A multifunctional plasmid-encoded replication initiation protein both recruits and positions an active helicase at the replication origin

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A multifunctional plasmid-encoded replication initiation protein both recruits and positions an active helicase at the replication origin is …
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scholarly articleQ13442814

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P819ADS bibcode2003PNAS..100.8692J
P356DOI10.1073/PNAS.1532393100
P932PMC publication ID166374
P698PubMed publication ID12835421
P5875ResearchGate publication ID10683900

P2093author name stringYong Jiang
Marcin Pacek
Igor Konieczny
Aresa Toukdarian
Donald R Helinski
P2860cites workThe bacterial replicative helicase DnaB evolved from a RecA duplicationQ28143220
Mechanistic aspects of DnaA-RepA interaction as revealed by yeast forward and reverse two-hybrid analysisQ28345862
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Mechanistic studies of initiator-initiator interaction and replication initiationQ33889438
Open-complex formation by the host initiator, DnaA, at the origin of P1 plasmid replicationQ34069162
The dnaA protein complex with the E. coli chromosomal replication origin (oriC) and other DNA sites.Q34245423
A broad host range replicon with different requirements for replication initiation in three bacterial speciesQ34769747
Mechanism of recruitment of DnaB helicase to the replication origin of the plasmid pSC101.Q34791013
The bacterial replication initiator DnaA. DnaA and oriC, the bacterial mode to initiate DNA replicationQ34987457
Induction of structural changes in the bovine papillomavirus type 1 origin of replication by the viral E1 and E2 proteinsQ35750818
Cryptic single-stranded-DNA binding activities of the phage lambda P and Escherichia coli DnaC replication initiation proteins facilitate the transfer of E. coli DnaB helicase onto DNAQ35989806
Unwinding of the box I element of a herpes simplex virus type 1 origin by a complex of the viral origin binding protein, single-strand DNA binding protein, and single-stranded DNA.Q36071486
Broad-host-range properties of plasmid RK2: importance of overlapping genes encoding the plasmid replication initiation protein TrfA.Q36154008
EBNA1 distorts oriP, the Epstein-Barr virus latent replication originQ36693870
The replication initiator protein pi of the plasmid R6K specifically interacts with the host-encoded helicase DnaB.Q37591002
Copy-up mutants of the plasmid RK2 replication initiation protein are defective in coupling RK2 replication originsQ37661651
Binding and unwinding--how T antigen engages the SV40 origin of DNA replicationQ37870911
Monomer/dimer ratios of replication protein modulate the DNA strand-opening in a replication originQ38303508
DnaA protein directs the binding of DnaB protein in initiation of DNA replication in Escherichia coliQ38311001
Requirements for and regulation of origin opening of plasmid P1.Q38333505
The plasmid RK2 initiation protein binds to the origin of replication as a monomerQ38360196
Localized DNA melting and structural pertubations in the origin of replication, oriC, of Escherichia coli in vitro and in vivoQ41081137
Fine balance in the regulation of DnaB helicase by DnaC protein in replication in Escherichia coliQ41136317
Host-dependent requirement for specific DnaA boxes for plasmid RK2 replicationQ41681231
Interactions of DnaA proteins from distantly related bacteria with the replication origin of the broad host range plasmid RK2.Q41728432
Role of TrfA and DnaA proteins in origin opening during initiation of DNA replication of the broad host range plasmid RK2.Q42661197
Interactions of plasmid-encoded replication initiation proteins with the origin of DNA replication in the broad host range plasmid RK2.Q43658211
The localized melting of mini-F origin by the combined action of the mini-F initiator protein (RepE) and HU and DnaA of Escherichia coliQ44029616
Duplex opening by dnaA protein at novel sequences in initiation of replication at the origin of the E. coli chromosomeQ44347022
Replication origin of the broad host range plasmid RK2. Positioning of various motifs is critical for initiation of replication.Q45999258
Helicase delivery and activation by DnaA and TrfA proteins during the initiation of replication of the broad host range plasmid RK2.Q46088788
The sequence encoding the 43-kilodalton trfA protein is required for efficient replication or maintenance of minimal RK2 replicons in Pseudomonas aeruginosaQ46441306
In vitro assembly of a prepriming complex at the origin of the Escherichia coli chromosome.Q54763210
Extensive unwinding of the plasmid template during staged enzymatic initiation of DNA replication from the origin of the Escherichia coli chromosome.Q54781669
Helicase action of dnaB protein during replication from the Escherichia coli chromosomal origin in vitroQ61959649
The Escherichia coli dnaC gene product. II. Purification, physical properties, and role in replicationQ67235537
Initiation protein induced helix destabilization at the lambda origin: a prepriming step in DNA replicationQ69820081
Analysis of the trfA region of broad host-range plasmid RK2 by transposon mutagenesis and identification of polypeptide productsQ70214289
Proteins encoded by the trans-acting replication and maintenance regions of broad host range plasmid RK2Q70334855
DnaA box sequences as the site for helicase delivery during plasmid RK2 replication initiation in Escherichia coliQ73794048
P433issue15
P407language of work or nameEnglishQ1860
P304page(s)8692-8697
P577publication date2003-06-30
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleA multifunctional plasmid-encoded replication initiation protein both recruits and positions an active helicase at the replication origin
P478volume100

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cites work (P2860)
Q46167633A specific region in the N terminus of a replication initiation protein of plasmid RK2 is required for recruitment of Pseudomonas aeruginosa DnaB helicase to the plasmid origin
Q34233413AT-rich region and repeated sequences - the essential elements of replication origins of bacterial replicons.
Q36440552Bacteriophage replication modules
Q38347023Biochemical investigations of control of replication initiation of plasmid R6K.
Q26781545Choosing a suitable method for the identification of replication origins in microbial genomes
Q42064722Conformation of a plasmid replication initiator protein affects its proteolysis by ClpXP system
Q40778914Evolved plasmid-host interactions reduce plasmid interference cost.
Q28270244Mechanisms of, and barriers to, horizontal gene transfer between bacteria
Q35946244Plasmid replication initiator interactions with origin 13-mers and polymerase subunits contribute to strand-specific replisome assembly
Q60953419Reconsidering plasmid maintenance factors for computational plasmid design
Q34209486Replication initiation at the Escherichia coli chromosomal origin
Q26738704Replisome Assembly at Bacterial Chromosomes and Iteron Plasmids
Q35806093Roles of long and short replication initiation proteins in the fate of IncP-1 plasmids.
Q34592627Shifts in the host range of a promiscuous plasmid through parallel evolution of its replication initiation protein

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