Unique in vivo modifications of coagulation factor V produce a physically and functionally distinct platelet-derived cofactor: characterization of purified platelet-derived factor V/Va

scientific article published on 31 October 2003

Unique in vivo modifications of coagulation factor V produce a physically and functionally distinct platelet-derived cofactor: characterization of purified platelet-derived factor V/Va is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M308600200
P698PubMed publication ID14594814

P2093author name stringPaula B Tracy
Jay R Silveira
Weston R Gould
P2860cites workDynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brainQ24290716
Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeatsQ24310656
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Human coagluation factor V purification and thrombin-catalyzed activationQ37028310
Human plasma protein C: isolation, characterization, and mechanism of activation by alpha-thrombinQ37041393
Partial glycosylation at asparagine-2181 of the second C-type domain of human factor V modulates assembly of the prothrombinase complex.Q38320989
Thrombin-Catalyzed Activation of Recombinant Human Factor VQ41358432
Posttranslational sulfation of factor V is required for efficient thrombin cleavage and activation and for full procoagulant activityQ45873172
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The activation of bovine coagulation factor XQ55032927
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ProthrombinQ68236963
Expression and characterization of recombinant human factor V and a mutant lacking a major portion of the connecting regionQ68913493
Factor VQ70233554
Structural comparison of a 15 residue peptide from the V3 loop of HIV-1IIIb and an O-glycosylated analogueQ71548810
The Mechanism of Inactivation of Human Platelet Factor Va from Normal and Activated Protein C-resistant IndividualsQ72017113
Partial glycosylation of Asn2181 in human factor V as a cause of molecular and functional heterogeneity. Modulation of glycosylation efficiency by mutagenesis of the consensus sequence for N-linked glycosylationQ73082870
Inhibitory mechanism of the protein C pathway on tissue factor-induced thrombin generation. Synergistic effect in combination with tissue factor pathway inhibitorQ73144463
Protein C activation and factor Va inactivation on human umbilical vein endothelial cellsQ73965821
Identification and partial characterization of factor Va heavy chain kinase from human plateletsQ74393024
Proteolysis of factor V by cathepsin G and elastase indicates that cleavage at Arg1545 optimizes cofactor function by facilitating factor Xa bindingQ77153299
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)2383-2393
P577publication date2003-10-31
P1433published inJournal of Biological ChemistryQ867727
P1476titleUnique in vivo modifications of coagulation factor V produce a physically and functionally distinct platelet-derived cofactor: characterization of purified platelet-derived factor V/Va
P478volume279

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cites work (P2860)
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