scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1046808338 |
P356 | DOI | 10.1038/NM.3313 |
P698 | PubMed publication ID | 24056770 |
P50 | author | Andrea Onetti Muda | Q56428257 |
Frank Bienaimé | Q56959308 | ||
Gérard Friedlander | Q39659602 | ||
P2093 | author name string | Tobias B Huber | |
Mario Pende | |||
Andrea Onetti Muda | |||
Fabiola Terzi | |||
Marco Pontoglio | |||
Christophe Legendre | |||
Konstantinos Giannakakis | |||
Guillaume Canaud | |||
Amandine Viau | |||
Stefan Zschiedrich | |||
Clément Nguyen | |||
Caroline Treins | |||
Sophie Berissi | |||
Martine Burtin | |||
William Baron | |||
P2860 | cites work | Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton | Q24299873 |
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity | Q24598427 | ||
AKT/PKB signaling: navigating downstream | Q24657857 | ||
Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta | Q24669877 | ||
Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice | Q43726502 | ||
Sirolimus interacts with pathways essential for podocyte integrity | Q45151652 | ||
Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy. | Q46510650 | ||
Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis | Q46522437 | ||
Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach | Q46616535 | ||
The Notch pathway in podocytes plays a role in the development of glomerular disease | Q46725170 | ||
Proteinuria following a switch from calcineurin inhibitors to sirolimus | Q46825307 | ||
Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes. | Q46886156 | ||
The PI3K/Akt/mTOR pathway is activated in murine lupus nephritis and downregulated by rapamycin. | Q51547435 | ||
Modification of kidney barrier function by the urokinase receptor. | Q53510545 | ||
mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome. | Q54351691 | ||
Signaling in regulation of podocyte phenotypes. | Q54774137 | ||
Podocyte-specific expression of cre recombinase in transgenic mice | Q57740867 | ||
Mammalian Target of Rapamycin Inhibition Halts the Progression of Proteinuria in a Rat Model of Reduced Renal Mass | Q59531350 | ||
Opposing Roles for Akt1 and Akt2 in Rac/Pak Signaling and Cell Migration | Q60155829 | ||
Age-associated changes in renal glomeruli of mice | Q69627600 | ||
Renoprotective effects of sirolimus in non-immune initiated focal segmental glomerulosclerosis | Q80433109 | ||
Effects of rapamycin on active Heymann nephritis | Q80482229 | ||
Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death | Q81007653 | ||
Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without hypertension: a meta-analysis | Q26995926 | ||
Podocin inactivation in mature kidneys causes focal segmental glomerulosclerosis and nephrotic syndrome | Q28256662 | ||
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB | Q28306356 | ||
Proliferation and remodeling of the peritubular microcirculation after nephron reduction: association with the progression of renal lesions | Q28345280 | ||
Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis | Q28504659 | ||
Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling | Q28611533 | ||
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta) | Q29615537 | ||
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice | Q30500731 | ||
Long-term benefits with sirolimus-based therapy after early cyclosporine withdrawal | Q33359653 | ||
Induction of B7-1 in podocytes is associated with nephrotic syndrome | Q33785088 | ||
The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. | Q33943247 | ||
Proteinuria: an enzymatic disease of the podocyte? | Q33943310 | ||
Lipocalin 2 is essential for chronic kidney disease progression in mice and humans | Q34245315 | ||
TGF-alpha mediates genetic susceptibility to chronic kidney disease. | Q34534909 | ||
Hyperfiltration and glomerulosclerosis | Q35110865 | ||
Targeted expression of a dominant-negative EGF-R in the kidney reduces tubulo-interstitial lesions after renal injury | Q35126310 | ||
Inhibition of podocyte FAK protects against proteinuria and foot process effacement. | Q35153198 | ||
Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes | Q35916016 | ||
Molecular determinants of the physiological adaptation to stress in the cardiomyocyte: a focus on AKT. | Q35937270 | ||
Pathways to nephron loss starting from glomerular diseases-insights from animal models | Q36021181 | ||
Podocyte-specific loss of Cdc42 leads to congenital nephropathy | Q36050935 | ||
The podocyte's response to injury: role in proteinuria and glomerulosclerosis | Q36474870 | ||
Podocytes in culture: past, present, and future | Q36801026 | ||
Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton | Q36931220 | ||
The PI3K/Akt pathway: recent progress in the development of ATP-competitive and allosteric Akt kinase inhibitors | Q37089913 | ||
Intracellular signaling by Akt: bound to be specific | Q37193392 | ||
Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria | Q37330532 | ||
Mechanical stretch and prostaglandin E2 modulate critical signaling pathways in mouse podocytes. | Q39719517 | ||
Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease | Q39912709 | ||
mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes | Q39914641 | ||
Banff 07 classification of renal allograft pathology: updates and future directions | Q40121163 | ||
Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase | Q40533718 | ||
Progression of renal disease and renal hypertrophy | Q40543219 | ||
Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin | Q40545315 | ||
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice | Q41912848 | ||
Insulin signaling to the glomerular podocyte is critical for normal kidney function | Q42110064 | ||
Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1 | Q42592859 | ||
P433 | issue | 10 | |
P921 | main subject | chronic renal insufficiency | Q736715 |
P304 | page(s) | 1288-1296 | |
P577 | publication date | 2013-09-22 | |
P1433 | published in | Nature Medicine | Q1633234 |
P1476 | title | AKT2 is essential to maintain podocyte viability and function during chronic kidney disease | |
P478 | volume | 19 |