Targeted expression of a dominant-negative EGF-R in the kidney reduces tubulo-interstitial lesions after renal injury

scientific article published in July 2000

Targeted expression of a dominant-negative EGF-R in the kidney reduces tubulo-interstitial lesions after renal injury is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI8315
P932PMC publication ID314303
P698PubMed publication ID10903338
P5875ResearchGate publication ID12416667

P50authorGérard FriedlanderQ39659602
P2093author name stringF Terzi
P Briand
P Federici
G Grimber
M Burtin
M Hekmati
P2860cites workTargeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotypeQ28509173
Epidermal growth factor receptor expression is abnormal in murine polycystic kidneyQ28510252
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Epidermal growth factor or transforming growth factor alpha is required for kidney tubulogenesis in matrigel cultures in serum-free mediumQ33597644
Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic miceQ34140717
Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice.Q34341740
Early role of Fsp1 in epithelial-mesenchymal transformationQ34445512
Epidermal growth factor enhances renal tubule cell regeneration and repair and accelerates the recovery of renal function in postischemic acute renal failureQ34580512
Nature and severity of the glomerular response to nephron reduction is strain-dependent in miceQ35786298
Effects of epidermal growth factor on collagen synthesis by an epithelioid cell line derived from normal rat kidneyQ35811714
Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneysQ35832710
An activated allele of the c-erbB-2 oncogene impairs kidney and lung function and causes early death of transgenic miceQ36232599
Identification and characterization of a fibroblast marker: FSP1Q36382596
Molecular mechanisms of tubulointerstitial hypertrophy and hyperplasiaQ36397797
HMG-CoA reductase inhibitors induce apoptosis in mouse proximal tubular cells in primary cultureQ36885797
Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney diseaseQ37378446
Potential physiologic roles for epidermal growth factor in the kidneyQ37738853
Reduction of renal mass is lethal in mice lacking vimentin. Role of endothelin-nitric oxide imbalanceQ39790972
A progressive glomerulosclerosis occurring in partial five-sixths nephrectomized ratsQ39926230
Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutantsQ40653709
A dominant negative mutation suppresses the function of normal epidermal growth factor receptors by heterodimerizationQ40677644
Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structureQ40789769
Epidermal growth factor and the kidneyQ40876362
Osteopontin regulation in cultured rat renal epithelial cellsQ41107943
Mechanisms of recovery from mechanical injury of renal tubular epithelial cellsQ41449763
Progression of renal damage in human glomerulonephritides: is there sleight of hand in winning the game?Q41667549
Early molecular mechanisms in the progression of renal failure: role of growth factors and protooncogenesQ41743379
Increased distal nephron EGF content and altered distribution of peptide in compensatory renal hypertrophyQ41919771
Normal tubular regeneration and differentiation of the post-ischemic kidney in mice lacking vimentin.Q42059569
EGF-induced mitogenesis in proximal tubular cells: potentiation by angiotensin II.Q42510124
Renal tubular cells are potential targets for epidermal growth factorQ43585904
Expression of epidermal growth factor in the rat kidney. An immunocytochemical and in situ hybridization study.Q43744071
Transient increase in renal epidermal growth factor content after unilateral nephrectomy in the mouseQ46177717
Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptorQ46766121
The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinaseQ48084939
Pattern of expression of gamma-glutamyl transpeptidase in rat liver and kidney during development: study by immunochemistry and in situ hybridization.Q53506982
Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats.Q54471089
Strain-dependent epithelial defects in mice lacking the EGF receptorQ58326927
Renal effect of anti-hypertensive drugs depends on sodium diet in the excision remnant kidney modelQ67560073
Segmental distribution of epidermal growth factor binding sites in rabbit nephronQ68573417
Epidermal growth factor is expressed by cells in the distal tubules during postnephrectomy renal growthQ68820010
Epidermal growth factor accelerates renal repair in mercuric chloride nephrotoxicityQ68911965
Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cellsQ70146276
Subtotal but not unilateral nephrectomy induces hyperplasia and protooncogene expressionQ71695873
Reversal of lung lesions in transgenic transforming growth factor alpha mice by expression of mutant epidermal growth factor receptorQ71701920
Renal cysts in transgenic mice expressing transforming growth factor-alphaQ72182430
Subtotal nephrectomy: a mosaic of growth factorsQ72337333
Autocrine, endocrine and paracrine regulation of growth abnormalities in autosomal dominant polycystic kidney diseaseQ72564205
Met -/- kidneys express epithelial cells that chemotax and form tubules in response to EGF receptor ligandsQ73281511
Hypoxia stimulates proximal tubular cell matrix production via a TGF-beta1-independent mechanismQ73683729
Subtotal nephrectomy alters tubular function: effect of phosphorus restrictionQ73961032
Epidermal growth factor receptor and transforming growth factor alpha expression in papillary and nonpapillary renal cell carcinoma: correlation with metastatic behavior and prognosisQ77556038
Mouse-human chimeric anti-epidermal growth factor receptor antibody C225 inhibits the growth of human renal cell carcinoma xenografts in nude miceQ77726919
The course of the remnant kidney model in miceQ78016673
Experimentally induced chronic renal insufficiency in the ratQ79026802
Sodium restriction decreases AP-1 activation after nephron reduction in the rat: role in the progression of renal lesionsQ95820930
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)225-234
P577publication date2000-07-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleTargeted expression of a dominant-negative EGF-R in the kidney reduces tubulo-interstitial lesions after renal injury
P478volume106

Reverse relations

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