Differentially expressed miRNAs in Ewing sarcoma compared to mesenchymal stem cells: low miR-31 expression with effects on proliferation and invasion.

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Differentially expressed miRNAs in Ewing sarcoma compared to mesenchymal stem cells: low miR-31 expression with effects on proliferation and invasion. is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...993067K
P356DOI10.1371/JOURNAL.PONE.0093067
P8608Fatcat IDrelease_773ik5dxmzhx7byx3q3xclfa5e
P932PMC publication ID3965523
P698PubMed publication ID24667836
P5875ResearchGate publication ID261103348

P50authorAndreas RanftQ59841400
P2093author name stringElizabeth R Lawlor
Uta Dirksen
Andreas Bräuninger
Stefan Gattenlöhner
Tilmann Spieker
Heribert Jürgens
Nicolas Dedy
Bianca Karnuth
P2860cites workAn integrated analysis of miRNA and gene copy numbers in xenografts of Ewing's sarcomaQ21198840
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Pro-tumorigenic effects of miR-31 loss in mesotheliomaQ24607181
Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancersQ24634248
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasisQ24649156
Most mammalian mRNAs are conserved targets of microRNAsQ24655061
Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcomaQ28239992
A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERGQ28252253
Causes and consequences of microRNA dysregulation in cancerQ28258994
MiRNA expression in urothelial carcinomas: important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31Q28305980
Changes in incidence and survival of Ewing sarcoma patients over the past 3 decades: Surveillance Epidemiology and End Results data.Q31157886
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Modeling initiation of Ewing sarcoma in human neural crest cellsQ33894979
Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trialQ50784397
The predictive potential of molecular detection in the nonmetastatic Ewing family of tumorsQ51019815
EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells.Q53487773
EWS-FLI1 and EWS-ERG gene fusions are associated with similar clinical phenotypes in Ewing's sarcoma.Q54158232
Increased risk of systemic relapses associated with bone marrow micrometastasis and circulating tumor cells in localized ewing tumor.Q54797647
Polycomb-mediated loss of miR-31 activates NIK-dependent NF-κB pathway in adult T cell leukemia and other cancers.Q55239231
Risk of recurrence and survival after relapse in patients with Ewing sarcomaQ83731173
Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cellsQ33992270
Safety assessment of intensive induction with vincristine, ifosfamide, doxorubicin, and etoposide (VIDE) in the treatment of Ewing tumors in the EURO-E.W.I.N.G. 99 clinical trialQ33994512
Let-7a is a direct EWS-FLI-1 target implicated in Ewing's sarcoma developmentQ33997274
Mesenchymal stem cell features of Ewing tumorsQ34003979
EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance.Q34283431
Antagonism pattern detection between microRNA and target expression in Ewing's sarcomaQ34358973
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiationQ34963463
MetastamiRs: non-coding MicroRNAs driving cancer invasion and metastasisQ35795725
Locked nucleic acid: high-affinity targeting of complementary RNA for RNomics.Q36440340
Recent advances in the molecular pathogenesis of Ewing's sarcomaQ36562720
EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.Q36701142
Concomitant suppression of three target genes can explain the impact of a microRNA on metastasisQ37426806
Metastamirs: a stepping stone towards improved cancer managementQ37806613
A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAsQ38334606
Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcomaQ38338166
Tumor suppressive microRNAs (miR-222 and miR-31) regulate molecular pathways based on microRNA expression signature in prostate cancer.Q39304020
A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcomaQ39331421
miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancyQ39465507
EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cellsQ39716224
Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cellsQ39757723
Autocrine- and paracrine-activated receptor tyrosine kinases in classic Hodgkin lymphomaQ45242163
Results of the EICESS-92 Study: two randomized trials of Ewing's sarcoma treatment--cyclophosphamide compared with ifosfamide in standard-risk patients and assessment of benefit of etoposide added to standard treatment in high-risk patientsQ46359097
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmesenchymal stem cellQ1922379
P304page(s)e93067
P577publication date2014-03-25
P1433published inPLOS OneQ564954
P1476titleDifferentially expressed miRNAs in Ewing sarcoma compared to mesenchymal stem cells: low miR-31 expression with effects on proliferation and invasion
P478volume9

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cites work (P2860)
Q35652286A trans-ethnic genome-wide association study identifies gender-specific loci influencing pediatric aBMD and BMC at the distal radius.
Q55663842Deep RNA sequencing reveals the dynamic regulation of miRNA, lncRNAs, and mRNAs in osteosarcoma tumorigenesis and pulmonary metastasis.
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Q38296481MicroRNA expression and its clinical implications in Ewing's sarcoma
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Q38667026microRNA and Bone Cancer

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