Muscle-derived interleukin-6: lipolytic, anti-inflammatory and immune regulatory effects

scientific article

Muscle-derived interleukin-6: lipolytic, anti-inflammatory and immune regulatory effects is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S00424-002-0981-Z
P698PubMed publication ID12690457

P50authorBente Klarlund PedersenQ12303219
Mark A FebbraioQ98196847
Pernille KellerQ114341859
Natalie J HiscockQ114388010
Gerrit van HallQ42260000
Christian P. FischerQ44013919
Peter PlomgaardQ54574972
Adam SteensbergQ56477409
Charlotte KellerQ56487448
P2860cites workNovel path to activation of vascular smooth muscle cells: up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptorQ22010614
Xanthine oxidase in human skeletal muscle following eccentric exercise: a role in inflammationQ24530189
Exercise-induced increase in serum interleukin-6 in humans is related to muscle damageQ24530194
Pro- and anti-inflammatory cytokine balance in strenuous exercise in humansQ24651495
A trauma-like elevation of plasma cytokines in humans in response to treadmill runningQ24653794
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin ResistanceQ28131660
Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-ATQ28139459
Transcription factors of the NFAT family: regulation and functionQ28237645
Inositol trisphosphate and calcium signallingQ28262867
Muscle-derived interleukin-6: possible biological effectsQ28361640
Carbohydrate ingestion attenuates the increase in plasma interleukin-6, but not skeletal muscle interleukin-6 mRNA, during exercise in humansQ28366249
Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-alphaQ73190307
Circulating cytokines and hormones with immunosuppressive but neutrophil-priming potentials rise after endurance exercise in humansQ73421984
Carbohydrate affects natural killer cell redistribution but not activity after runningQ73823236
Effects of mode and carbohydrate on the granulocyte and monocyte response to intensive, prolonged exerciseQ74357568
Effects of training on exercise-induced muscle damage and interleukin 6 productionQ74452578
Influence of mode and carbohydrate on the cytokine response to heavy exertionQ74552004
The cytokine response to strenuous exerciseQ77634722
Insulin-Stimulated Muscle Glucose Clearance in Patients With NIDDM: Effects of One-Legged Physical TrainingQ72015336
Role of epinephrine in TNF and IL-6 production from isolated perfused rat liverQ72199225
Endocrinologic and metabolic effects of interleukin-6 in humansQ72268044
Induction of plasma interleukin-6 by circulating adrenaline in the ratQ72440145
Constitutive and cytokine-induced production of interleukin-6 by human myoblastsQ72630529
Role of corticosterone in TNF and IL-6 production in isolated perfused rat liverQ72655604
Exercise elevates plasma levels but not gene expression of IL-1beta, IL-6, and TNF-alpha in blood mononuclear cellsQ73010306
Some aspects of the acute phase response after a marathon race, and the effects of glutamine supplementationQ73010518
Effect of prolonged, submaximal exercise and carbohydrate ingestion on monocyte intracellular cytokine production in humansQ73145027
A phase I clinical trial of recombinant human tumor necrosis factorQ33448324
Mechanisms of TNF-alpha-induced insulin resistanceQ33631090
Leukemia inhibitory factor, Interleukin 6, and other cytokines using the GP130 transducing receptor: roles in inflammation and injuryQ33643942
The role of TNF alpha in adipocyte metabolism.Q33650737
The role of TNFalpha and TNF receptors in obesity and insulin resistanceQ33680471
Tumor necrosis factor-alpha-induced insulin resistance in adipocytesQ33827934
Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?Q33829116
Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men.Q33898507
Exercise and the immune system: regulation, integration, and adaptationQ33909390
Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss.Q33918774
Physical activity and plasma interleukin-6 in humans--effect of intensity of exercise.Q33934108
Remodeling muscles with calcineurinQ33936668
Special feature for the Olympics: effects of exercise on the immune system: modification of immune responses to exercise by carbohydrate, glutamine and anti-oxidant supplementsQ34069920
Muscle-derived interleukin-6: mechanisms for activation and possible biological rolesQ34146938
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alphaQ34190131
Anti-gamma interferon and anti-interleukin-6 antibodies affect staphylococcal enterotoxin B-induced weight loss, hypoglycemia, and cytokine release in D-galactosamine-sensitized and unsensitized mice.Q35397408
Tumor necrosis factor and the acute metabolic response to tissue injury in manQ35591593
T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6.Q36363056
Tumor necrosis factor. Characterization at the molecular, cellular and in vivo levelQ36404676
The expression of TNF alpha by human muscle. Relationship to insulin resistanceQ37352139
Interferons and tumor necrosis factors have similar catabolic effects on 3T3 L1 cellsQ37406101
Induction of interleukin 6 (IL-6) by hypoxia in vascular cells. Central role of the binding site for nuclear factor-IL-6.Q38295384
The leucocytosis of exercise. A review and modelQ39565657
Calcium signaling in neurons: molecular mechanisms and cellular consequencesQ40506441
The cytokine response to strenuous exerciseQ40608390
Recombinant Human Tumor Necrosis Factor Administered as a 24-Hour Intravenous Infusion. A Phase I and Pharmacologic StudyQ40783265
Tumor necrosis factor and endotoxin induce similar metabolic responses in human beingsQ40784780
Clinical pharmacology of recombinant human tumor necrosis factor in patients with advanced cancerQ40791581
Interleukin-6 in biology and medicineQ40850225
TNF-alpha impairs insulin signaling and insulin stimulation of glucose uptake in C2C12 muscle cellsQ40954084
Effect of tumor necrosis factor-alpha on insulin action in cultured rat skeletal muscle cellsQ41196884
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM.Q41275648
Immune response to heavy exertionQ41458102
Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoidQ41722978
Effect of proinflammatory interleukins on jejunal nutrient transportQ42259565
Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetesQ42493190
Effects of tumor necrosis factor-alpha on insulin action in cultured human muscle cellsQ42503776
Interleukin-6 enhances glucose transport in 3T3-L1 adipocytesQ42518230
Circulating monocytes are not the source of elevations in plasma IL-6 and TNF-alpha levels after prolonged running.Q43540328
Lack of IL-6 production during exercise in patients with mitochondrial myopathyQ43631136
Intracellular monocyte and serum cytokine expression is modulated by exhausting exercise and cold exposureQ43638756
Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretionQ43668496
Plasma interleukin-6 during strenuous exercise: role of epinephrineQ43705424
Strenuous exercise decreases the percentage of type 1 T cells in the circulationQ43745455
Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content.Q43785444
Interleukin-6-deficient mice develop mature-onset obesityQ43851625
Cytokine response to eccentric exercise in young and elderly humansQ44021432
Neutralization of tumor necrosis factor reverses age-induced impairment of insulin responsiveness in skeletal muscle of Sprague-Dawley ratsQ44081485
The effect of graded exercise on IL-6 release and glucose uptake in human skeletal muscleQ44267771
Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6.Q44424615
Cytokines and chemokines are both expressed by human myoblasts: possible relevance for the immune pathogenesis of muscle inflammationQ45870452
A variety of cytokines and immunologically relevant surface molecules are expressed by normal human skeletal muscle cells under proinflammatory stimuliQ45889170
Effects of tumor necrosis factor-alpha on glucose metabolism in cultured human muscle cells from nondiabetic and type 2 diabetic subjectsQ46248752
Interleukin-6 stimulates hepatic triglyceride secretion in ratsQ46353326
Carbohydrate and the cytokine response to 2.5 h of runningQ46402044
Relationship between serum tumor necrosis factor-alpha and insulin resistance in obese men with Type 2 diabetes mellitus.Q51549607
Serum levels of tumor necrosis factor-alpha are increased in obese patients with noninsulin-dependent diabetes mellitus.Q54144879
Effect of training on the dose-response relationship for insulin action in men.Q54360914
Bicycle exercise enhances plasma IL-6 but does not change IL-1 alpha, IL-1 beta, IL-6, or TNF-alpha pre-mRNA in BMNCQ57609663
Prolonged submaximal eccentric exercise is associated with increased levels of plasma IL-6Q58172368
[Fatty tissue and insulin resistance: resistin and adiponectin]Q58448663
Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen contentQ58818196
Exercise induces hepatosplanchnic release of heat shock protein 72 in humansQ59326285
Chemokines are elevated in plasma after strenuous exercise in humansQ59326322
N-3 polyunsaturated fatty acids do not affect cytokine response to strenuous exerciseQ59326331
Muscle contractions induce interleukin-6 mRNA production in rat skeletal musclesQ59326338
A High Plasma Concentration of TNF- Is Associated With Dementia in CentenariansQ59326375
Evidence that interleukin-6 is produced in human skeletal muscle during prolonged runningQ59326390
Lymphocytes and NK cell activity during repeated bouts of maximal exerciseQ59326423
Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF-alpha and IL-1 beta productionQ70984018
Effects of tumour necrosis factor alpha (TNF alpha) on glucose transport and lipid metabolism of newly-differentiated human fat cells in cell cultureQ71736954
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)9-16
P577publication date2003-02-18
P1433published inPfluegers ArchivQ1091689
P1476titleMuscle-derived interleukin-6: lipolytic, anti-inflammatory and immune regulatory effects
P478volume446

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