Exploring the Mechanism of Danshen against Myelofibrosis by Network Pharmacology and Molecular Docking

scientific article published on 05 December 2018

Exploring the Mechanism of Danshen against Myelofibrosis by Network Pharmacology and Molecular Docking is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1155/2018/8363295
P932PMC publication ID6304517
P698PubMed publication ID30622613

P50authorCun LiuQ57639366
Changgang SunQ90428176
Jie LiQ90951427
Xiaoran MaQ90951430
Huayao LiQ90951433
Jing ZhuangQ90951436
Chundi GaoQ90951439
Chao ZhouQ90951443
Lijuan LiuQ90951445
Kejia WangQ90951447
P2093author name stringJie Li
Chao Zhou
Kejia Wang
Lijuan Liu
Jing Zhuang
Cun Liu
Changgang Sun
Chundi Gao
Huayao Li
Xiaoran Ma
P2860cites workBone marrow fibrosis in primary myelofibrosis: pathogenic mechanisms and the role of TGF-βQ26745943
Network pharmacology: the next paradigm in drug discoveryQ28297997
Growth-inhibitory and apoptosis-inducing effects of tanshinones on hematological malignancy cells and their structure-activity relationshipQ34229249
New developments in the chemistry and biology of the bioactive constituents of TanshenQ34652663
Use of in-silico assays to characterize the ADMET profile and identify potential therapeutic targets of fusarochromanone, a novel anti-cancer agentQ35729725
The anti-inflammatory activities of ethanol extract from Dan-Lou prescription in vivo and in vitroQ35768547
Pathogenesis of myelofibrosis with myeloid metaplasiaQ36315447
A Network Pharmacology Approach to Explore the Pharmacological Mechanism of Xiaoyao Powder on Anovulatory InfertilityQ37547543
Ca(2+) Signalling in Endothelial Progenitor Cells: Friend or Foe?Q38561600
Oncogenic Drivers in Myeloproliferative Neoplasms: From JAK2 to Calreticulin MutationsQ38586919
Cryptotanshinone inhibits proliferation yet induces apoptosis by suppressing STAT3 signals in renal cell carcinomaQ38706677
Evaluation of the anti-inflammatory activities of tanshinones isolated from Salvia miltiorrhiza var. alba roots in THP-1 macrophagesQ38770994
Cryptotanshinone, a novel tumor angiogenesis inhibitor, destabilizes tumor necrosis factor-α mRNA via decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR.Q38840543
systemsDock: a web server for network pharmacology-based prediction and analysisQ40774775
Activating JAK2 mutants reveal cytokine receptor coupling differences that impact outcomes in myeloproliferative neoplasmQ41555800
Ligand and Structure-Based Approaches for the Identification of Peptide Deformylase Inhibitors as Antibacterial DrugsQ42397239
Cytotoxic Activities of Tanshinones Against Human Carcinoma Cell LinesQ46832937
Elevated TNF-alpha and LDH without parathormone disturbance is associated with diffuse osteolytic lesions in leukemic transformation of myelofibrosisQ46919254
Predicted molecular targets and pathways for germacrone, curdione, and furanodiene in the treatment of breast cancer using a bioinformatics approachQ47102370
Uncovering the Pharmacological Mechanism of Astragalus Salvia Compound on Pregnancy-Induced Hypertension Syndrome by a Network Pharmacology ApproachQ47141505
Danshen attenuates cartilage injuries in osteoarthritis in vivo and in vitro by activating JAK2/STAT3 and AKT pathwaysQ47576461
Prediction of anti-tumor chemical probes of a traditional Chinese medicine formula by HPLC fingerprinting combined with molecular dockingQ47628715
Trypsin inhibitor screening in traditional Chinese medicine by using an immobilized enzyme microreactor in capillary and molecular docking studyQ48314184
Preclinical rationale for TGF-β inhibition as a therapeutic target for the treatment of myelofibrosis.Q49196561
The 2016 WHO classification and diagnostic criteria for myeloproliferative neoplasms: document summary and in-depth discussionQ49633536
Antiproliferative activity and apoptosis induction by trijuganone C isolated from the root of Salvia miltiorrhiza Bunge (Danshen).Q49719650
New therapeutic strategies to treat human cancers expressing mutant p53 proteinsQ49962911
Myeloproliferative neoplasms: from origins to outcomes.Q49989025
Allogeneic stem-cell transplantation for myelofibrosis.Q50497802
Danshen attenuates osteoarthritis-related cartilage degeneration through inhibition of NF-κB signaling pathway in vivo and in vitro.Q50916624
Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial.Q51742255
Salvia miltiorrhizaBurge (Danshen): A golden herbal medicine in cardiovascular therapeutics.Q52561276
New Challenges in Targeting Signaling Pathways in Acute Lymphoblastic Leukemia by NGS Approaches: An Update.Q52593673
An Update on JAK Inhibitors.Q52626085
Cryptotanshinone sensitizes antitumor effect of paclitaxel on tongue squamous cell carcinoma growth by inhibiting the JAK/STAT3 signaling pathway.Q52753981
Novel Therapies for Myelofibrosis.Q52817185
Pharmacotherapy of Myelofibrosis.Q53119304
New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis.Q53683397
Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2-V617F mouse model of MPN.Q54296338
Cryptotanshinone inhibits IgE‑mediated degranulation through inhibition of spleen tyrosine kinase and tyrosine‑protein kinase phosphorylation in mast cells.Q54977741
Autocrine Tnf signaling favors malignant cells in myelofibrosis in a Tnfr2-dependent fashion.Q54979332
Recent advances in the diagnosis and management of primary myelofibrosis.Q54980872
Elevated expression of the EZH2 gene in CALR-mutated patients with primary myelofibrosis.Q54981942
A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer.Q54990524
Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancerQ57174076
VEGF expression correlates with microvessel density in Philadelphia chromosome-negative chronic myeloproliferative disordersQ79908847
Dysregulation of VEGF-induced proangiogenic Ca2+ oscillations in primary myelofibrosis-derived endothelial colony-forming cellsQ86367961
STAT3 and apoptosis challenges in cancerQ88758278
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesCytoscapeQ3699942
P407language of work or nameEnglishQ1860
P921main subjectmyelofibrosisQ1752571
pharmacologyQ128406
P304page(s)8363295
P577publication date2018-12-05
P1433published inEvidence-based Complementary and Alternative MedicineQ5418319
P1476titleExploring the Mechanism of Danshen against Myelofibrosis by Network Pharmacology and Molecular Docking
P478volume2018

Reverse relations

cites work (P2860)
Q92593539Based on network pharmacology to explore the molecular mechanisms of astragalus membranaceus for treating T2 diabetes mellitus
Q90705503Exploring Pharmacological Mechanisms of Xiang Ju Tablets in the Treatment of Allergic Rhinitis via a Network Pharmacology Approach
Q89558541Identifying Synergistic Mechanisms of Multiple Ingredients in Shuangbai Tablets against Proteinuria by Virtual Screening and a Network Pharmacology Approach
Q99557329Mechanisms of indigo naturalis on treating ulcerative colitis explored by GEO gene chips combined with network pharmacology and molecular docking
Q92997006Top-100 Most Cited Publications Concerning Network Pharmacology: A Bibliometric Analysis

Search more.