Targeting c-Met receptor overcomes TRAIL-resistance in brain tumors

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Targeting c-Met receptor overcomes TRAIL-resistance in brain tumors is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...995490D
P356DOI10.1371/JOURNAL.PONE.0095490
P932PMC publication ID3991662
P698PubMed publication ID24748276
P5875ResearchGate publication ID261762444

P2093author name stringKhalid Shah
Wanlu Du
Liubov Uslar
Sindhura Sevala
P2860cites workMet signals hepatocyte survival by preventing Fas-triggered FLIP degradation in a PI3k-Akt-dependent manner.Q51987719
cMet and Fas receptor interaction inhibits death-inducing signaling complex formation in endothelial cells.Q53855934
How TRAIL kills cancer cells, but not normal cellsQ73632146
TRAIL: a molecule with multiple receptors and control mechanismsQ77485552
The receptor for the cytotoxic ligand TRAILQ24310481
Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene ProductQ24310794
Identification and characterization of a new member of the TNF family that induces apoptosisQ24318423
Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesisQ24683896
TRAIL receptor-2 signals apoptosis through FADD and caspase-8Q28142998
Met, metastasis, motility and moreQ28235183
An antagonist decoy receptor and a death domain-containing receptor for TRAILQ28245153
The TRAIL to selective tumor deathQ28504568
Hepatocyte growth factor enhances death receptor-induced apoptosis by up-regulating DR5Q30851343
Evaluating the effect of therapeutic stem cells on TRAIL resistant and sensitive medulloblastomasQ34474267
Tumor therapy mediated by lentiviral expression of shBcl-2 and S-TRAIL.Q35812718
c-Met inhibitor synergizes with tumor necrosis factor-related apoptosis-induced ligand to induce papillary thyroid carcinoma cell deathQ35872516
Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomasQ36695971
The promise of TRAIL--potential and risks of a novel anticancer therapyQ36792997
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapyQ37140126
TRAIL on trial: preclinical advances in cancer therapyQ37433463
Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectorsQ37447217
Receptor tyrosine kinases: principles and functions in glioma invasion.Q38033495
Targeting c-MET in the battle against advanced nonsmall-cell lung cancerQ38079495
Therapeutic efficacy and fate of bimodal engineered stem cells in malignant brain tumorsQ39198277
Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial gliomaQ39910399
Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma modelQ39988659
Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression.Q40476541
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.Q40975748
A mechanism of cell survival: sequestration of Fas by the HGF receptor Met.Q43894879
Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapyQ44198636
Molecular cloning of a new transforming gene from a chemically transformed human cell line.Q45345810
In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosisQ48700301
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectbrain tumorQ233309
P304page(s)e95490
P577publication date2014-04-18
P1433published inPLOS OneQ564954
P1476titleTargeting c-Met receptor overcomes TRAIL-resistance in brain tumors
P478volume9