| scholarly article | Q13442814 |
| P356 | DOI | 10.4049/JIMMUNOL.1100088 |
| P8608 | Fatcat ID | release_rhfp7vz64ne6xfntpvmnexrkpu |
| P932 | PMC publication ID | 3159690 |
| P698 | PubMed publication ID | 21813776 |
| P5875 | ResearchGate publication ID | 51544660 |
| P50 | author | John Cambier | Q28112855 |
| Laurel L Lenz | Q84670844 | ||
| Lei Jin | Q42864061 | ||
| P2093 | author name string | Anne-Laure Perraud | |
| Bicheng Zhang | |||
| Krista K Hill | |||
| Heather Knowles | |||
| Jennifer Mogan | |||
| Holly Filak | |||
| P2860 | cites work | IFI16 is an innate immune sensor for intracellular DNA | Q24301720 |
| The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA | Q24306840 | ||
| ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization | Q24310014 | ||
| STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling | Q24336398 | ||
| c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response | Q24616827 | ||
| A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP | Q24642631 | ||
| Roles of cyclic diguanylate in the regulation of bacterial pathogenesis | Q24656979 | ||
| Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication | Q28264386 | ||
| Type I interferon: friend or foe? | Q28293186 | ||
| STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity | Q28509328 | ||
| The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses | Q29614469 | ||
| Bacterial c-di-GMP is an immunostimulatory molecule | Q44754791 | ||
| Expression of the p60 autolysin enhances NK cell activation and is required for listeria monocytogenes expansion in IFN-gamma-responsive mice | Q79718033 | ||
| Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways | Q80345055 | ||
| Recognition of cytosolic DNA activates an IRF3-dependent innate immune response | Q29616156 | ||
| The AIM2 inflammasome is critical for innate immunity to Francisella tularensis | Q29622833 | ||
| Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes | Q33422966 | ||
| Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma | Q33656158 | ||
| Cellular reactive oxygen species inhibit MPYS induction of IFNβ | Q33775473 | ||
| A fluorescence reporter model defines "Tip-DCs" as the cellular source of interferon β in murine listeriosis | Q33778732 | ||
| Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population | Q33815694 | ||
| Production of IFN-β during Listeria monocytogenes infection is restricted to monocyte/macrophage lineage | Q33873396 | ||
| Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections | Q33887598 | ||
| Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. | Q34006614 | ||
| The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides | Q34151349 | ||
| Innate recognition of bacteria by a macrophage cytosolic surveillance pathway | Q34161941 | ||
| Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. | Q34163303 | ||
| Antagonistic crosstalk between type I and II interferons and increased host susceptibility to bacterial infections | Q34215390 | ||
| Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2. | Q34361030 | ||
| Listeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunity | Q34796825 | ||
| Anti-cytokine therapeutics and infections | Q35134693 | ||
| Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes | Q35876024 | ||
| Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha /beta | Q35894501 | ||
| C-di-GMP: the dawning of a novel bacterial signalling system | Q36207912 | ||
| The yin and yang of type I interferon activity in bacterial infection | Q36234715 | ||
| Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes | Q36399578 | ||
| Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to Listeria infection. | Q36399581 | ||
| Type I interferon production enhances susceptibility to Listeria monocytogenes infection | Q36399599 | ||
| MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals | Q36845998 | ||
| c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection. | Q37109444 | ||
| Critical functions of priming and lysosomal damage for NLRP3 activation | Q37485683 | ||
| Incidence and nature of infectious disease in patients treated with anti-TNF agents | Q37589000 | ||
| The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis | Q38304495 | ||
| Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes. | Q39689997 | ||
| 3',5'-Cyclic diguanylic acid (c-di-GMP) inhibits basal and growth factor-stimulated human colon cancer cell proliferation. | Q40456655 | ||
| Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome | Q42785062 | ||
| Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria | Q43596491 | ||
| Cutting edge: a murine, IL-12-independent pathway of IFN-gamma induction by gram-negative bacteria based on STAT4 activation by Type I IFN and IL-18 signaling | Q44092276 | ||
| TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection | Q44308127 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2595-2601 | |
| P577 | publication date | 2011-08-03 | |
| P1433 | published in | Journal of Immunology | Q3521441 |
| P1476 | title | MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP | |
| P478 | volume | 187 |
| Q34303159 | 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential |
| Q48182923 | A Comparison of Oral and Intravenous Mouse Models of Listeriosis. |
| Q38712891 | A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1. |
| Q47573396 | A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination |
| Q47631823 | ALK is a therapeutic target for lethal sepsis. |
| Q40438700 | AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling |
| Q38105072 | Age-dependent differences in systemic and cell-autonomous immunity to L. monocytogenes |
| Q38788154 | Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells |
| Q35936773 | Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling |
| Q24338728 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling |
| Q35903465 | Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production |
| Q57038239 | B Cell-Intrinsic STING Signaling Triggers Cell Activation, Synergizes with B Cell Receptor Signals, and Promotes Antibody Responses |
| Q46401306 | B Cells Producing Type I Interferon Modulate Macrophage Polarization in Tuberculosis |
| Q34414006 | Bacterial programming of host responses: coordination between type I interferon and cell death |
| Q28081450 | Bacterial recognition pathways that lead to inflammasome activation |
| Q39254592 | Both STING and MAVS fish orthologs contribute to the induction of interferon mediated by RIG-I |
| Q28555172 | Cell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes Infection |
| Q91215987 | Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression |
| Q33565957 | Crosstalk Between Apoptosis and Autophagy: Environmental Genotoxins, Infection, and Innate Immunity |
| Q27681354 | Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP |
| Q36143536 | Crystallization studies of the murine c-di-GMP sensor protein STING. |
| Q91729315 | Cyclic Dimeric Guanosine Monophosphate: Activation and Inhibition of Innate Immune Response |
| Q40339226 | Cyclic Dinucleotides in the Scope of the Mammalian Immune System |
| Q37425019 | Cyclic di-AMP Released from Staphylococcus aureus Biofilm Induces a Macrophage Type I Interferon Response |
| Q37545670 | Cyclic di-AMP impairs potassium uptake mediated by a cyclic di-AMP binding protein in Streptococcus pneumoniae. |
| Q38118107 | Cyclic di-AMP: another second messenger enters the fray |
| Q24338485 | Cyclic di-GMP sensing via the innate immune signaling protein STING |
| Q37597305 | Cyclic dinucleotides and the innate immune response |
| Q37252429 | Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome |
| Q26852473 | Cytosolic sensing of viruses |
| Q36182882 | Decreased Expression of TMEM173 Predicts Poor Prognosis in Patients with Hepatocellular Carcinoma |
| Q33870379 | Deletion of the cyclic di-AMP phosphodiesterase gene (cnpB) in Mycobacterium tuberculosis leads to reduced virulence in a mouse model of infection |
| Q34614798 | Detection of cyclic di-AMP using a competitive ELISA with a unique pneumococcal cyclic di-AMP binding protein |
| Q26849516 | Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections |
| Q92712450 | Early Transcriptional Signature in Dendritic Cells and the Induction of Protective T Cell Responses Upon Immunization With VLPs Containing TLR Ligands-A Role for CCL2 |
| Q38909303 | Francisella Inflammasomes: Integrated Responses to a Cytosolic Stealth Bacterium. |
| Q35739643 | Functional Analysis of a c-di-AMP-specific Phosphodiesterase MsPDE from Mycobacterium smegmatis |
| Q38705916 | Grass Carp Reovirus VP41 Targets Fish MITA To Abrogate the Interferon Response |
| Q30537996 | Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells |
| Q39899771 | Identification and expression analysis of the sting gene, a sensor of viral DNA, in common carp Cyprinus carpio. |
| Q39077769 | Identification of a negative feedback loop between cyclic di-GMP-induced levels of IFI16 and p202 cytosolic DNA sensors and STING. |
| Q57459224 | Immature lung TNFR2 conventional DC 2 subpopulation activates moDCs to promote cyclic di-GMP mucosal adjuvant responses in vivo |
| Q38109307 | Immune sensing of DNA |
| Q96126440 | Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity |
| Q38590737 | Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses. |
| Q92110459 | Innate Immune Recognition: An Issue More Complex Than Expected |
| Q45715422 | Innate Immune Recognition: Implications for the Interaction of Francisella tularensis with the Host Immune System |
| Q40036388 | Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence. |
| Q54471031 | Innate sensing of bacterial cyclic dinucleotides: more than just STING. |
| Q28081406 | International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease |
| Q35612948 | Intracellular Concentrations of Borrelia burgdorferi Cyclic Di-AMP Are Not Changed by Altered Expression of the CdaA Synthase |
| Q37627133 | Intracellular pathogen detection by RIG-I-like receptors |
| Q33704771 | Involvement of GATA1 and Sp3 in the activation of the murine STING gene promoter in NIH3T3 cells |
| Q41950656 | Keeping your armour intact: how HIV-1 evades detection by the innate immune system: HIV-1 capsid controls detection of reverse transcription products by the cytosolic DNA sensor cGAS. |
| Q40673144 | LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner |
| Q37601458 | Listeria monocytogenes MDR transporters are involved in LTA synthesis and triggering of innate immunity during infection. |
| Q34324531 | Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway |
| Q38220292 | MITA/STING: a central and multifaceted mediator in innate immune response |
| Q54487555 | MPYS/STING-mediated TNF-α, not type I IFN, is essential for the mucosal adjuvant activity of (3'-5')-cyclic-di-guanosine-monophosphate in vivo. |
| Q37709077 | Mechanisms of transcriptional activation of the stimulator of interferon genes by transcription factors CREB and c-Myc |
| Q38315636 | Microbial DNA recognition by cGAS-STING and other sensors in dendritic cells in inflammatory bowel diseases |
| Q59350249 | Molecular Characterization, Expression and Functional Analysis of Chicken |
| Q38082423 | Molecular basis of DNA recognition in the immune system |
| Q30275022 | Monophosphoryl Lipid A Enhances Efficacy of a Francisella tularensis LVS-Catanionic Nanoparticle Subunit Vaccine against F. tularensis Schu S4 Challenge by Augmenting both Humoral and Cellular Immunity |
| Q31058151 | Mycobacterium tuberculosis Rv3586 (DacA) is a diadenylate cyclase that converts ATP or ADP into c-di-AMP. |
| Q28975619 | NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING |
| Q99616121 | Notch signaling protects CD4 T cells from STING-mediated apoptosis during acute systemic inflammation |
| Q36586267 | Nuclease-Resistant c-di-AMP Derivatives That Differentially Recognize RNA and Protein Receptors |
| Q39011657 | Nucleic acid sensing and innate immunity: signaling pathways controlling viral pathogenesis and autoimmunity |
| Q37559665 | Post-translational regulation of inflammasomes |
| Q37690959 | Promising Targets for Cancer Immunotherapy: TLRs, RLRs, and STING-Mediated Innate Immune Pathways |
| Q38752535 | RIG-I-Mediated STING Upregulation Restricts Herpes Simplex Virus 1 Infection |
| Q29871504 | RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanisms |
| Q89998225 | RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation |
| Q39000597 | Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production |
| Q28118888 | Rat and human STINGs profile similarly towards anticancer/antiviral compounds |
| Q21131298 | Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination |
| Q39360861 | Regulating STING in health and disease |
| Q37162518 | Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1. |
| Q36866528 | Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response |
| Q59350771 | Role of the cGAS-STING pathway in cancer development and oncotherapeutic approaches |
| Q36288074 | STING activator c-di-GMP enhances the anti-tumor effects of peptide vaccines in melanoma-bearing mice |
| Q34317532 | STING and the innate immune response to nucleic acids in the cytosol |
| Q50292080 | STING binds c-di-GMP |
| Q100395390 | STING regulates BCR signaling in normal and malignant B cells |
| Q38711931 | STING-IRF3 Triggers Endothelial Inflammation in Response to Free Fatty Acid-Induced Mitochondrial Damage in Diet-Induced Obesity |
| Q36872696 | STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection. |
| Q35082223 | STING-dependent type I IFN production inhibits cell-mediated immunity to Listeria monocytogenes |
| Q34326002 | STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration. |
| Q90176744 | Selective Loss of Responsiveness to Exogenous but Not Endogenous Cyclic-Dinucleotides in Mice Expressing STING-R231H |
| Q40119404 | Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis |
| Q26799867 | Sensors of Infection: Viral Nucleic Acid PRRs in Fish |
| Q35581615 | Single amino acid change in STING leads to constitutive active signaling |
| Q21132463 | Single nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotides |
| Q27679046 | Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding |
| Q90660461 | Sufficiency of CD40 activation and immune checkpoint blockade for T cell priming and tumor immunity |
| Q91996200 | T cell fate following Salmonella infection is determined by a STING-IRF1 signaling axis in mice |
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| Q47558454 | The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires' disease in humans. |
| Q36817378 | The cyclic AMP signaling pathway: Exploring targets for successful drug discovery (Review). |
| Q28510485 | The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response |
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