Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.

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Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1003926
P932PMC publication ID3916413
P698PubMed publication ID24516390
P5875ResearchGate publication ID260154925

P50authorGabriel NúñezQ63409996
P2093author name stringYuan He
Luigi Franchi
Shiho Suzuki
Toshihiko Suzuki
Chihiro Sasakawa
Hitomi Mimuro
Raul Muñoz-Planillo
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Assembly, purification, and assay of the activity of the ASC pyroptosomeQ39956628
Contact of Shigella with host cells triggers release of Ipa invasins and is an essential function of invasivenessQ40806867
MxiK and MxiN interact with the Spa47 ATPase and are required for transit of the needle components MxiH and MxiI, but not of Ipa proteins, through the type III secretion apparatus of Shigella flexneriQ41466218
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A novel assay system implicates PtdIns(3,4)P(2), PtdIns(3)P, and PKC delta in intracellular production of reactive oxygen species by the NADPH oxidaseQ44283104
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophagesQ21131607
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The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activationQ24628062
Molecular mechanisms of inflammasome activation during microbial infectionsQ26866436
Regulation of inflammasome signalingQ26996605
Regulation of cell apoptosis by protein kinase c deltaQ28201453
Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA libraryQ28254886
Structural organization of the needle complex of the type III secretion apparatus of Shigella flexneriQ28258916
The versatility of Shigella effectorsQ28259971
Differential activation of the inflammasome by caspase-1 adaptors ASC and IpafQ28266417
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNAQ28504793
NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defenseQ28507530
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificityQ28508255
Phosphorylation of NLRC4 is critical for inflammasome activationQ28586109
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophagesQ28594887
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesisQ29617049
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasomeQ33733606
Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasomeQ33744674
Contribution of Salmonella typhimurium type III secretion components to needle complex formationQ33917651
Spa32 regulates a switch in substrate specificity of the type III secreton of Shigella flexneri from needle components to Ipa proteinsQ34314419
Involvement of protein kinase C-delta in DNA damage-induced apoptosis.Q35644623
Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.Q36154204
Sensing and reacting to microbes through the inflammasomesQ36253171
Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.Q36385761
Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion.Q36422508
Molecular alteration of the 140-megadalton plasmid associated with loss of virulence and Congo red binding activity in Shigella flexneriQ37056357
Salmonella flagellin is not a dominant protective antigen in oral immunization with attenuated live vaccine strainsQ37116553
Shigella deploy multiple countermeasures against host innate immune responses.Q37799075
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue2
P921main subjectinflammasome complexQ412405
P304page(s)e1003926
P577publication date2014-02-06
P1433published inPLOS PathogensQ283209
P1476titleShigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.
P478volume10

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