MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-α during TLR4-induced gene reprogramming

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MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-α during TLR4-induced gene reprogramming is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1189/JLB.0211074
P932PMC publication ID3157899
P698PubMed publication ID21562054

P2093author name stringCharles E McCall
Mohamed El Gazzar
Tiefu Liu
Ashley Church
P2860cites workEndotoxin tolerance: new mechanisms, molecules and clinical significanceQ37603612
The systemic pro-inflammatory response in sepsisQ37763431
Gene-Specific Epigenetic Regulation in Serious Infections with Systemic InflammationQ37781968
Epigenetic silencing of tumor necrosis factor alpha during endotoxin toleranceQ40103534
Induction of RelB participates in endotoxin toleranceQ40236103
Circulating inflammatory mediators predict shock and mortality in febrile patients with microbial infectionQ40562200
Signal-specific and phosphorylation-dependent RelB degradation: a potential mechanism of NF-kappaB controlQ40758278
G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin toleranceQ43242886
MicroRNA-146a feedback inhibits RIG-I-dependent Type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2.Q54733079
Gene-specific control of inflammation by TLR-induced chromatin modificationsQ59065852
Systemic inflammatory response syndrome and compensatory anti-inflammatory response syndrome in sepsisQ84532452
Cell stress modulates the function of splicing regulatory protein RBM4 in translation controlQ24296006
Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cellsQ24297443
RNA-binding motif protein 4 translocates to cytoplasmic granules and suppresses translation via argonaute2 during muscle cell differentiationQ24321467
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responsesQ24670080
Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of careQ27860820
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?Q27860893
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Inhibition of translational initiation by Let-7 MicroRNA in human cellsQ28265842
The epidemiology of sepsis in the United States from 1979 through 2000Q29547760
Dynamic and selective nucleosome repositioning during endotoxin toleranceQ33569697
MicroRNAs distinguish translational from transcriptional silencing during endotoxin toleranceQ33967006
Facultative heterochromatin formation at the IL-1 beta promoter in LPS tolerance and sepsisQ34494297
Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responsesQ34626052
Rapid changes in microRNA-146a expression negatively regulate the IL-1beta-induced inflammatory response in human lung alveolar epithelial cells.Q34768042
Chronic sepsis mortality characterized by an individualized inflammatory responseQ35600970
A labile transcriptional repressor modulates endotoxin toleranceQ36364108
Epigenetic regulation of dendritic cell-derived interleukin-12 facilitates immunosuppression after a severe innate immune responseQ36445801
Gene silencing in severe systemic inflammationQ36719108
MicroRNAs and immunity: tiny players in a big fieldQ36739025
Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAsQ36990752
Micromanagement of the immune system by microRNAsQ37060274
microRNAs and the immune responseQ37178538
RBM4: a multifunctional RNA-binding proteinQ37250651
Expression of microRNA-146 in rheumatoid arthritis synovial tissueQ37359799
miR-146a is critical for endotoxin-induced tolerance: IMPLICATION IN INNATE IMMUNITY.Q37454160
The NF-kappaB factor RelB and histone H3 lysine methyltransferase G9a directly interact to generate epigenetic silencing in endotoxin toleranceQ37459848
P433issue3
P921main subjectmicroRNAQ310899
toll-like receptorQ408004
gene silencingQ1431332
P304page(s)509-519
P577publication date2011-05-11
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleMicroRNA-146a regulates both transcription silencing and translation disruption of TNF-α during TLR4-induced gene reprogramming
P478volume90

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