post-surgical cancer.
Q67201058Gene editing for immune cell therapies
Q94660275Generation and Profiling of Tumor-Homing Induced Neural Stem Cells from the Skin of Cancer Patients
Q39310030Generation and manipulation of hydrogel microcapsules by droplet-based microfluidics for mammalian cell culture
Q38790593Genetic engineering of platelets to neutralize circulating tumor cells
Q90449437Hyaluronic acid based low viscosity hydrogel as a novel carrier for Convection Enhanced Delivery of CAR T cells
Q90608879Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
Q57297372In situ administration of cytokine combinations induces tumor regression in mice
Q37022290Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo
Q57640952Intra-cavity stem cell therapy inhibits tumor progression in a novel murine model of medulloblastoma surgical resection
Q64277474Magnetic ternary nanohybrids for nonviral gene delivery of stem cells and applications on cancer therapy
Q55456721Mechanisms of enhanced antiglioma efficacy of polysorbate 80-modified paclitaxel-loaded PLGA nanoparticles by focused ultrasound.
Q34647951Mesenchymal stem cells derived from adipose tissue vs bone marrow: in vitro comparison of their tropism towards gliomas
Q38715077Mesenchymal stromal cells for the delivery of oncolytic viruses in gliomas
Q57372236Microfluidic-Based Synthesis of Hydrogel Particles for Cell Microencapsulation and Cell-Based Drug Delivery
Q26999345Molecular mechanism underlying lymphatic metastasis in pancreatic cancer
Q37473651Nanoparticle engineered TRAIL-overexpressing adipose-derived stem cells target and eradicate glioblastoma via intracranial delivery
Q33704489Neural stem cell therapy for cancer
Q92099101Oncolytic viruses: overcoming translational challenges
Q90419003Patient-Derived Glioma Models: From Patients to Dish to Animals
Q38764607Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model.
Q36543537Real-time multi-modality imaging of glioblastoma tumor resection and recurrence.
Q89976335Recent Progress of Stem Cell Therapy in Cancer Treatment: Molecular Mechanisms and Potential Applications
Q38133954Regenerative therapies for central nervous system diseases: a biomaterials approach
Q33620254Regulation of gap junction channels by infectious agents and inflammation in the CNS.
Q58803096Reprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors
Q26775038Stem Cell-Based Cell Carrier for Targeted Oncolytic Virotherapy: Translational Opportunity and Open Questions
Q38245163Stem cell-based therapies for cancer treatment: separating hope from hype
Q38855638Stem cell-based therapies for tumors in the brain: are we there yet?
Q47142453Stem cells in cancer therapy: opportunities and challenges
Q42218017Stem cells loaded with multimechanistic oncolytic herpes simplex virus variants for brain tumor therapy.
Q90361854Stem cells: a promising candidate to treat neurological disorders
Q37707063Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy
Q48225985Sustained Delivery of Doxorubicin via Acetalated Dextran Scaffold Prevents Glioblastoma Recurrence after Surgical Resection.
Q37433463TRAIL on trial: preclinical advances in cancer therapy
Q54438434Targeting Tumor Hypoxia Using Nanoparticle-engineered CXCR4-overexpressing Adipose-derived Stem Cells.
Q35974503Targeting breast to brain metastatic tumours with death receptor ligand expressing therapeutic stem cells
Q35153149Targeting c-Met receptor overcomes TRAIL-resistance in brain tumors
Q37109638The homing and inhibiting effects of hNSCs-BMP4 on human glioma stem cells
Q92003487Theranostic OCT microneedle for fast ultrahigh-resolution deep-brain imaging and efficient laser ablation in vivo
Q49936618Therapeutic Neural Stem Cells Engineered During Different Stages of Reprogramming Reveal Varying Therapeutic Efficacies
Q38213836Therapeutic cell carriers: a potential road to cure glioma
Q39198277Therapeutic efficacy and fate of bimodal engineered stem cells in malignant brain tumors
Q36339837Therapeutic stem cells expressing variants of EGFR-specific nanobodies have antitumor effects.
Q27333831Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma.
Q50083504Tumor Resection Recruits Effector T Cells and Boosts Therapeutic Efficacy of Encapsulated Stem Cells Expressing IFNβ in Glioblastomas.
Q48329121Tumor-homing cytotoxic human induced neural stem cells for cancer therapy.
Q38730790Use of genetically engineered stem cells for glioma therapy
Q52872887Visualization of real-time degradation of pH-responsive polyglycerol nanogels via atomic force microscopy.
Q41920847microRNA-7 upregulates death receptor 5 and primes resistant brain tumors to caspase-mediated apoptosis

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