Hsp70 architecture: the formation of novel polymeric structures of Hsp70.1 and Hsc70 after proteotoxic stress.

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Hsp70 architecture: the formation of novel polymeric structures of Hsp70.1 and Hsc70 after proteotoxic stress. is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...752351S
P356DOI10.1371/JOURNAL.PONE.0052351
P932PMC publication ID3526589
P698PubMed publication ID23285004
P5875ResearchGate publication ID234043841

P50authorRobin L AndersonQ60683395
Rohan SteelQ80571605
Sarah EllisQ54107325
P2093author name stringRyan S Cross
P2860cites workConstitutive HSP70: oligomerization and its dependence on ATP bindingQ67578433
Analysis of protein binding to heat shock protein 70 in pancreatic islet cells exposed to elevated temperatures or interleukin 1 betaQ70146900
Cotranslocation and Colocalization of hsp40 (DnaJ) with hsp70 (DnaK) in Mammalian CellsQ71974320
Differential detergent fractionation of isolated hepatocytes: biochemical, immunochemical and two-dimensional gel electrophoresis characterization of cytoskeletal and noncytoskeletal compartmentsQ72048900
Polymerization of 70-kDa Heat Shock Protein by Yeast DnaJ in ATPQ72055097
Heat-induced alterations in the localization of HSP72 and HSP73 as measured by indirect immunohistochemistry and immunogold electron microscopyQ73462693
Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotoleranceQ73500626
Inhibition of Hsp70 ATPase activity and protein renaturation by a novel Hsp70-binding proteinQ22008496
hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondriaQ24306768
BAG-1 modulates the chaperone activity of Hsp70/Hsc70.Q24313113
Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70Q24338681
RNA granulesQ24683783
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Negative regulation of the Apaf-1 apoptosome by Hsp70Q28143100
Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formationQ28204279
Characterization of functional domains of the eukaryotic co-chaperone HipQ28581007
The Hsp70 and Hsp60 chaperone machinesQ29547601
Characteristics of a human cell line transformed by DNA from human adenovirus type 5Q29547863
The heat-shock responseQ29619473
Molecular chaperones and the cytoskeletonQ30427785
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosomeQ33912989
Dynamic changes in the localization of thermally unfolded nuclear proteins associated with chaperone-dependent protectionQ33946970
Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformationQ34425896
Sequential mechanism of solubilization and refolding of stable protein aggregates by a bichaperone networkQ34505864
Cell cycle-dependent association of HSP70 with specific cellular proteinsQ36220083
Interaction of hsp70 with unfolded proteins: effects of temperature and nucleotides on the kinetics of bindingQ37541312
Effects of expressing human Hsp70 and its deletion derivatives on heat killing and on RNA and protein synthesisQ38297273
Stress granulesQ39847472
Regulation of heat-induced apoptosis by Mcl-1 degradation and its inhibition by Hsp70.Q39894500
Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocationQ40371434
Hsp72 inhibits Fas-mediated apoptosis upstream of the mitochondria in type II cells.Q40474861
Heat shock protein 70 overexpression affects the response to ultraviolet light in murine fibroblasts. Evidence for increased cell viability and suppression of cytokine releaseQ41010028
Expression of a Drosophila heat shock protein in mammalian cells: transient association with nucleoli after heat shockQ41408932
Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicityQ41532748
Association of HSP72 with the nuclear (TX-100-insoluble) fraction upon heating tolerant and non-tolerant HeLa S3 cellsQ41580871
Characterization and dynamics of aggresome formation by a cytosolic GFP-chimeraQ42870983
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilizationQ42971215
Hsp72 inhibits apoptosis upstream of the mitochondria and not through interactions with Apaf-1.Q45061733
Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly.Q45950874
Heat shock protein 72 modulates pathways of stress-induced apoptosis.Q47921342
Hsp70 dynamics in vivo: effect of heat shock and protein aggregation.Q50792897
Hsc70/Hsp40 chaperone system mediates the Hsp90-dependent refolding of firefly luciferase.Q52575458
Interaction between hsp70 and hsp40, eukaryotic homologues of DnaK and DnaJ, in human cells expressing mutant-type p53.Q54618645
Uncoating ATPase is a member of the 70 kilodalton family of stress proteins.Q54781672
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)e52351
P577publication date2012-12-19
P1433published inPLOS OneQ564954
P1476titleHsp70 architecture: the formation of novel polymeric structures of Hsp70.1 and Hsc70 after proteotoxic stress
P478volume7

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cites work (P2860)
Q38754109Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death
Q35163915Hsc70 contributes to cancer cell survival by preventing Rab1A degradation under stress conditions

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