Diurnal patterns of soluble amyloid precursor protein metabolites in the human central nervous system

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Diurnal patterns of soluble amyloid precursor protein metabolites in the human central nervous system is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...989998D
P356DOI10.1371/JOURNAL.PONE.0089998
P932PMC publication ID3960093
P698PubMed publication ID24646516
P5875ResearchGate publication ID260949433

P50authorVitaliy OvodQ59943870
Justyna A Dobrowolska ZakariaQ60376755
Tom P KastenQ114573545
Wendy C. SigurdsonQ114573558
Yafei HuangQ114573573
Tammie L. BenzingerQ56154010
John C. MorrisQ56839763
Randall J. BatemanQ39888114
P2860cites work[11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer diseaseQ60451990
Soluble amyloid precursor protein α and β in CSF in Alzheimer's diseaseQ48103753
Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester.Q48519738
Circadian characteristics of sleep propensity function in healthy elderly: a comparison with young adultsQ48733289
Clinical and neurobiological correlates of soluble amyloid precursor proteins in the cerebrospinal fluid.Q51392734
Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study.Q51872146
Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease.Q51983988
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.Q51986028
Fluctuations of CSF amyloid-beta levels: implications for a diagnostic and therapeutic biomarker.Q53285087
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACEQ22010705
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activityQ22010912
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor proteinQ22251280
Global prevalence of dementia: a Delphi consensus studyQ24603249
Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycleQ24644961
Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor proteinQ24650599
Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitorQ27675616
Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi networkQ28143129
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor proteinQ28260479
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-BQ29012704
Sleep drives metabolite clearance from the adult brainQ29620065
Effects of age and amyloid deposition on Aβ dynamics in the human central nervous systemQ34215733
The nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer beta/A4-amyloid precursor protein: some technical notesQ35582069
Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older womenQ35630404
Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptideQ36578141
Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older womenQ36694340
Disruption of the sleep-wake cycle and diurnal fluctuation of β-amyloid in mice with Alzheimer's disease pathologyQ36845156
β-amyloid dynamics in human plasmaQ37254727
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activityQ37357625
Alzheimer's disease: the challenge of the second centuryQ37862502
Biology and pathophysiology of the amyloid precursor proteinQ37869935
Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adultsQ40253365
Measurement of alpha- and beta-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patientsQ44574707
High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype.Q45192211
In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.Q46835118
Correlations between soluble α/β forms of amyloid precursor protein and Aβ38, 40, and 42 in human cerebrospinal fluidQ48088716
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)e89998
P577publication date2014-03-19
P1433published inPLOS OneQ564954
P1476titleDiurnal patterns of soluble amyloid precursor protein metabolites in the human central nervous system
P478volume9

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