Hsc70 contributes to cancer cell survival by preventing Rab1A degradation under stress conditions

scientific article

Hsc70 contributes to cancer cell survival by preventing Rab1A degradation under stress conditions is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...996785T
P356DOI10.1371/JOURNAL.PONE.0096785
P932PMC publication ID4011886
P698PubMed publication ID24801886
P5875ResearchGate publication ID262110982

P50authorMasako TanakaQ82306912
Katsuyuki TakahashiQ84549017
Yasuyuki OhkawaQ39025369
P2093author name stringSoichi Sano
Katsuyuki Miura
Hideki Wanibuchi
Akihito Harada
Hiroshi Iwao
Masayuki Shiota
Yasukatsu Izumi
Mayuko Osada-Oka
Azusa Inagaki
Masayo Yamagata
Tokihito Yukimura
Saya Mun
P2860cites workThe Hallmarks of CancerQ221226
Autophagosome formation depends on the small GTPase Rab1 and functional ER exit sitesQ24320195
Chaperone-mediated autophagy: a unique way to enter the lysosome worldQ24628159
Hsp70 chaperones: cellular functions and molecular mechanismQ24644472
Exploiting tumour hypoxia in cancer treatmentQ28264146
Targeting heat shock proteins in cancerQ28298397
The Hsp70 and Hsp60 chaperone machinesQ29547601
How to interpret LC3 immunoblottingQ29614175
Principles of cancer therapy: oncogene and non-oncogene addictionQ29616779
Role of autophagy in cancerQ29620348
Puromycin-based vectors promote a ROS-dependent recruitment of PML to nuclear inclusions enriched with HSP70 and ProteasomesQ30862913
The small GTPase Ran: interpreting the signsQ30943625
Aberrant expression of RAB1A in human tongue cancer.Q33214689
Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cellsQ33326513
Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implicationsQ33899708
Cellular strategies for controlling protein aggregationQ34143451
Protein tyrosine phosphatase PTP20 induces actin cytoskeleton reorganization by dephosphorylating p190 RhoGAP in rat ovarian granulosa cells stimulated with follicle-stimulating hormoneQ34173472
Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle?Q34341935
Hsp70 architecture: the formation of novel polymeric structures of Hsp70.1 and Hsc70 after proteotoxic stress.Q34533688
Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathwaysQ35737974
HSP90 and HSP70 proteins are essential for stabilization and activation of WASF3 metastasis-promoting proteinQ35880133
Rab proteinsQ77135972
Generation of a rat monoclonal antibody specific for heat shock cognate protein 70Q82306919
Inhibition of autophagy and tumor growth in colon cancer by miR-502.Q36173829
Cotranslational response to proteotoxic stress by elongation pausing of ribosomesQ36604984
The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions.Q36838138
Inhibitors of the heat shock response: biology and pharmacologyQ36845355
The HSP70 family and cancerQ36895403
Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells.Q37033622
Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability.Q37084096
Direct and indirect association of the small GTPase ran with nuclear pore proteins and soluble transport factors: studies in Xenopus laevis egg extracts.Q37382182
Inhibition of HSP70: a challenging anti-cancer strategyQ38023055
Comprehensive review on the HSC70 functions, interactions with related molecules and involvement in clinical diseases and therapeutic potentialQ38041880
Microenvironment and tumor cell plasticity: an easy way out.Q38078708
Induction of apoptosis in murine neuroblastoma by systemic delivery of transferrin-shielded siRNA polyplexes for downregulation of Ran.Q38289174
Hsp70 inhibition induces myeloma cell death via the intracellular accumulation of immunoglobulin and the generation of proteotoxic stressQ39120344
A small molecule inhibitor of inducible heat shock protein 70.Q39789249
Overexpression of the heat-shock protein 70 is associated to imatinib resistance in chronic myeloid leukemiaQ40207892
Prevalidation of potential protein biomarkers in toxicology using iTRAQ reagent technologyQ40221975
Nuclear translocation of papillomavirus minor capsid protein L2 requires Hsc70.Q40556496
Aberrant expression of photoreceptor-specific calcium-binding protein (recoverin) in cancer cell lines.Q40887087
Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanismsQ41197754
Stress inhibits nucleocytoplasmic shuttling of heat shock protein hsc70.Q42814078
Mitochondrial Prohibitins and Septin 9 Are Implicated in the Onset of Rat HepatocarcinogenesisQ42863332
Heat shock cognate protein 70 is essential for Akt signaling in endothelial functionQ43216832
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)e96785
P577publication date2014-05-06
P1433published inPLOS OneQ564954
P1476titleHsc70 contributes to cancer cell survival by preventing Rab1A degradation under stress conditions
P478volume9

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cites work (P2860)
Q102210984Clinical value and potential association of Rab1A and FoxM1 aberrant expression in colorectal cancer
Q55493581Comprehensive transcriptomic analysis of heat shock proteins in the molecular subtypes of human breast cancer.
Q39329062Determining protein biomarkers for DLBCL using FFPE tissues from HIV negative and HIV positive patients.
Q47750277Endogenous epitope tagging of heat shock protein 70 isoform Hsc70 using CRISPR/Cas9.
Q35909654Experimental Adaptation of Rotaviruses to Tumor Cell Lines
Q90133961Expression analysis and implication of Rab1A in gastrointestinal relevant tumor
Q99579028Expression of Rab1A in bladder cancer and its clinical implications
Q38697766Heat shock protein 70 inhibitors suppress androgen receptor expression in LNCaP95 prostate cancer cells.
Q28554921Ophiobolin A Induces Autophagy and Activates the Mitochondrial Pathway of Apoptosis in Human Melanoma Cells
Q92088901Pooled analysis of prognostic value and clinical significance of Rab1A expression in human solid tumors
Q64089678Rab1A promotes proliferation and migration abilities via regulation of the HER2/AKT-independent mTOR/S6K1 pathway in colorectal cancer
Q93111322miR‑139‑3p suppresses the invasion and migration properties of breast cancer cells by targeting RAB1A

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