HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers

scientific article

HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1046882709
P356DOI10.1186/S13058-015-0658-0
P932PMC publication ID4672555
P698PubMed publication ID26643555
P5875ResearchGate publication ID286402613

P50authorAndrea CalifanoQ29053203
David Llobet-NavasQ55729270
Wendy A WoodwardQ61037731
Daniel BirnbaumQ64516222
P2093author name stringJose Silva
Mary L Alpaugh
Min Yang
François Bertucci
Pascal Finetti
Jiyang Yu
Steven N Quayle
Preeti Putcha
Ruth Rodriguez-Barrueco
Veronica Castro
Patricia Villagrasa
Laura Saucedo-Cuevas
Eva Murga-Penas
P2860cites workARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular ContextQ21284234
HDAC6 is a microtubule-associated deacetylaseQ24298013
Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperoneQ24300246
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stressQ24301895
Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemiaQ24310753
Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagyQ24311582
A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centersQ24318306
HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signalingQ24319032
Endoplasmic reticulum stress: cell life and death decisions.Q24536108
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
Comprehensive molecular characterization of human colon and rectal cancerQ24630415
Comprehensive molecular portraits of human breast tumoursQ24630844
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypesQ24647928
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
Molecular portraits of human breast tumoursQ28032461
HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregatesQ28114913
Proliferation, cell cycle and apoptosis in cancerQ28189476
Cell death: critical control pointsQ28240722
Comprehensive molecular profiling of lung adenocarcinomaQ28244995
Second-generation shRNA libraries covering the mouse and human genomesQ28275183
Principles of cancer therapy: oncogene and non-oncogene addictionQ29616779
Genetic screens in human cells using the CRISPR-Cas9 systemQ29617411
Inflammatory breast cancer: an overviewQ38280412
Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancyQ38995507
Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cellsQ39843809
Profiling essential genes in human mammary cells by multiplex RNAi screeningQ40018285
Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alphaQ40236336
A novel human xenograft model of inflammatory breast cancer.Q41698493
Gene expression profiling identifies molecular subtypes of inflammatory breast cancerQ42475875
Molecular determinants of the inflammatory breast cancer phenotypeQ46131097
Potent and selective HDAC6 inhibitory activity of N-(4-hydroxycarbamoylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorenes as novel sulfur analogues of Tubastatin A.Q49131145
Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.Q52564601
A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivityQ63383824
A Bayesian framework for the analysis of microarray expression data: regularized t -test and statistical inferences of gene changesQ29618085
Reverse engineering of regulatory networks in human B cellsQ30004211
Cyfip1 is a putative invasion suppressor in epithelial cancersQ30490635
A resource for large-scale RNA-interference-based screens in mammals.Q33200135
Cancer proliferation gene discovery through functional genomics.Q33317743
The transcriptional network for mesenchymal transformation of brain tumours.Q33572162
Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cellsQ33680909
Trends in inflammatory breast carcinoma incidence and survival: the surveillance, epidemiology, and end results program at the National Cancer InstituteQ33751139
High-resolution comparative genomic hybridization of inflammatory breast cancer and identification of candidate genesQ33826097
Identification of human housekeeping genes and tissue-selective genes by microarray meta-analysisQ33983496
Reverse-engineering human regulatory networksQ34026195
High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencingQ34054107
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.Q34268870
Treating breast cancer in the 21st century: emerging biological therapiesQ34326536
A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosisQ34398390
Pooled shRNA screenings: experimental approachQ34566186
Pooled shRNA screenings: computational analysis.Q34566191
Inflammatory breast cancer (IBC): clues for targeted therapiesQ34754098
Functional identification of optimized RNAi triggers using a massively parallel sensor assayQ35088838
Functional viability profiles of breast cancerQ35281860
Inflammatory breast cancer management in the national comprehensive cancer network: the disease, recurrence pattern, and outcomeQ35576639
The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylaseQ35774565
Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myelomaQ35915726
Inhibition of the autocrine IL-6-JAK2-STAT3-calprotectin axis as targeted therapy for HR-/HER2+ breast cancersQ35952745
Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapyQ36559283
The lymphovascular embolus of inflammatory breast cancer expresses a stem cell-like phenotypeQ36778291
HDAC6 a new cellular stress surveillance factor.Q37057578
Highly parallel identification of essential genes in cancer cellsQ37068513
The medical treatment of inflammatory breast cancerQ37097315
Oxidative stress induces degradation of mitochondrial DNAQ37181498
Rapid creation and quantitative monitoring of high coverage shRNA librariesQ37440284
Mitochondrial stress: a bridge between mitochondrial dysfunction and metabolic diseases?Q37880356
Mechanism of action of proteasome inhibitors and deacetylase inhibitors and the biological basis of synergy in multiple myelomaQ37954600
Interplay between HDAC6 and its interacting partners: essential roles in the aggresome-autophagy pathway and neurodegenerative diseasesQ38220520
Genomic profiling of inflammatory breast cancer: a review.Q38226700
P2507corrigendum / erratumErratum to: HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers.Q42361021
P433issue1
P304page(s)149
P577publication date2015-12-08
P1433published inBreast Cancer ResearchQ2208481
P1476titleHDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers
P478volume17

Reverse relations

cites work (P2860)
Q48358070ARID1A-mutated ovarian cancers depend on HDAC6 activity
Q60920019Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis
Q42361021Erratum to: HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers.
Q59066462Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells
Q58768571Histone deacetylase 6 in cancer
Q89450261Histone deacetylase 6 regulates the immunosuppressive properties of cancer-associated fibroblasts in breast cancer through the STAT3-COX2-dependent pathway
Q63366138Inflammatory breast cancer biology: the tumour microenvironment is key
Q39153404Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex
Q90068431Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials
Q90526354Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways
Q89995921Selective Inhibition of Histone Deacetylases 1/2/6 in Combination with Gemcitabine: A Promising Combination for Pancreatic Cancer Therapy
Q92704418Targeting Non-Oncogene Addiction: Focus on Thyroid Cancer

Q42361021Erratum to: HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers.main subjectP921

Search more.