β2-Glycoprotein I-specific T cells are associated with epitope spread to lupus-related autoantibodies

scientific article

β2-Glycoprotein I-specific T cells are associated with epitope spread to lupus-related autoantibodies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M114.619817
P932PMC publication ID4342469
P698PubMed publication ID25555913

P50authorYuka OkazakiQ62673249
P2093author name stringMasataka Kuwana
Jerrold S Levine
Joyce Rauch
Rebecca Subang
David Salem
Patrick Laplante
P2860cites workHLA class II alleles associations of anticardiolipin and anti-beta2GPI antibodies in a large series of European patients with systemic lupus erythematosusQ28138464
T cells that are autoreactive to beta2-glycoprotein I in patients with antiphospholipid syndrome and healthy individualsQ28143036
Analysis of T cell responses to the beta 2-glycoprotein I-derived peptide library in patients with anti-beta 2-glycoprotein I antibody-associated autoimmunityQ30846733
Cellular immunity to beta 2-glycoprotein-1 in patients with the antiphospholipid syndromeQ33329031
The prevalence, onset, and clinical significance of antiphospholipid antibodies prior to diagnosis of systemic lupus erythematosusQ33360375
Subclinical atherosclerosis in systemic lupus erythematosus and antiphospholipid syndrome: focus on β2GPI-specific T cell responseQ33412737
Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a beta 2-glycoprotein I-dependent mannerQ33496605
Oral tolerance to low dose beta 2-glycoprotein I: immunomodulation of experimental antiphospholipid syndromeQ33504372
Identification of a region of beta 2-glycoprotein I critical for lipid binding and anti-cardiolipin antibody cofactor activityQ36157442
T cells demonstrate a Th1-biased response to native beta2-glycoprotein I in a murine model of anti-phospholipid antibody inductionQ36194551
Immunization with an apoptotic cell-binding protein recapitulates the nephritis and sequential autoantibody emergence of systemic lupus erythematosusQ36227184
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytesQ36363024
Ro 60 functions as a receptor for beta(2)-glycoprotein I on apoptotic cells.Q39879086
Diverse TCRs recognize murine CD1.Q40981487
Phospholipid-binding proteins differ in their capacity to induce autoantibodies and murine systemic lupus erythematosusQ46586191
Impaired clearance of apoptotic cells induces the activation of autoreactive anti-Sm marginal zone and B-1 B cellsQ47305440
Systemic lupus erythematosus.Q53202066
Advanced glycation end products of human β₂ glycoprotein I modulate the maturation and function of DCs.Q54596172
Induction of active and adoptive relapsing experimental autoimmune encephalomyelitis (EAE) using an encephalitogenic epitope of proteolipid proteinQ67537170
Phospholipid-dependent anti-beta 2-glycoprotein I (beta 2-GPI) antibodies and antiphospholipid syndromeQ71187590
Adoptive transfer of beta(2)-glycoprotein I-reactive lymphocytes enhances early atherosclerosis in LDL receptor-deficient miceQ73054106
Immune clearance of phosphatidylserine-expressing cells by phagocytes. The role of beta2-glycoprotein I in macrophage recognitionQ73919900
Autoreactive CD4(+) T-cell clones to beta2-glycoprotein I in patients with antiphospholipid syndrome: preferential recognition of the major phospholipid-binding siteQ74459320
Development of Autoantibodies before the Clinical Onset of Systemic Lupus ErythematosusQ79171865
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectautoantibodyQ785022
P304page(s)5543-5555
P577publication date2015-01-02
P1433published inJournal of Biological ChemistryQ867727
P1476titleβ2-Glycoprotein I-specific T cells are associated with epitope spread to lupus-related autoantibodies
P478volume290

Reverse relations

cites work (P2860)
Q54996884Cellular and Molecular Mechanisms of Anti-Phospholipid Syndrome.
Q89158649Different domains of β2-glycoprotein I play a role in autoimmune pathogenesis
Q52724555T cells from induced and spontaneous models of SLE recognize a common T cell epitope on β2-glycoprotein I.
Q93020058The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS
Q60961044β2-Glycoprotein I-Reactive T Cells in Autoimmune Disease

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