| scholarly article | Q13442814 |
| P2093 | author name string | Rajagopal N Aravalli | |
| P2860 | cites work | Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice | Q24170238 |
| The evolution of vertebrate Toll-like receptors | Q24530086 | ||
| Toll-like receptor signalling | Q24570126 | ||
| IL-10 inhibits miR-155 induction by toll-like receptors | Q24618242 | ||
| MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis | Q24654905 | ||
| Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model | Q24655262 | ||
| NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses | Q24670080 | ||
| Hepatitis C virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon and interleukin-6 | Q27472816 | ||
| Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog | Q27487860 | ||
| Alcoholic liver disease: pathogenesis and new therapeutic targets | Q27690220 | ||
| Pathogen recognition and innate immunity | Q27861084 | ||
| A human homologue of the Drosophila Toll protein signals activation of adaptive immunity | Q28131769 | ||
| Phylogenetic perspectives in innate immunity | Q28144345 | ||
| Microarray analysis of microRNA expression in hepatocellular carcinoma and non-tumorous tissues without viral hepatitis | Q94679839 | ||
| The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets. | Q37800217 | ||
| Tumor initiation and progression in hepatocellular carcinoma: risk factors, classification, and therapeutic targets | Q37800793 | ||
| Alcohol and hepatocyte-Kupffer cell interaction (review). | Q37862110 | ||
| Toll-like receptors in acute liver injury and regeneration | Q37877945 | ||
| Polymorphisms of toll-like receptors and their pathways in viral hepatitis | Q37891614 | ||
| Role of the microenvironment in hepatocellular carcinoma development and progression | Q37901677 | ||
| Role of Toll-like receptors in liver health and disease | Q37907346 | ||
| Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk | Q37923070 | ||
| Cancer-promoting tumor-associated macrophages: new vistas and open questions | Q37939626 | ||
| The tumor microenvironment in hepatocellular carcinoma (review). | Q37996920 | ||
| Overview and outlook of Toll-like receptor ligand-antigen conjugate vaccines. | Q38030027 | ||
| Innate immunity and HCV. | Q38051911 | ||
| Cancer-related microRNAs and their role as tumor suppressors and oncogenes in hepatocellular carcinoma | Q38066032 | ||
| Targeting the Toll-like receptor/interleukin 1 receptor pathway in human diseases: rational design of MyD88 inhibitors. | Q38089425 | ||
| Circulating markers for prognosis of hepatocellular carcinoma | Q38103946 | ||
| Development of MicroRNA Therapeutics for Hepatocellular Carcinoma | Q38719441 | ||
| Inflammatory stress exacerbates hepatic cholesterol accumulation via disrupting cellular cholesterol export | Q39440693 | ||
| Toll-like receptor ligands directly promote activated CD4+ T cell survival | Q39442360 | ||
| Role of toll-like receptors in changes in gene expression and NF-kappa B activation in mouse hepatocytes stimulated with lipopolysaccharide | Q39655506 | ||
| Stimulation of the interleukin-1 receptor and Toll-like receptor 2 inhibits hepatitis B virus replication in hepatoma cell lines in vitro | Q39790110 | ||
| Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells | Q39819720 | ||
| Hepatitis B virus induces expression of cholesterol metabolism-related genes via TLR2 in HepG2 cells | Q39883795 | ||
| Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma | Q39890346 | ||
| Transforming growth factor-beta1 and CD105 promote the migration of hepatocellular carcinoma-derived endothelium | Q39928929 | ||
| Molecular mechanisms of alcoholic fatty liver | Q37078754 | ||
| A review of the role of CpG oligodeoxynucleotides as toll-like receptor 9 agonists in prophylactic and therapeutic vaccine development in infectious diseases | Q37154750 | ||
| Molecular mechanisms of hepatocellular carcinoma | Q37323726 | ||
| miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses. | Q37354185 | ||
| MicroRNA involvement in hepatocellular carcinoma | Q37361575 | ||
| Modulation of TLR2 protein expression by miR-105 in human oral keratinocytes | Q37371743 | ||
| Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation | Q37399550 | ||
| The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: two triggers for one disease? | Q37480831 | ||
| Endotoxemia and gut barrier dysfunction in alcoholic liver disease | Q37539842 | ||
| Dendritic cells integrate signals from the tumor microenvironment to modulate immunity and tumor growth. | Q37602760 | ||
| Hallmarks of cancer: interactions with the tumor stroma. | Q37704659 | ||
| The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in mice | Q37728656 | ||
| New perspectives in MicroRNA regulation of innate immunity. | Q37755188 | ||
| New insights into the regulation of signalling by toll-like receptors and nod-like receptors. | Q37760999 | ||
| Toll-like receptors: a novel target for therapeutic intervention in intestinal and hepatic ischemia-reperfusion injury? | Q37766857 | ||
| Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases | Q28239642 | ||
| MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations | Q28277590 | ||
| The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults | Q28289939 | ||
| TLR signaling | Q28291637 | ||
| Hepatocellular carcinoma: epidemiology and molecular carcinogenesis | Q28306363 | ||
| The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein | Q28307210 | ||
| NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis | Q28384956 | ||
| Kupffer cell activation by lipopolysaccharide in rats: role for lipopolysaccharide binding protein and toll-like receptor 4 | Q28567351 | ||
| Hepatic expression patterns of inflammatory and immune response genes associated with obesity and NASH in morbidly obese patients | Q28748743 | ||
| Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21 | Q28975612 | ||
| MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response | Q29615493 | ||
| Hepatocellular carcinoma pathogenesis: from genes to environment | Q29615767 | ||
| Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection | Q29615959 | ||
| The impact of the gut microbiota on human health: an integrative view | Q29617446 | ||
| Mechanisms of hepatic fibrogenesis | Q29619336 | ||
| TLR4 enhances TGF-beta signaling and hepatic fibrosis | Q29620016 | ||
| Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis | Q33640296 | ||
| Toll-like receptor signaling inhibits hepatitis B virus replication in vivo. | Q33788761 | ||
| Pathogenesis of hepatitis B virus infection | Q33925491 | ||
| Serum microRNAs as biomarkers for hepatocellular carcinoma in Chinese patients with chronic hepatitis B virus infection | Q34103110 | ||
| Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation | Q34103235 | ||
| The association between Toll-like receptor 2 single-nucleotide polymorphisms and hepatocellular carcinoma susceptibility | Q34151951 | ||
| Isatoribine, an agonist of TLR7, reduces plasma virus concentration in chronic hepatitis C infection | Q34444955 | ||
| The role of microRNAs in liver cancer progression. | Q34543731 | ||
| miR-34 - a microRNA replacement therapy is headed to the clinic | Q34640230 | ||
| MicroRNA-146a is upregulated by and negatively regulates TLR2 signaling. | Q34701099 | ||
| Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival. | Q34742406 | ||
| Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells. | Q34753189 | ||
| Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation | Q34770928 | ||
| A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses | Q35147460 | ||
| MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-α during TLR4-induced gene reprogramming | Q35170010 | ||
| Tumour necrosis factor alpha: a potential target for the therapy of solid tumours. | Q35215812 | ||
| Kupffer cell suppression of CD8+ T cells in human hepatocellular carcinoma is mediated by B7-H1/programmed death-1 interactions | Q35422283 | ||
| Microbiota downregulates dendritic cell expression of miR-10a, which targets IL-12/IL-23p40. | Q35580720 | ||
| Human fatty liver disease: old questions and new insights | Q35588477 | ||
| Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice | Q35660292 | ||
| Differential contributions of C3, C5, and decay-accelerating factor to ethanol-induced fatty liver in mice. | Q35721145 | ||
| Complement and alcoholic liver disease: role of C1q in the pathogenesis of ethanol-induced liver injury in mice | Q35739330 | ||
| Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma | Q35740345 | ||
| Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice | Q35825858 | ||
| Aberrant methylation of SPARC in human hepatocellular carcinoma and its clinical implication | Q35929159 | ||
| NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications. | Q35931190 | ||
| Innate immunity in the liver | Q36036373 | ||
| Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2 | Q36042132 | ||
| The changing pattern of epidemiology in hepatocellular carcinoma | Q36084797 | ||
| Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis | Q36168809 | ||
| Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice | Q36243894 | ||
| Direct and indirect role of Toll-like receptors in T cell mediated immunity. | Q36286463 | ||
| B cell intrinsic TLR signals amplify but are not required for humoral immunity | Q36294387 | ||
| Discovering the first microRNA-targeted drug | Q36353486 | ||
| A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection | Q36372711 | ||
| Nonalcoholic fatty liver disease: from steatosis to cirrhosis | Q36382279 | ||
| Toll-like receptor signaling in the liver | Q36477368 | ||
| Interaction of Hepatitis C virus proteins with pattern recognition receptors | Q36513454 | ||
| Pattern recognition receptors: a contemporary view on liver diseases. | Q36548470 | ||
| Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by miR-132 and miR-212. | Q36553864 | ||
| Impaired toll-like receptor 3-mediated immune responses from macrophages of patients chronically infected with hepatitis C virus | Q36606736 | ||
| Discovery and development of sorafenib: a multikinase inhibitor for treating cancer. | Q36610990 | ||
| TLR signaling pathways: opportunities for activation and blockade in pursuit of therapy | Q36651901 | ||
| MicroRNA-92a negatively regulates Toll-like receptor (TLR)-triggered inflammatory response in macrophages by targeting MKK4 kinase | Q36685269 | ||
| Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling | Q36717761 | ||
| Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists | Q36811131 | ||
| Antagonism of the histamine H4 receptor reduces LPS-induced TNF production in vivo | Q36844550 | ||
| TLR2 is expressed on activated T cells as a costimulatory receptor | Q36853515 | ||
| Pathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer | Q36949589 | ||
| The current immune function of hepatic dendritic cells. | Q36988431 | ||
| Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b | Q37010874 | ||
| Differences in innate immune signaling between alcoholic and non-alcoholic steatohepatitis | Q37040722 | ||
| The role of microRNAs miR-200b and miR-200c in TLR4 signaling and NF-κB activation | Q37069797 | ||
| Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma | Q39958103 | ||
| Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment | Q40072016 | ||
| Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. | Q40092383 | ||
| Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation | Q40497000 | ||
| Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes | Q40845793 | ||
| Sensing bacterial flagellin by membrane and soluble orthologs of Toll-like receptor 5 in rainbow trout (Onchorhynchus mikiss). | Q42466865 | ||
| HCV-Related Proteins Activate Kupffer Cells Isolated from Human Liver Tissues | Q42999998 | ||
| The toll-like receptor 2 (TLR2) -196 to -174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C. | Q43036140 | ||
| Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers | Q43413375 | ||
| Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. | Q43845859 | ||
| Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific | Q44030856 | ||
| miR-181a and inflammation: miRNA homeostasis response to inflammatory stimuli in vivo | Q45095920 | ||
| The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88. | Q46367336 | ||
| IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis | Q46576855 | ||
| TLR agonists as vaccine adjuvants: comparison of CpG ODN and Resiquimod (R-848). | Q46635338 | ||
| TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain | Q46734348 | ||
| Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4. | Q46848107 | ||
| Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines. | Q47997828 | ||
| The burden of illness associated with hepatocellular carcinoma in the United States. | Q51124738 | ||
| Identification of metastasis-related microRNAs in hepatocellular carcinoma. | Q51897320 | ||
| Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. | Q51958786 | ||
| Additive effects of CpG ODN and R-848 as adjuvants on augmenting immune responses to HBsAg vaccination. | Q51973245 | ||
| Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. | Q52544717 | ||
| Seeking wisdom in innate immunity. | Q52553666 | ||
| The impact of CD4+ CD25+ T cells in the tumor microenvironment of hepatocellular carcinoma. | Q53214721 | ||
| Hepatic TLR2 & TLR4 expression correlates with hepatic inflammation and TNF-α in HCV & HCV/HIV infection. | Q54403253 | ||
| Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides. | Q54619338 | ||
| The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells. | Q55051405 | ||
| Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma | Q58619568 | ||
| TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity | Q62081996 | ||
| Inactivation of Kupffer cells prevents early alcohol-induced liver injury | Q72094198 | ||
| Antagonism of in vivo and ex vivo response to endotoxin by E5564, a synthetic lipid A analogue | Q73274386 | ||
| Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells | Q73322874 | ||
| The role of MAPK in Kupffer cell toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage | Q79373033 | ||
| Type 1 cytokine/chemokine production by mouse NK cells following activation of their TLR/MyD88-mediated pathways | Q79749601 | ||
| Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound | Q80428452 | ||
| Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients | Q80480802 | ||
| CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B HBV vaccine in healthy adults: a double-blind phase I/II study | Q81205526 | ||
| Toll-like receptors 1-9 are elevated in livers with fructose-induced hepatic steatosis | Q82144324 | ||
| Intratumoral neutrophils: a poor prognostic factor for hepatocellular carcinoma following resection | Q82641830 | ||
| Foxp3+ regulatory T cells are associated with the natural history of chronic hepatitis B and poor prognosis of hepatocellular carcinoma | Q82684267 | ||
| The inflammatory microenvironment of HCC - the plot becomes complex | Q83029773 | ||
| HBV-ISS (Dynavax) | Q83147755 | ||
| Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis | Q83181319 | ||
| Role of Foxp3-positive tumor-infiltrating lymphocytes in the histologic features and clinical outcomes of hepatocellular carcinoma | Q83740516 | ||
| Circulating Toll-like receptor (TLR) 2, TLR4, and regulatory T cells in patients with chronic hepatitis C | Q84076484 | ||
| Intratumoral regulatory T cells alone or in combination with cytotoxic T cells predict prognosis of hepatocellular carcinoma after resection | Q84373285 | ||
| Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes | Q84461047 | ||
| Strong CD8(+) T-cell responses against tumor-associated antigens prolong the recurrence-free interval after tumor treatment in patients with hepatocellular carcinoma | Q84948447 | ||
| Overexpression of Toll-like receptor 2/4 on monocytes modulates the activities of CD4(+)CD25(+) regulatory T cells in chronic hepatitis B virus infection | Q84961071 | ||
| P433 | issue | 43 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hepatocellular carcinoma | Q1148337 |
| P304 | page(s) | 7500-14 | |
| P577 | publication date | 2013-11-21 | |
| P1433 | published in | World Journal of Gastroenterology | Q15708885 |
| P1476 | title | Role of innate immunity in the development of hepatocellular carcinoma | |
| P478 | volume | 19 |
| Q38241837 | A clinical perspective on the role of chronic inflammation in gastrointestinal cancer |
| Q89753880 | A signature of 33 immune-related gene pairs predicts clinical outcome in hepatocellular carcinoma |
| Q36705808 | Cdx2 Expression and Intestinal Metaplasia Induced by H. pylori Infection of Gastric Cells Is Regulated by NOD1-Mediated Innate Immune Responses. |
| Q26773212 | Effects of Alcohol on Tumor Growth, Metastasis, Immune Response, and Host Survival |
| Q43072520 | Epithelium-Specific ETS (ESE)-1 upregulated GP73 expression in hepatocellular carcinoma cells |
| Q57008273 | Functional Polymorphisms in Are Related to Hepatocellular Carcinoma Risk in Chinese Population |
| Q33827475 | Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma |
| Q40238231 | Hepatic expression of oncogenes Bmi1 and Dkk1 is up-regulated in hepatitis B virus surface antigen-transgenic mice and can be induced by treatment with HBV particles or lipopolysaccharides in vitro |
| Q26745984 | Hepatitis C Virus Infection Induces Autophagy as a Prosurvival Mechanism to Alleviate Hepatic ER-Stress Response |
| Q39144327 | Immune-Mediated Therapies for Liver Cancer. |
| Q26795411 | Immunology of hepatocellular carcinoma |
| Q47154433 | Impact of cavitron ultrasonic surgical aspirator (CUSA) and bipolar radiofrequency device (Habib-4X) based hepatectomy for hepatocellular carcinoma on tumour recurrence and disease-free survival. |
| Q35092312 | Impaired function of CD4+ T follicular helper (Tfh) cells associated with hepatocellular carcinoma progression |
| Q91632122 | Importance of genetic polymorphisms in liver transplantation outcomes |
| Q35513609 | Inhibition of diethylnitrosamine-initiated alcohol-promoted hepatic inflammation and precancerous lesions by flavonoid luteolin is associated with increased sirtuin 1 activity in mice |
| Q26770029 | Innate immunity and hepatocarcinoma: Can toll-like receptors open the door to oncogenesis? |
| Q38752619 | Kruppel-like factor 6 suppresses growth and invasion of hepatocellular carcinoma cells in vitro and in vivo |
| Q42705659 | Nucleic Acid Sensors Involved in the Recognition of HBV in the Liver-Specific in vivo Transfection Mouse Models-Pattern Recognition Receptors and Sensors for HBV |
| Q58556622 | Preclinical and Clinical Therapeutic Strategies Affecting Tumor-Associated Macrophages in Hepatocellular Carcinoma |
| Q55052958 | Stevia Prevents Acute and Chronic Liver Injury Induced by Carbon Tetrachloride by Blocking Oxidative Stress through Nrf2 Upregulation. |
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