Properties of procoagulant platelets: defining and characterizing the subpopulation binding a functional prothrombinase

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Properties of procoagulant platelets: defining and characterizing the subpopulation binding a functional prothrombinase is …
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scholarly articleQ13442814

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P356DOI10.1161/ATVBAHA.110.216531
P932PMC publication ID3156579
P698PubMed publication ID21071689

P50authorBeth BouchardQ73182591
P2093author name stringJeremy P Wood
Ping Feng
Paula B Tracy
Ammon M Fager
P2860cites workTwo subpopulations of thrombin-activated platelets differ in their binding of the components of the intrinsic factor X-activating complex.Q54293957
Surface expression and functional characterization of alpha-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxinQ57591181
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Factor V is a substrate for the transamidase factor XIIIaQ69884610
Human prothrombinase complex assembly and function on isolated peripheral blood cell populationsQ70060804
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alpha-Thrombin-induced human platelet activation results solely from formation of a specific enzyme-substrate complexQ72808859
Effector cell protease receptor-1, a platelet activation-dependent membrane protein, regulates prothrombinase-catalyzed thrombin generationQ73182595
Simultaneous engagement of thrombin and Fc gamma RIIA receptors results in platelets expressing high levels of procoagulant proteinsQ77377400
Megakaryocytes endocytose and subsequently modify human factor V in vivo to form the entire pool of a unique platelet-derived cofactorQ81479235
Young thrombocytes initiate the formation of arterial thrombi in zebrafishQ30479622
Segregation of platelet aggregatory and procoagulant microdomains in thrombus formation: regulation by transient integrin activationQ30481898
Thrombin as a regulator of inflammation and reparative processes in tissuesQ34175987
Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially releasedQ34584213
Role of FcRgamma and factor XIIIA in coated platelet formationQ35848141
Coated-platelets: an emerging component of the procoagulant responseQ36272167
Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseasesQ37307308
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The regulation of clotting factorsQ41661751
Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surfaceQ43863360
Thrombospondin and fibrinogen bind serotonin-derivatized proteins on COAT-plateletsQ44155386
Unique in vivo modifications of coagulation factor V produce a physically and functionally distinct platelet-derived cofactor: characterization of purified platelet-derived factor V/VaQ44640434
Endocytosis of plasma-derived factor V by megakaryocytes occurs via a clathrin-dependent, specific membrane binding eventQ45302089
A subpopulation of platelets responds to thrombin- or SFLLRN-stimulation with binding sites for factor IXa.Q47976874
Evidence that differential packaging of the major platelet granule proteins von Willebrand factor and fibrinogen can support their differential release.Q50672582
Platelet factor Xa receptorQ52434023
Factor V activity of platelets: evidence for an activated factor V molecule and for a platelet activatorQ52475870
Thrombin and protease-activated receptors (PARs) in atherothrombosis.Q53497901
Platelet-derived factor Va/Va Leiden cofactor activities are sustained on the surface of activated platelets despite the presence of activated protein C.Q54138936
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)2400-2407
P577publication date2010-11-11
P1433published inArteriosclerosis, Thrombosis, and Vascular BiologyQ4797542
P1476titleProperties of procoagulant platelets: defining and characterizing the subpopulation binding a functional prothrombinase
P478volume30