The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides

scientific article

The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00999-10
P932PMC publication ID3028833
P698PubMed publication ID21098106

P50authorDaniel A. PortnoyQ26737169
Mamoru HyodoQ56259636
John-Demian SauerQ56433698
P2093author name stringKathryn M Monroe
Yoshihiro Hayakawa
Chris S Rae
Russell E Vance
Joshua J Woodward
Sky W Brubaker
Jakob von Moltke
Katia Sotelo-Troha
P2860cites workIFI16 is an innate immune sensor for intracellular DNAQ24301720
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerizationQ24310014
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activationQ24316038
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune responseQ24317784
STING is an endoplasmic reticulum adaptor that facilitates innate immune signallingQ24336398
c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon responseQ24616827
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMPQ24642631
Roles of cyclic diguanylate in the regulation of bacterial pathogenesisQ24656979
A census of membrane-bound and intracellular signal transduction proteins in bacteria: bacterial IQ, extroverts and introvertsQ24810727
Great times for small molecules: c-di-AMP, a second messenger candidate in Bacteria and ArchaeaQ46421470
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccinesQ56897738
IFN Regulatory Factor 3-Dependent Induction of Type I IFNs by Intracellular Bacteria Is Mediated by a TLR- and Nod2-Independent MechanismQ57174180
Characterization of early IL-12, IFN-alphabeta, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infectionQ71120565
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsQ27860900
Virus interference. I. The interferonQ28181608
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathwayQ28190704
Triggering the interferon antiviral response through an IKK-related pathwayQ28191761
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunityQ28509328
Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1Q28511836
Identification of Lps2 as a key transducer of MyD88-independent TIR signallingQ28587545
Type I interferons in host defenseQ29615912
Regulation of cellulose synthesis in Acetobacter xylinum by cyclic diguanylic acidQ29620651
Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogenQ33314599
Characterization of the interferon-producing cell in mice infected with Listeria monocytogenesQ33422966
Listeria pathogenesis and molecular virulence determinantsQ33975740
Innate recognition of bacteria by a macrophage cytosolic surveillance pathwayQ34161941
Characterization of Listeria monocytogenes pathogenesis in a strain expressing perfringolysin O in place of listeriolysin OQ34549065
MDA5/RIG-I and virus recognition.Q34749821
Mice lacking the type I interferon receptor are resistant to Listeria monocytogenesQ36399578
Type I interferon production enhances susceptibility to Listeria monocytogenes infectionQ36399599
Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infectionQ36402851
Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing moleculesQ36535512
Listeriolysin O: a phagosome-specific lysinQ36919588
Induction of type I interferons by bacteriaQ37756215
IFNbeta responses induced by intracellular bacteria or cytosolic DNA in different human cells do not require ZBP1 (DLM-1/DAI).Q39943290
Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirusQ44013677
Cross-priming of CD8+ T cells stimulated by virus-induced type I interferonQ44860628
CD14 is required for MyD88-independent LPS signaling.Q45990170
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectListeria monocytogenesQ292015
bites and stingsQ54911704
P304page(s)688-694
P577publication date2010-11-22
P1433published inInfection and ImmunityQ6029193
P1476titleThe N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides
P478volume79

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