| scholarly article | Q13442814 |
| P50 | author | Marco Osterwalder | Q58887373 |
| Robert Ivánek | Q63681463 | ||
| Vincent M. Christoffels | Q70803769 | ||
| Axel Visel | Q37374404 | ||
| Javier Lopez-Rios | Q42334697 | ||
| Rolf Zeller | Q43082047 | ||
| P2093 | author name string | Malak Shoukry | |
| Christian Beisel | |||
| Dario Speziale | |||
| Manuel Kohler | |||
| Rajiv Mohan | |||
| Suzie J Scales | |||
| Xiaohui Wen | |||
| P2860 | cites work | Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb | Q22253250 |
| Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesis | Q24596162 | ||
| Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities | Q24651500 | ||
| Retinoic acid promotes limb induction through effects on body axis extension but is unnecessary for limb patterning | Q24658041 | ||
| Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling | Q24672542 | ||
| VISTA Enhancer Browser--a database of tissue-specific human enhancers | Q24676452 | ||
| A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly | Q28184095 | ||
| Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function | Q28209365 | ||
| A re-examination of proximodistal patterning during vertebrate limb development | Q28216626 | ||
| The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer | Q28216746 | ||
| Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly | Q28260017 | ||
| Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities | Q28277481 | ||
| Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development | Q28473604 | ||
| Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning | Q28504770 | ||
| Hand2 controls osteoblast differentiation in the branchial arch by inhibiting DNA binding of Runx2 | Q28506661 | ||
| Embryonic retinoic acid synthesis is required for forelimb growth and anteroposterior patterning in the mouse | Q44064037 | ||
| Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes | Q44530039 | ||
| Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs. | Q50651259 | ||
| Formation of proximal and anterior limb skeleton requires early function of Irx3 and Irx5 and is negatively regulated by Shh signaling. | Q50670906 | ||
| Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function. | Q52046374 | ||
| Tbx3 can alter limb position along the rostrocaudal axis of the developing embryo. | Q52054111 | ||
| Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb. | Q52059096 | ||
| Distribution of polarizing activity and potential for limb formation in mouse and chick embryos and possible relationships to polydactyly. | Q52165848 | ||
| The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development. | Q52168461 | ||
| HoxB6-Cre transgenic mice express Cre recombinase in extra-embryonic mesoderm, in lateral plate and limb mesoderm and at the midbrain/hindbrain junction. | Q52169993 | ||
| The prechordal midline of the chondrocranium is defective in Goosecoid-1 mouse mutants | Q57385014 | ||
| Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome | Q28509247 | ||
| Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation | Q28512034 | ||
| GATA6 is a crucial regulator of Shh in the limb bud | Q28538554 | ||
| Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning | Q28584721 | ||
| Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression | Q28585137 | ||
| Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND | Q28592248 | ||
| Development of five digits is controlled by a bipartite long-range cis-regulator | Q28660338 | ||
| Network motifs: theory and experimental approaches | Q29615325 | ||
| Uncoupling Sonic Hedgehog Control of Pattern and Expansion of the Developing Limb Bud | Q30039622 | ||
| Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1. | Q30496250 | ||
| Fine tuning of craniofacial morphology by distant-acting enhancers | Q30576356 | ||
| Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development | Q33567281 | ||
| Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin | Q33885423 | ||
| Evolution of mouse T-box genes by tandem duplication and cluster dispersion. | Q33968344 | ||
| Dual RMCE for efficient re-engineering of mouse mutant alleles | Q34144198 | ||
| Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1. | Q34342187 | ||
| Vertebrate limb bud development: moving towards integrative analysis of organogenesis | Q35013365 | ||
| GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis | Q35801438 | ||
| Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb | Q36021697 | ||
| Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation. | Q36916855 | ||
| A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb | Q36919931 | ||
| Hand factors as regulators of cardiac morphogenesis and implications for congenital heart defects | Q37861072 | ||
| Human limb abnormalities caused by disruption of hedgehog signaling | Q38005566 | ||
| Transcription factors: from enhancer binding to developmental control | Q38032407 | ||
| Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb | Q38274731 | ||
| Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation | Q39739721 | ||
| Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb | Q42089007 | ||
| Gene expression profiling of the forming atrioventricular node using a novel tbx3-based node-specific transgenic reporter | Q42623619 | ||
| FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds | Q42629225 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 13 | |
| P304 | page(s) | 345-357 | |
| P577 | publication date | 2014-11-10 | |
| P1433 | published in | Developmental Cell | Q1524277 |
| P1476 | title | HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme | |
| P478 | volume | 31 |
| Q35961632 | A shift in anterior-posterior positional information underlies the fin-to-limb evolution |
| Q37120535 | A unique stylopod patterning mechanism by Shox2-controlled osteogenesis. |
| Q35950995 | Anteroposterior Limb Skeletal Patterning Requires the Bifunctional Action of SWI/SNF Chromatin Remodeling Complex in Hedgehog Pathway |
| Q39125945 | Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin folding |
| Q41189372 | Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis. |
| Q46270237 | Developmental, genetic, and genomic insights into the evolutionary loss of limbs in snakes. |
| Q50114986 | Enhancer redundancy provides phenotypic robustness in mammalian development |
| Q37086538 | Exclusion of Dlx5/6 expression from the distal-most mandibular arches enables BMP-mediated specification of the distal cap. |
| Q38611761 | Fins into limbs: Recent insights from sarcopterygian fish. |
| Q28552221 | Gata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb Development |
| Q100418580 | Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks |
| Q42776614 | HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development |
| Q56978269 | Hand Factors in Cardiac Development |
| Q92217593 | Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming |
| Q39224440 | Hand2 inhibits kidney specification while promoting vein formation within the posterior mesoderm |
| Q38562018 | How the embryo makes a limb: determination, polarity and identity |
| Q36173741 | Identification and functional characterization of novel transcriptional enhancers involved in regulating human GLI3 expression during early development. |
| Q39119924 | John Saunders' ZPA, Sonic hedgehog and digit identity - How does it really all work? |
| Q55691558 | LHX2 Mediates the FGF-to-SHH Regulatory Loop during Limb Development. |
| Q41577826 | Limb-Enhancer Genie: An accessible resource of accurate enhancer predictions in the developing limb. |
| Q57186379 | Loss of Tbx3 in murine neural crest reduces enteric glia and causes cleft palate, but does not influence heart development or bowel transit |
| Q63681805 | Molecular signatures identify immature mesenchymal progenitors in early mouse limb buds that respond differentially to morphogen signaling |
| Q35549367 | Sall4-Gli3 system in early limb progenitors is essential for the development of limb skeletal elements. |
| Q92832291 | Self-organized formation of developing appendages from murine pluripotent stem cells |
| Q37027898 | Specification of jaw identity by the Hand2 transcription factor |
| Q41447969 | The Conserved Sonic Hedgehog Limb Enhancer Consists of Discrete Functional Elements that Regulate Precise Spatial Expression |
| Q35936973 | The Transcription Factor Hand1 Is Involved In Runx2-Ihh-Regulated Endochondral Ossification |
| Q27301427 | The bHLH Transcription Factor Hand Regulates the Expression of Genes Critical to Heart and Muscle Function in Drosophila melanogaster |
| Q81446772 | The roles and regulation of TBX3 in development and disease. |
| Q38742828 | The two domain hypothesis of limb prepattern and its relevance to congenital limb anomalies |
| Q64096155 | Tissue specific human fibroblast differential expression based on RNAsequencing analysis |
| Q48230461 | Upstream regulation for initiation of restricted Shh expression in the chick limb bud. |
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