scholarly article | Q13442814 |
P2093 | author name string | D D Mosser | |
N Mohseni | |||
A M Livingstone | |||
A R Stankiewicz | |||
P2860 | cites work | MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain | Q22254196 |
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function | Q24293924 | ||
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak | Q24296478 | ||
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins | Q24302494 | ||
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis | Q24306444 | ||
Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1 | Q24308005 | ||
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members | Q24337108 | ||
The Bcl-2 apoptotic switch in cancer development and therapy | Q24620437 | ||
Structural insights into the degradation of Mcl-1 induced by BH3 domains | Q27644256 | ||
Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1 | Q28256819 | ||
BH3-ligand regulates access of MCL-1 to its E3 ligase | Q28276218 | ||
The chaperone function of hsp70 is required for protection against stress-induced apoptosis | Q28679271 | ||
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging | Q29614783 | ||
Apoptosis: controlled demolition at the cellular level | Q29620114 | ||
The multidomain proapoptotic molecules Bax and Bak are directly activated by heat | Q34212713 | ||
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells | Q34278532 | ||
Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons | Q34446404 | ||
Mcl-1. | Q35913618 | ||
Cooperation of molecular chaperones with the ubiquitin/proteasome system | Q35967558 | ||
Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa. | Q36117765 | ||
Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli | Q36246889 | ||
Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis | Q36364894 | ||
Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis | Q36571858 | ||
Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes | Q36799170 | ||
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? | Q37100016 | ||
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation | Q39895438 | ||
Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation. | Q39993903 | ||
A pivotal role for Mcl-1 in Bortezomib-induced apoptosis | Q40102590 | ||
Acute acidification or amiloride treatment suppresses the ability of Hsp70 to inhibit heat-induced apoptosis | Q40146133 | ||
Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation | Q40371434 | ||
MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol | Q40537978 | ||
Characterisation of Mcl-1 cleavage during apoptosis of haematopoietic cells | Q40555258 | ||
Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress | Q40704873 | ||
Induced thermotolerance to apoptosis in a human T lymphocyte cell line | Q41623364 | ||
Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells | Q43514949 | ||
Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events | Q44795441 | ||
Molecular chaperones and the stress of oncogenesis | Q47785215 | ||
Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells. | Q52546411 | ||
Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance | Q73500626 | ||
Functional linkage between NOXA and Bim in mitochondrial apoptotic events | Q79996271 | ||
Unraveling MCL-1 degradation | Q83368258 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | apoptotic process | Q14599311 |
P304 | page(s) | 638-647 | |
P577 | publication date | 2009-01-16 | |
P1433 | published in | Cell Death & Differentiation | Q2943974 |
P1476 | title | Regulation of heat-induced apoptosis by Mcl-1 degradation and its inhibition by Hsp70. | |
P478 | volume | 16 |
Q33813206 | A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci. |
Q39700222 | A novel BH3 mimetic S1 potently induces Bax/Bak-dependent apoptosis by targeting both Bcl-2 and Mcl-1. |
Q34412566 | Activation of caspase-9, but not caspase-2 or caspase-8, is essential for heat-induced apoptosis in Jurkat cells |
Q41865581 | BH3-only protein BIM mediates heat shock-induced apoptosis |
Q89565902 | Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma |
Q54326644 | Consequences of heat shock protein 72 (Hsp72) expression and activity on stress-induced apoptosis in CD30+ NPM-ALK+ anaplastic large-cell lymphomas. |
Q34973641 | Critical role for Gimap5 in the survival of mouse hematopoietic stem and progenitor cells |
Q53033302 | Evaluation of heat-shock protein A2 (HSPA2) in male rats before and after varicocele induction. |
Q50911306 | Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer. |
Q39269842 | Expression of miR-23a by apoptotic regulators in human cancer: A review |
Q28573772 | HSP70 protein promotes survival of C6 and U87 glioma cells by inhibition of ATF5 degradation |
Q100332790 | Heat Shock Proteins: Endogenous Modulators of Ferroptosis |
Q38892255 | Heat shock inhibition of CDK5 increases NOXA levels through miR-23a repression |
Q42959233 | Heat shock preconditioning protects against ER stress-induced apoptosis through the regulation of the BH3-only protein BIM. |
Q34533688 | Hsp70 architecture: the formation of novel polymeric structures of Hsp70.1 and Hsc70 after proteotoxic stress. |
Q38161378 | Inducible hsp70 in the regulation of cancer cell survival: analysis of chaperone induction, expression and activity |
Q40185074 | Mild thermotolerance induced at 40 °C protects cells against hyperthermia-induced pro-apoptotic changes in Bcl-2 family proteins. |
Q28740725 | Modulation of cellular Hsp72 levels in undifferentiated and neuron-like SH-SY5Y cells determines resistance to staurosporine-induced apoptosis |
Q28565594 | Nucleolin/C23 mediates the antiapoptotic effect of heat shock protein 70 during oxidative stress |
Q39443671 | Pim kinase inhibitors sensitize prostate cancer cells to apoptosis triggered by Bcl-2 family inhibitor ABT-737. |
Q90828550 | Pro-death signaling of cytoprotective heat shock factor 1: upregulation of NOXA leading to apoptosis in heat-sensitive cells. |
Q37092614 | Proteomic analysis of protein expression profiles during hyperthermia-induced apoptosis in Tca8113 cells |
Q35643014 | Quercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin's lymphoma B cells |
Q38214879 | Regulation of apoptosis by heat shock proteins |
Q37989861 | Role of the ubiquitin-proteasome system in nervous system function and disease: using C. elegans as a dissecting tool |
Q34521999 | Synergic antitumor effect of SKLB1002 and local hyperthermia in 4T1 and CT26. |
Q42508285 | The Role of Heat Shock Factors in Mammalian Spermatogenesis |
Q34662263 | The elimination of miR-23a in heat-stressed cells promotes NOXA-induced cell death and is prevented by HSP70 |
Q28388114 | The role of mitochondria-derived reactive oxygen species in hyperthermia-induced platelet apoptosis |
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