Engineering toxin-resistant therapeutic stem cells to treat brain tumors

scientific article

Engineering toxin-resistant therapeutic stem cells to treat brain tumors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/STEM.1874
P932PMC publication ID4305025
P698PubMed publication ID25346520
P5875ResearchGate publication ID267324890

P2093author name stringBenjamin E Rich
Khalid Shah
Daniel W Stuckey
Nihal Karakas
Shawn D Hingtgen
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Phase II trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with hairy cell leukemiaQ37242280
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A recombinant form of Pseudomonas exotoxin directed at the epidermal growth factor receptor that is cytotoxic without requiring proteolytic processingQ38326533
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Bioactive IL7-diphtheria fusion toxin secreted by mammalian cellsQ40442648
Diphtheria Toxin−Epidermal Growth Factor Fusion Protein and Pseudomonas Exotoxin−Interleukin 13 Fusion Protein Exert Synergistic Toxicity against Human Glioblastoma Multiforme CellsQ40615599
Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignanciesQ40623388
Molecular expression analysis of restrictive receptor for interleukin 13, a brain tumor-associated cancer/testis antigen.Q40860001
Establishment and properties of a growth factor-dependent, perpetual neural stem cell line from the human CNS.Q40899057
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Interleukin-13 sensitivity and receptor phenotypes of human glial cell lines: non-neoplastic glia and low-grade astrocytoma differ from malignant gliomaQ42631907
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Interleukin-13 receptor as a unique target for anti-glioblastoma therapyQ43567315
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Interleukin-13 receptor alpha 2, EphA2, and Fos-related antigen 1 as molecular denominators of high-grade astrocytomas and specific targets for combinatorial therapyQ46825509
Mutations in the elongation factor 2 gene which confer resistance to diphtheria toxin and Pseudomonas exotoxin A. Genetic and biochemical analysesQ48070476
Suppression of malignant glioma recurrence in a newly developed animal model by endogenous inhibitorsQ48447313
Expression of a restrictive receptor for interleukin 13 is associated with glial transformation.Q53403935
Highly frequent single amino acid substitution in mammalian elongation factor 2 (EF-2) results in expression of resistance to EF-2-ADP-ribosylating toxins.Q54400378
Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli.Q54768075
Human glioma cells overexpress receptors for interleukin 13 and are extremely sensitive to a novel chimeric protein composed of interleukin 13 and pseudomonas exotoxin.Q55480258
One molecule of diphtheria toxin fragment A introduced into a cell can kill the cellQ67390807
A novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin is highly cytotoxic to human carcinoma cells expressing receptors for interleukin 13 and interleukin 4Q71921204
Responses in refractory hairy cell leukemia to a recombinant immunotoxinQ73160386
Phase I trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with B-cell malignanciesQ80977096
P4510describes a project that usesImageJQ1659584
P433issue2
P921main subjectbrain tumorQ233309
P304page(s)589-600
P577publication date2015-02-01
P1433published inStem CellsQ15724411
P1476titleEngineering toxin-resistant therapeutic stem cells to treat brain tumors
P478volume33

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cites work (P2860)
Q38944271Encapsulated stem cells loaded with hyaluronidase-expressing oncolytic virus for brain tumor therapy.
Q57640952Intra-cavity stem cell therapy inhibits tumor progression in a novel murine model of medulloblastoma surgical resection
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Q45858463Mesenchymal stem cell: a new horizon in cancer gene therapy
Q38627347Multifunctional receptor-targeting antibodies for cancer therapy
Q33704489Neural stem cell therapy for cancer
Q38855638Stem cell-based therapies for tumors in the brain: are we there yet?
Q39285733Therapeutic application of multipotent stem cells
Q48275610Toxin-secreting implantable therapeutic stem cells
Q50083504Tumor Resection Recruits Effector T Cells and Boosts Therapeutic Efficacy of Encapsulated Stem Cells Expressing IFNβ in Glioblastomas.
Q37589818Vitamin B12: a tunable, long wavelength, light-responsive platform for launching therapeutic agents

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