Role of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages

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Role of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID313187
P698PubMed publication ID2492973

P2093author name stringB Y Rubin
H W Murray
C D Rothermel
D Wellner
A M Granger
M J Oca
A Szuro-Sudol
D M Libby
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Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophanQ36254619
Failure to trigger the oxidative metabolic burst by normal macrophages: possible mechanism for survival of intracellular pathogensQ36343315
Role for endogenous and acquired peroxidase in the toxoplasmacidal activity of murine and human mononuclear phagocytesQ36983087
Killing of intracellular Leishmania donovani by lymphokine-stimulated human mononuclear phagocytes. Evidence that interferon-gamma is the activating lymphokineQ36992102
Gamma-interferon-induced inhibition of the growth of Rickettsia prowazekii in fibroblasts cannot be explained by the degradation of tryptophan or other amino acidsQ37010640
Induction of tryptophan catabolism is the mechanism for gamma-interferon-mediated inhibition of intracellular Chlamydia psittaci replication in T24 cellsQ37026650
Oxygen-independent inhibition of intracellular Chlamydia psittaci growth by human monocytes and interferon-gamma-activated macrophagesQ37902808
The anti-chlamydial and anti-proliferative activities of recombinant murine interferon-gamma are not dependent on tryptophan concentrations.Q37903686
Activation of tissue macrophages from AIDS patients: in vitro response of AIDS alveolar macrophages to lymphokines and interferon-gammaQ37903928
Gamma-interferon is the factor in lymphokine that activates human macrophages to inhibit intracellular Chlamydia psittaci replication.Q37906618
Lymphokine enhances oxygen-independent activity against intracellular pathogensQ37906871
Indoleamine 2,3-dioxygenase. Purification and some propertiesQ39196665
Interferon-gamma, the activated macrophage, and host defense against microbial challengeQ39601454
Oxygen Metabolism and the Toxic Properties of PhagocytesQ40122453
Mechanisms of macrophage antimicrobial activityQ40167273
Activation of human macrophages. Comparison of other cytokines with interferon-gammaQ42232581
Killing of intracellular Leishmania donovani by human mononuclear phagocytes. Evidence for oxygen-dependent and -independent leishmanicidal activityQ42789825
Interferon-gamma suppresses the growth of Toxoplasma gondii in human fibroblasts through starvation for tryptophanQ45350192
Mechanism of interferon-gamma action. Characterization of indoleamine 2,3-dioxygenase in cultured human cells induced by interferon-gamma and evaluation of the enzyme-mediated tryptophan degradation in its anticellular activity.Q50897682
Characterization of an indoleamine 2,3-dioxygenase induced by gamma-interferon in cultured human fibroblastsQ68971567
Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell culturesQ69005518
Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gammaQ69937763
Human mononuclear phagocyte antiprotozoal mechanisms: oxygen-dependent vs oxygen-independent activity against intracellular Toxoplasma gondiiQ70078033
The actions of interferon and antiinflammatory agents of induction of indoleamine 2,3-dioxygenase in human peripheral blood monocytesQ70339987
The anticellular and protein-inducing activities of human gamma interferon preparations are mediated by the interferonQ70425115
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
P304page(s)845-849
P577publication date1989-03-01
P1433published inInfection and ImmunityQ6029193
P1476titleRole of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages
P478volume57

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