Systems pharmacology dissection of the anti-inflammatory mechanism for the medicinal herb Folium eriobotryae

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Systems pharmacology dissection of the anti-inflammatory mechanism for the medicinal herb Folium eriobotryae is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS16022913
P932PMC publication ID4346873
P698PubMed publication ID25636035
P5875ResearchGate publication ID273954305

P2093author name stringLing Yang
Yan Li
Yonghua Wang
Lilei Zhang
Jinghui Wang
Shuwei Zhang
Yanqiu Pan
Yinfeng Yang
Jingxiao Zhang
Su-Shing Chen
P2860cites workUse of NSAIDs in treating patients with arthritisQ21195252
Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathwayQ83878859
Anti-inflammatory effect of triterpenoic Acids of Eriobotrya japonica (Thunb.) Lindl. Leaf on rat model of chronic bronchitisQ84025582
Anti-metastatic properties of the leaves of Eriobotrya japonicaQ84050778
Anti-inflammatory effects of flavonoids [etc.]Q21342966
Cytoscape: a software environment for integrated models of biomolecular interaction networksQ24515682
DrugBank 3.0: a comprehensive resource for 'omics' research on drugsQ24612505
Pharmacogenomics knowledge for personalized medicineQ24623166
Inflammation and cancerQ24649640
SWISS-MODEL: An automated protein homology-modeling serverQ24672647
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studiesQ27650733
A cross-cultural study: anti-inflammatory activity of Australian and Chinese plantsQ28194898
Chlorogenic acid bioavailability largely depends on its metabolism by the gut microflora in ratsQ28207260
Cardiovascular hazard and non-steroidal anti-inflammatory drugsQ28210980
The cytotoxic activity of ursolic acid derivativesQ28253461
Pharmacology of oleanolic acid and ursolic acidQ28292594
A system-level investigation into the mechanisms of Chinese Traditional Medicine: Compound Danshen Formula for cardiovascular disease treatmentQ28483412
Prediction of drug-target interactions and drug repositioning via network-based inferenceQ28483634
A systematic prediction of multiple drug-target interactions from chemical, genomic, and pharmacological dataQ28484011
Evidence for antiradical and antioxidant properties of four biologically active N,N-Diethylaminoethyl ethers of flavaone oximes: A comparison with natural polyphenolic flavonoid rutin actionQ29302214
Error and attack tolerance of complex networksQ29547268
Drug-target networkQ29614447
NF-kappaB: a key role in inflammatory diseasesQ29617726
Anti-Proliferative Activities and Apoptosis Induction by Triterpenes Derived from Eriobotrya japonica in Human Leukemia Cell LinesQ30394095
Polyphenols from Eriobotrya japonica and their cytotoxicity against human oral tumor cell linesQ30596594
Prediction of 'drug-likeness'.Q30829130
Selection criteria for drug-like compoundsQ30901599
Rapid and simple method for screening of natural antioxidants from Chinese herb Flos Lonicerae Japonicae by DPPH-HPLC-DAD-TOF/MS.Q33373389
Loquat (Eriobotrya japonica) extracts suppress the adhesion, migration and invasion of human breast cancer cell lineQ33601971
Cancer inflammation and regulatory T cellsQ33796582
Network target for screening synergistic drug combinations with application to traditional Chinese medicineQ33937467
Dietary intake and bioavailability of polyphenolsQ33985768
Lonicera japonica Thunb.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine.Q34001980
TNF-alpha as a therapeutic target in inflammatory diseases, ischemia-reperfusion injury and traumaQ34018999
Neuroprotective effects of Eriobotrya japonica against β-amyloid-induced oxidative stress and memory impairment.Q34025039
The inflammatory reflexQ34165907
Harmless herbs? A review of the recent literatureQ34462670
Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cellsQ34532617
Mechanisms underlying the cardiovascular effects of COX-inhibition: benefits and risksQ34661938
Systems pharmacology in drug discovery and therapeutic insight for herbal medicinesQ48465967
Protective changes of inflammation-related gene expression by the leaves of Eriobotrya japonica in the LPS-stimulated human gingival fibroblast: microarray analysis.Q51549709
Physicochemical properties and oral bioavailability of ursolic acid nanoparticles using supercritical anti-solvent (SAS) process.Q51564505
Terpenoid Constituents ofAbies chensiensiswith Potential Anti-inflammatory ActivityQ58339070
Hypoglycemic Effects of Sesquiterpene Glycosides and Polyhydroxylated Triterpenoids ofEriobotrya japonicaQ60695460
Anti-inflammatory activity of oleanolic acid in rats and miceQ67523188
Effect of Eriobotrya japonica on blood glucose levels of normal and alloxan-diabetic rabbitsQ67940896
Anti-inflammatory constituents of topically applied crude drugs. I. Constituents and anti-inflammatory effect of Eriobotrya japonica LINDLQ69638289
The relationship between infection and inflammation in the early stages of lung disease from cystic fibrosisQ70921818
Relationships between structure and high-throughput screening permeability of peptide derivatives and related compounds with artificial membranes: application to prediction of Caco-2 cell permeabilityQ75211567
Hypoglycemic effects of a sesquiterpene glycoside isolated from leaves of loquat (Eriobotrya japonica (Thunb.) Lindl.).Q79754787
The benefits of the multi-target approach in drug design and discoveryQ81306317
Anti-inflammatory and antinociceptive properties of the leaves of Eriobotrya japonicaQ83019037
Network analyses in systems pharmacologyQ34995155
Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti-inflammatory effectQ35044050
ADMET in silico modelling: towards prediction paradise?Q35075770
p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseasesQ35209995
Systems pharmacology dissection of multi-scale mechanisms of action for herbal medicines in stroke treatment and preventionQ35219375
Inhibition of signal transduction pathways involved in inflammationQ35569933
The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailabilityQ35620976
Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery.Q35631111
Inflammatory resolution: new opportunities for drug discoveryQ35770168
PPARs: therapeutic targets for metabolic diseaseQ36110177
Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic miceQ37331058
Metabolite profiling and characterization for medicinal herbal remediesQ37980233
A novel chemometric method for the prediction of human oral bioavailabilityQ38323150
Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugsQ39394038
The chemistry and biological significance of saponins in foods and feedingstuffsQ39669367
Luteolin isolated from the flowers of Lonicera japonica suppresses inflammatory mediator release by blocking NF-kappaB and MAPKs activation pathways in HMC-1 cellsQ39746551
Anti-inflammatory effect of leaves of Eriobotrya japonica correlating with attenuation of p38 MAPK, ERK, and NF-kappaB activation in mast cellsQ39814955
Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines.Q39836797
Eriobotrya japonica leaf and its triterpenes inhibited lipopolysaccharide-induced cytokines and inducible enzyme production via the nuclear factor-kappaB signaling pathway in lung epithelial cellsQ39909627
Evaluation of the anti-inflammatory, analgesic and antipyretic activities of the natural polyphenol chlorogenic acid.Q40465837
New insights into the mode of action of anti-inflammatory drugsQ40476391
Effect of olive oil minor components on oxidative stress and arachidonic acid mobilization and metabolism by macrophages RAW 264.7.Q40624187
Kaempferol and quercetin isolated from Euonymus alatus improve glucose uptake of 3T3-L1 cells without adipogenesis activityQ42817087
Eriobotryae folium extract suppresses LPS-induced iNOS and COX-2 expression by inhibition of NF-kappaB and MAPK activation in murine macrophagesQ42915311
Anti-inflammatory and immunomodulating properties of a sterol fraction from Sideritis foetens Clem.Q43622244
Megastigmane glycosides and an acylated triterpenoid from Eriobotrya japonica.Q43650131
Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cellsQ43829644
Constituents of Eriobotrya japonica. A Study of Their Antiviral PropertiesQ43847068
Antitumor activity of compounds isolated from leaves of Eriobotrya japonicaQ43944705
Transepithelial transport of chlorogenic acid, caffeic acid, and their colonic metabolites in intestinal caco-2 cell monolayersQ44868116
Protective effects of luteolin-7-glucoside against liver injury caused by carbon tetrachloride in rats.Q44882364
Effect of leaves of Eriobotrya japonica on anaphylactic allergic reaction and production of tumor necrosis factor-alpha.Q45974652
Hypoglycemic and hypolipidemic effects of the total triterpene acid fraction from Folium Eriobotryae.Q46017878
Hypoglycemic effect of the total flavonoid fraction from folium Eriobotryae.Q46019115
Cinchonain Ib isolated from Eriobotrya japonica induces insulin secretion in vitro and in vivo.Q46034819
Chlorogenic acid inhibits lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 cells through suppressing NF-kappaB and JNK/AP-1 activation.Q46037249
Euscaphic acid, a new hypoglycemic natural product from Folium Eriobotryae.Q46274140
Hypoglycemic activity of Eriobotrya japonica seeds in type 2 diabetic rats and miceQ46716070
Anti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of Eriobotrya japonicaQ46736034
Anti-inflammatory and apoptotic activities of pomolic acid isolated from Cecropia pachystachya.Q46764689
Antioxidant activity of caffeic acid (3,4-dihydroxycinnamic acid).Q46769117
Anti-oxidative effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf in chronic bronchitis ratsQ46849550
Pharmacological studies on anti-hyperglycemic effect of folium eriobotryaeQ47760859
Systems approaches and polypharmacology for drug discovery from herbal medicines: an example using licoriceQ47784795
Bridging the traditional Chinese medicine pattern classification and biomedical disease diagnosis with systems biologyQ47804351
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesCytoscapeQ3699942
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmedicinal plantQ188840
P304page(s)2913-2941
P577publication date2015-01-28
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleSystems pharmacology dissection of the anti-inflammatory mechanism for the medicinal herb Folium eriobotryae
P478volume16

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cites work (P2860)
Q33685427A New Strategy for Deleting Animal drugs from Traditional Chinese Medicines based on Modified Yimusake Formula.
Q52744118A comprehensive review of recent studies on pharmacokinetics of traditional Chinese medicines (2014-2017) and perspectives.
Q37612650Elucidation of the Anti-Inflammatory Mechanisms of Bupleuri and Scutellariae Radix Using System Pharmacological Analyses
Q54941668Exploring the Pharmacological Mechanism of Danzhi Xiaoyao Powder on ER-Positive Breast Cancer by a Network Pharmacology Approach.
Q60938890Identification of Pharmacokinetic Markers for Guanxin Danshen Drop Pills in Rats by Combination of Pharmacokinetics, Systems Pharmacology, and Pharmacodynamic Assays
Q28601167Investigation of the Anti-Inflammatory and Analgesic Activities of Ethanol Extract of Stem Bark of Sonapatha Oroxylum indicum In Vivo
Q64116804Medicinal Herbs Effective Against Atherosclerosis: Classification According to Mechanism of Action
Q26782866Systems Biology - A Pivotal Research Methodology for Understanding the Mechanisms of Traditional Medicine
Q33809040Systems Pharmacological Approach of Pulsatillae Radix on Treating Crohn's Disease
Q90536722Systems Pharmacological Approach to Investigate the Mechanism of Acori Tatarinowii Rhizoma for Alzheimer's Disease
Q47145365Systems Pharmacological Approach to the Effect of Bulsu-san Promoting Parturition.
Q61449212Systems Pharmacology Dissection of Multi-Scale Mechanisms of Action of Formula for the Treatment of Gastrointestinal Diseases
Q37710808Systems Pharmacology-based strategy to screen new adjuvant for hepatitis B vaccine from Traditional Chinese Medicine Ophiocordyceps sinensis
Q47141505Uncovering the Pharmacological Mechanism of Astragalus Salvia Compound on Pregnancy-Induced Hypertension Syndrome by a Network Pharmacology Approach

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