Functional synthetic Antennapedia genes and the dual roles of YPWM motif and linker size in transcriptional activation and repression

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Functional synthetic Antennapedia genes and the dual roles of YPWM motif and linker size in transcriptional activation and repression is …
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scholarly articleQ13442814

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P819ADS bibcode2011PNAS..10811959P
P356DOI10.1073/PNAS.1108686108
P932PMC publication ID3141989
P698PubMed publication ID21712439
P5875ResearchGate publication ID51451335

P50authorDiana L Cárdenas-ChávezQ56721747
Diana Resendez-PerezQ56893469
Dimitrios K PapadopoulosQ84077879
P2093author name stringRicardo Canales-del-Castillo
Daniel A Felix
Walter J Gehring
Karina Villanueva-Segura
Raphael Fünfschilling
P2860cites workStructure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formationQ22008845
The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD fingerQ24291405
Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of DrosophilaQ24595240
The Hexapeptide and Linker Regions of the AbdA Hox Protein Regulate Its Activating and Repressive FunctionsQ47925666
Homeotic response elements are tightly linked to tissue-specific elements in a transcriptional enhancer of the teashirt gene.Q52206448
Identification of target genes of the homeotic gene Antennapedia by enhancer detection.Q52235028
In vivo analysis of the helix-turn-helix motif of the fushi tarazu homeo domain of Drosophila melanogaster.Q52441650
The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain.Q52447848
The YPWM motif links Antennapedia to the basal transcriptional machinery.Q52689753
A homoeotic mutation transforming leg to antenna in DrosophilaQ59071155
Setting limits on homeotic gene function: restraint of Sex combs reduced activity by teashirt and other homeotic genesQ24596294
Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complexQ27617465
The des(1-6)antennapedia homeodomain: comparison of the NMR solution structure and the DNA-binding affinity with the intact Antennapedia homeodomainQ27730565
Targeted gene expression as a means of altering cell fates and generating dominant phenotypesQ27861039
Homeobox genes and axial patterningQ28181571
Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteinsQ28243184
Functional dissection of the mouse Hox-a5 geneQ28585623
Modulating Hox gene functions during animal body patterningQ29012458
A gene complex controlling segmentation in DrosophilaQ29547506
Reprogramming control of an allosteric signaling switch through modular recombinationQ31002823
Homeobox genes in the ribbonworm Lineus sanguineus: evolutionary implicationsQ32097182
Hox specificity unique roles for cofactors and collaboratorsQ33607453
Quantitative study of synthetic Hox transcription factor-DNA interactions in live cellsQ33732788
Function and specificity of synthetic Hox transcription factors in vivo.Q33732917
Two distinct types of repression domain in engrailed: one interacts with the groucho corepressor and is preferentially active on integrated target genesQ33786539
Transposition of cloned P elements into Drosophila germ line chromosomes.Q34253758
A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexesQ34255549
Molecular basis for the inhibition of Drosophila eye development by Antennapedia.Q34582563
The control of trunk Hox specificity and activity by ExtradenticleQ35200880
Alternative RNA products from the Ultrabithorax domain of the bithorax complex.Q35977218
Opinion: antibody-based therapies for malariaQ36302325
Functional specificity of the Antennapedia homeodomainQ36408422
Alternative RNA splicing that is spatially regulated: generation of transcripts from the Antennapedia gene of Drosophila melanogaster with different protein-coding regionsQ36846552
Shaping segments: Hox gene function in the genomic age.Q37271912
Internal regulatory interactions determine DNA binding specificity by a Hox transcription factor.Q37337672
Non-homeodomain regions of Hox proteins mediate activation versus repression of Six2 via a single enhancer site in vivoQ37468603
Evolution of the Hox gene complex from an evolutionary ground stateQ37570811
Homeo boxes in the study of developmentQ39462903
Alternative splicing modulates Ubx protein function in Drosophila melanogasterQ39792261
Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factorsQ40130015
Homeodomain-DNA recognitionQ40680227
Two distinct domains of Bicoid mediate its transcriptional downregulation by the Torso pathway.Q40787669
Dissecting the functional specificities of two Hox proteinsQ42174676
Spatial and temporal targeting of gene expression in Drosophila by means of a tetracycline-dependent transactivator system.Q44166531
Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity.Q44717180
Evolutionarily conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax.Q45930457
Cofactor-interaction motifs and the cooption of a homeotic Hox protein into the segmentation pathway of Drosophila melanogasterQ46961533
Spalt major controls the development of the notum and of wing hinge primordia of the Drosophila melanogaster wing imaginal disc.Q47070482
Distal antenna and distal antenna related encode nuclear proteins containing pipsqueak motifs involved in antenna development in DrosophilaQ47071434
P433issue29
P407language of work or nameEnglishQ1860
P304page(s)11959-11964
P577publication date2011-06-28
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleFunctional synthetic Antennapedia genes and the dual roles of YPWM motif and linker size in transcriptional activation and repression
P478volume108

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cites work (P2860)
Q35126388A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity
Q50715931Developmental competence and the induction of ectopic proboscises in Drosophila melanogaster.
Q26824950Differential pleiotropy and HOX functional organization
Q47072425Dimer formation via the homeodomain is required for function and specificity of Sex combs reduced in Drosophila.
Q26865492Disentangling the many layers of eukaryotic transcriptional regulation
Q27316136Drosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19
Q37213980Mechanisms of Specificity for Hox Factor Activity.
Q37420939Radiation-sensitising effects of antennapedia proteins (ANTP)-SmacN7 on tumour cells
Q54966054Regulation of Silk Genes by Hox and Homeodomain Proteins in the Terminal Differentiated Silk Gland of the Silkworm Bombyx mori.
Q57465564Transcription factor TFIIEβ interacts with two exposed positions in helix 2 of the Antennapedia homeodomain to control homeotic function in Drosophila
Q38820846Transcriptional regulators form diverse groups with context-dependent regulatory functions
Q46985143We also CanFly! The 2nd MexFly drosophila research conference

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