The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release

scientific article

The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M114.592717
P932PMC publication ID4358283
P698PubMed publication ID25586178

P2093author name stringTakeshi Hamada
Naoaki Saito
Corinne Dupuy
Thomas L Leto
Miklós Geiszt
Takehiko Ueyama
Megumi Sakuma
Yuzuru Ninoyu
P2860cites workTransient congenital hypothyroidism caused by biallelic mutations of the dual oxidase 2 gene in Japanese patients detected by a neonatal screening programQ46395486
Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalentQ47208280
Negative charges in the flexible N-terminal domain of Rho GDP-dissociation inhibitors (RhoGDIs) regulate the targeting of the RhoGDI-Rac1 complex to membranesQ47849199
Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnasQ22010938
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase familyQ22254073
Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activityQ24306096
Caenorhabditis elegans and human dual oxidase 1 (DUOX1) "peroxidase" domains: insights into heme binding and catalytic activityQ24651445
A novel host defense system of airways is defective in cystic fibrosisQ24657774
Detection of superoxide anion and hydrogen peroxide production by cellular NADPH oxidasesQ27022012
Physiological and pathological functions of NADPH oxidases during myocardial ischemia-reperfusionQ27027209
Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defenseQ28181893
Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5Q28190953
A direct role for dual oxidase in Drosophila gut immunityQ28280565
Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen speciesQ28282131
Dual oxidase2 is expressed all along the digestive tractQ28297773
Congenital hypothyroidism, dwarfism, and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox2Q28507182
Mice deficient in dual oxidase maturation factors are severely hypothyroidQ28512965
A regulated adaptor function of p40phox: distinct p67phox membrane targeting by p40phox and by p47phoxQ30478913
Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidasesQ30491877
Cloning of tissue-specific genes using serial analysis of gene expression and a novel computational substraction approach.Q30997314
Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymesQ33290000
The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4Q34787163
A single copy of the recently identified dual oxidase maturation factor (DUOXA) 1 gene produces only mild transient hypothyroidism in a patient with a novel biallelic DUOXA2 mutation and monoallelic DUOXA1 deletionQ34894388
Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidismQ36459926
The expanding role of NADPH oxidases in health and disease: no longer just agents of death and destructionQ36501615
Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generationQ37139797
Dual oxidases control release of hydrogen peroxide by the gastric epithelium to prevent Helicobacter felis infection and inflammation in miceQ37248764
Nox enzymes in allergic airway inflammationQ37852399
Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signalingQ38155661
Cell-free NADPH oxidase activation assays: "in vitro veritas".Q42229430
Urothelial cells produce hydrogen peroxide through the activation of Duox1.Q42781454
Structural stability and heme binding potential of the truncated human dual oxidase 2 (DUOX2) peroxidase domain.Q42824848
The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.Q43607245
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectreactive oxygen speciesQ424361
P304page(s)6495-6506
P577publication date2015-01-13
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release
P478volume290

Reverse relations

cites work (P2860)
Q88956461Antimicrobial actions of dual oxidases and lactoperoxidase
Q42152446Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation
Q36574640Enzymatic regulation and functional relevance of NOX5
Q26799545Genetic disorders coupled to ROS deficiency
Q46280862Lung Ischaemia-Reperfusion Injury: The Role of Reactive Oxygen Species
Q38833270NADPH oxidases: new actors in thyroid cancer?
Q38382136Nox5 stability and superoxide production is regulated by C-terminal binding of Hsp90 and CO-chaperones.
Q39348472Paradoxical roles of dual oxidases in cancer biology.
Q92079223Pharmacological characterization of the seven human NOX isoforms and their inhibitors
Q64244340Rho-Family Small GTPases: From Highly Polarized Sensory Neurons to Cancer Cells
Q99418934Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation
Q90077310The Dual Oxidase Duox2 stabilized with DuoxA2 in an enzymatic complex at the surface of the cell produces extracellular H2O2 able to induce DNA damage in an inducible cellular model

Search more.