| Q41122658 | A CRISPR Resource for Individual, Combinatorial, or Multiplexed Gene Knockout |
| Q37508613 | A CRISPR/Cas9 Functional Screen Identifies Rare Tumor Suppressors |
| Q91106503 | A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer |
| Q36591466 | A Modular Assembly Platform for Rapid Generation of DNA Constructs. |
| Q33793854 | A Pipeline for Drug Target Identification and Validation |
| Q48544889 | A TFIID-SAGA Perturbation that Targets MYB and Suppresses Acute Myeloid Leukemia. |
| Q37080881 | A combinatorial strategy for treating KRAS-mutant lung cancer |
| Q38936797 | A computational algorithm to predict shRNA potency. |
| Q36100164 | A let-7-to-miR-125 MicroRNA Switch Regulates Neuronal Integrity and Lifespan in Drosophila |
| Q37488746 | A modular and flexible ESC-based mouse model of pancreatic cancer. |
| Q89589492 | A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo |
| Q28258154 | A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and down-regulation |
| Q37047996 | A pipeline for the generation of shRNA transgenic mice |
| Q34137070 | A primer on using pooled shRNA libraries for functional genomic screens |
| Q35627849 | A rapid and scalable system for studying gene function in mice using conditional RNA interference |
| Q36394282 | A systematic evaluation of nucleotide properties for CRISPR sgRNA design. |
| Q34581520 | A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility |
| Q37547028 | A versatile RNA vector for delivery of coding and noncoding RNAs. |
| Q33914682 | Accelerating cancer modeling with RNAi and nongermline genetically engineered mouse models |
| Q26852489 | Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference |
| Q35910008 | Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys |
| Q35050602 | An RNAi-based approach to down-regulate a gene family in vivo |
| Q44620413 | An in vivo transfection system for inducible gene expression and gene silencing in murine hepatocytes |
| Q35237394 | An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance |
| Q34328115 | Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing. |
| Q60915920 | CRISPR-Cas9 a boon or bane: the bumpy road ahead to cancer therapeutics |
| Q24625361 | CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes |
| Q47129165 | CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level. |
| Q33772342 | CRISPR/Cas9: From Genome Engineering to Cancer Drug Discovery |
| Q33922903 | CRISPulator: a discrete simulation tool for pooled genetic screens |
| Q112724548 | Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage |
| Q36439726 | Cell-based genomic screening: elucidating virus-host interactions |
| Q50795989 | Construction of Modular Lentiviral Vectors for Effective Gene Expression and Knockdown. |
| Q50138597 | DISE: A Seed-Dependent RNAi Off-Target Effect That Kills Cancer Cells. |
| Q39357612 | Development of a siRNA and shRNA screening system based on a kinase fusion protein |
| Q34287993 | Development of siRNA payloads to target KRAS-mutant cancer |
| Q49997178 | Differential Effector Engagement by Oncogenic KRAS. |
| Q24294914 | Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors |
| Q92132950 | Distinct Colorectal Cancer-Associated APC Mutations Dictate Response to Tankyrase Inhibition |
| Q35534393 | Drosha processing controls the specificity and efficiency of global microRNA expression |
| Q39381450 | Effects of STAT3 gene silencing and rapamycin on apoptosis in hepatocarcinoma cells |
| Q90290413 | Elevated Oxidative Stress Impairs Hematopoietic Progenitor Function in C57BL/6 Substrains |
| Q48209699 | Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map. |
| Q39181191 | Forward and reverse genetics through derivation of haploid mouse embryonic stem cells. |
| Q47445570 | From cancer genomes to oncogenic drivers, tumour dependencies and therapeutic targets |
| Q38061354 | Functional genomic screening to enhance oncolytic virotherapy |
| Q35907945 | Functional parameters of Dicer-independent microRNA biogenesis |
| Q36745020 | Functional screen identifies regulators of murine hematopoietic stem cell repopulation |
| Q60302654 | Genetically modified pigs are protected from classical swine fever virus |
| Q90437192 | Global regulation of the histone mark H3K36me2 underlies epithelial plasticity and metastatic progression |
| Q36354259 | HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers |
| Q34054107 | High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing |
| Q90407386 | Identification of the targets of T cell receptor therapeutic agents and cells by use of a high throughput genetic platform |
| Q35164201 | Immunodeficiency and autoimmune enterocolopathy linked to NFAT5 haploinsufficiency |
| Q38243939 | Impact of RNA-guided technologies for target identification and deconvolution |
| Q30388048 | Improved knockdown from artificial microRNAs in an enhanced miR-155 backbone: a designer's guide to potent multi-target RNAi |
| Q36100793 | In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus |
| Q34160642 | In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation |
| Q36736715 | In vivo RNAi screens: concepts and applications |
| Q35750036 | In vivo delivery of cytoplasmic RNA virus-derived miRNAs |
| Q35576955 | Inducible and reversible lentiviral and Recombination Mediated Cassette Exchange (RMCE) systems for controlling gene expression |
| Q36135110 | Life in the fast lane: mammalian disease models in the genomics era. |
| Q89477862 | Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription |
| Q33814282 | Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer. |
| Q37550614 | Loss-of-function genetic tools for animal models: cross-species and cross-platform differences |
| Q62746316 | MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival |
| Q34366539 | MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma |
| Q35685245 | MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. |
| Q34417700 | Mini-clusters with mean probabilities for identifying effective siRNAs. |
| Q28677450 | Molecular characteristics and efficacy of 16D10 siRNAs in inhibiting root-knot nematode infection in transgenic grape hairy roots |
| Q37353061 | Mouse model of intrahepatic cholangiocarcinoma validates FIG-ROS as a potent fusion oncogene and therapeutic target |
| Q34293007 | Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma |
| Q35455068 | MysiRNA-designer: a workflow for efficient siRNA design |
| Q35665146 | Next-generation libraries for robust RNA interference-based genome-wide screens. |
| Q60623955 | Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import |
| Q35731554 | Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim. |
| Q36195793 | Optimized models for design of efficient miR30-based shRNAs |
| Q30410731 | Organic small hairpin RNAs (OshR): a do-it-yourself platform for transgene-based gene silencing. |
| Q92040783 | PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism |
| Q42760471 | PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras |
| Q34196262 | PTEN action in leukaemia dictated by the tissue microenvironment |
| Q40996455 | Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc |
| Q36298062 | Prediction of potent shRNAs with a sequential classification algorithm |
| Q38918720 | Quantitative evaluation of first, second, and third generation hairpin systems reveals the limit of mammalian vector-based RNAi. |
| Q38081701 | RNA viruses and the host microRNA machinery |
| Q42201291 | RNAi in Xenopus: look before you leap |
| Q28654521 | RNAi screening comes of age: improved techniques and complementary approaches |
| Q34033373 | RNAi screening: new approaches, understandings, and organisms |
| Q34436638 | Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation. |
| Q36255190 | Recombinase-based conditional and reversible gene regulation via XTR alleles |
| Q96952210 | Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe |
| Q47572675 | Refined sgRNA efficacy prediction improves large- and small-scale CRISPR-Cas9 applications |
| Q28512942 | Reversible suppression of an essential gene in adult mice using transgenic RNA interference |
| Q33838294 | Reversible suppression of cyclooxygenase 2 (COX-2) expression in vivo by inducible RNA interference |
| Q36249769 | Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effects |
| Q35876214 | SHAPE-directed discovery of potent shRNA inhibitors of HIV-1. |
| Q33885667 | Sensor and sensitivity: a screen for elite shRNAs |
| Q37541395 | Sequence-specific inhibition of microRNA via CRISPR/CRISPRi system. |
| Q37713621 | Simultaneous gene editing by injection of mRNAs encoding transcription activator-like effector nucleases into mouse zygotes |
| Q46090732 | Small RNA biology: from fundamental studies to applications |
| Q38173633 | Stable RNA interference rules for silencing |
| Q38709651 | Synthetic lethality and cancer. |
| Q33635602 | Systematic design and functional analysis of artificial microRNAs. |
| Q47248814 | The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 mediates its association with KRAB-associated protein 1 (KAP1) and KAP1 target genes |
| Q36236290 | The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain |
| Q49243720 | The IAP family member BRUCE regulates autophagosome-lysosome fusion |
| Q36432986 | The microcosmos of cancer |
| Q41331438 | The non-coding RNA landscape of human hematopoiesis and leukemia. |
| Q35734891 | Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy |
| Q37890867 | Towards systematic functional characterization of cancer genomes |
| Q37038076 | Transcriptional plasticity promotes primary and acquired resistance to BET inhibition |
| Q35855833 | Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle |
| Q42251066 | Versatile and enhanced tumour modelling in mice via somatic cell transduction |
| Q37086614 | Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation. |
| Q34510032 | Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs |
| Q89766075 | let-7-Complex MicroRNAs Regulate Broad-Z3, Which Together with Chinmo Maintains Adult Lineage Neurons in an Immature State |
| Q36757075 | miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction |