Uncovering the Pharmacological Mechanism of Astragalus Salvia Compound on Pregnancy-Induced Hypertension Syndrome by a Network Pharmacology Approach

scientific article published on 4 December 2017

Uncovering the Pharmacological Mechanism of Astragalus Salvia Compound on Pregnancy-Induced Hypertension Syndrome by a Network Pharmacology Approach is …
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scholarly articleQ13442814

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P356DOI10.1038/S41598-017-17139-X
P932PMC publication ID5715142
P698PubMed publication ID29203792

P2093author name stringKailin Yang
Liuting Zeng
Jinwen Ge
P2860cites workAn automated method for finding molecular complexes in large protein interaction networksQ21284295
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disordersQ24558589
TCMSP: a database of systems pharmacology for drug discovery from herbal medicinesQ27703005
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
Network pharmacology: the next paradigm in drug discoveryQ28297997
Information flow analysis of interactome networksQ28475566
The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databasesQ28660703
Network medicine: a network-based approach to human diseaseQ29547462
STRING v10: protein-protein interaction networks, integrated over the tree of lifeQ29615545
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-YinQ30393827
A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use.Q30433214
A network pharmacology approach to evaluating the efficacy of chinese medicine using genome-wide transcriptional expression dataQ30640970
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of interleukin 6.Q51139503
Exploring the pharmacological mechanism of Yanghe Decoction on HER2-positive breast cancer by a network pharmacology approach.Q51165443
Increased oxidative stress from early pregnancy in women who develop preeclampsia.Q53196491
Calcium supplementation during pregnancy: a systematic review of randomised controlled trialsQ57281576
Prevention of preeclampsia with low-dose aspirin in healthy, nulliparous pregnant women. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine UnitsQ61845775
The role of the spiral arteries in the pathogenesis of preeclampsiaQ69446253
Tumor necrosis factor-alpha is elevated in plasma and amniotic fluid of patients with severe preeclampsiaQ72516832
Relationships between structure and high-throughput screening permeability of peptide derivatives and related compounds with artificial membranes: application to prediction of Caco-2 cell permeabilityQ75211567
Is oxidative stress the link in the two-stage model of pre-eclampsia?Q78258200
Association of maternal KIR and fetal HLA-C genes with the risk of preeclampsia in the Chinese Han population, Long et alQ85533189
Pathogenesis of preeclampsia: Implications of apoptotic markers and oxidative stressQ86441103
Traditional Chinese medicine network pharmacology: theory, methodology and applicationQ86982948
Plasma nitric oxide, endothelin-1, arginase and superoxide dismutase in the plasma and placentae from preeclamptic patientsQ87345859
Prediction of 'drug-likeness'.Q30829130
Recombinant vascular endothelial growth factor 121 infusion lowers blood pressure and improves renal function in rats with placentalischemia-induced hypertensionQ33666742
Antiartherosclerotic effects of plant flavonoidsQ33757899
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approachQ33957682
Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in PregnancyQ34379583
Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusionQ34655444
Plasma IL-17, IL-35, interferon-γ, SOCS3 and TGF-β levels in pregnant women with preeclampsia, and their relation with severity of diseaseQ34657074
Recent Insights into the pathogenesis of pre-eclampsiaQ34682287
Pharmacological management of hypertension in pregnancyQ34746979
Chinese herbal prescriptions for osteoarthritis in Taiwan: analysis of National Health Insurance datasetQ35114033
Systems pharmacology dissection of the anti-inflammatory mechanism for the medicinal herb Folium eriobotryaeQ35138964
Th1/Th2 balance in preeclampsiaQ35190885
Decidual natural killer cell receptor expression is altered in pregnancies with impaired vascular remodeling and a higher risk of pre-eclampsiaQ35227748
Preeclampsia: recent insightsQ36288757
Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: systematic review and meta-analysisQ36721468
Hypertension in response to chronic reductions in uterine perfusion in pregnant rats: effect of tumor necrosis factor-alpha blockadeQ37459545
Deep placentationQ37826560
Kaempferol, a potential cytostatic and cure for inflammatory disordersQ38242153
A novel chemometric method for the prediction of human oral bioavailabilityQ38323150
Kaempferol and inflammation: From chemistry to medicineQ38486477
SMFM Statement: benefit of antihypertensive therapy for mild-to-moderate chronic hypertension during pregnancy remains uncertainQ38500416
Cytotrophoblasts up-regulate soluble fms-like tyrosine kinase-1 expression under reduced oxygen: an implication for the placental vascular development and the pathophysiology of preeclampsiaQ40530224
Nitric oxide and pregnancyQ41449537
Nitric oxide and shockQ41481595
The herbal medicines Saireito and Boiogito improve the hypertension of pre-eclamptic rats induced by Nomega-Nitro-L-arginine methyl esterQ42165037
The herbal medicine Toki-shakuyaku-san improves the hypertension and intrauterine growth retardation in preeclampsia rats induced by Nomega-nitro-L-arginine methyl esterQ44769238
Risk factors for pre-eclampsia in an Asian populationQ45013645
Effect of quercetine and glutathione on the level of superoxide dismutase, catalase, malonyldialdehyde, blood pressure and neonatal outcome in a rat model of pre-eclampsia induced by NG-nitro-L-arginine-methyl esterQ45226263
Tanshinone II-A: new perspectives for old remediesQ45746307
[Treatment of albuminuria in gestational hypertension puerpera in the severe preeclampeia stage by TCM therapy for stasis-removing and diuresis].Q45957329
Effect of ingredients of Astragalus-Salvia compound on vascular endothelial cell in placenta and vascular endothelial growth factor mRNA expression in trophocyte in pregnant rats with inhibited nitric oxide synthesisQ46605642
Oxidative stress and changes in antioxidative defense system in erythrocytes of preeclampsia in womenQ46811002
A network pharmacology approach to determine active ingredients and rationality of herb combinations of Modified-Simiaowan for treatment of goutQ47425656
A clinical study on TCM differentiation of symptoms and signs in pregnancy hypertension syndrome.Q47813214
The herbal medicine Tokishakuyakusan increases fetal blood glucose concentrations and growth hormone levels and improves intrauterine growth retardation induced by N(omega)-nitro-L-arginine methyl esterQ48089045
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesCytoscapeQ3699942
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
P304page(s)16849
P577publication date2017-12-04
P1433published inScientific ReportsQ2261792
P1476titleUncovering the Pharmacological Mechanism of Astragalus Salvia Compound on Pregnancy-Induced Hypertension Syndrome by a Network Pharmacology Approach
P478volume7

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cites work (P2860)
Q90148460Applications of Network Pharmacology in Traditional Chinese Medicine Research
Q92638755Combining an in silico approach with an animal experiment to investigate the protective effect of troxerutin for treating acute lung injury
Q64072211Computational prediction and in vitro validation of VEGFR1 as a novel protein target for 2,3,7,8-tetrachlorodibenzo-p-dioxin
Q61450535Correlation of gestational hypertension with abnormal lipid metabolism, insulin resistance and D-dimer and their clinical significance
Q64097708Effect of the drug combination of magnesium sulfate and phentolamine on homocysteine and C-reactive protein in the serum of patients with pregnancy-induced hypertension syndrome
Q60915315Exploring the Mechanism of Danshen against Myelofibrosis by Network Pharmacology and Molecular Docking
Q91717812Exploring the Pharmacological Mechanism of Quercetin-Resveratrol Combination for Polycystic Ovary Syndrome: A Systematic Pharmacological Strategy-Based Research
Q55093753Reverse Screening Methods to Search for the Protein Targets of Chemopreventive Compounds.
Q92130485Study on the Material Basis of Houpo Wenzhong Decoction by HPLC Fingerprint, UHPLC-ESI-LTQ-Orbitrap-MS, and Network Pharmacology
Q52597677Uncovering the Mechanisms of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation by Focused Network Pharmacology Approach.
Q59811770Uncovering the mechanism of Maxing Ganshi Decoction on asthma from a systematic perspective: A network pharmacology study
Q89547353Use of a Systematic Pharmacological Methodology to Explore the Mechanism of Shengmai Powder in Treating Diabetic Cardiomyopathy

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