review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Bernhard Ryffel | Q40398470 |
P2093 | author name string | Sergio C Oliveira | |
Sulayman Benmerzoug | |||
Fabio V Marinho | |||
V F J Quesniaux | |||
P2860 | cites work | The WHO 2014 global tuberculosis report--further to go. | Q41582280 |
Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling | Q41851410 | ||
c-di-AMP reports DNA integrity during sporulation in Bacillus subtilis | Q42783443 | ||
Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria | Q43596491 | ||
Great times for small molecules: c-di-AMP, a second messenger candidate in Bacteria and Archaea | Q46421470 | ||
Type VII secretion--mycobacteria show the way. | Q48689947 | ||
Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole | Q50083524 | ||
Corrigendum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. | Q50996942 | ||
Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs. | Q52891231 | ||
NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase | Q22010870 | ||
Mitochondrial DNA stress primes the antiviral innate immune response | Q23030015 | ||
Activation of STAT6 by STING is critical for antiviral innate immunity | Q24293312 | ||
Structurally distinct bacterial TBC-like GAPs link Arf GTPase to Rab1 inactivation to counteract host defenses | Q24297790 | ||
IFI16 is an innate immune sensor for intracellular DNA | Q24301720 | ||
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway | Q24306635 | ||
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC | Q24319706 | ||
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome | Q24319799 | ||
The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA | Q24321482 | ||
Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway | Q24601311 | ||
c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response | Q24616827 | ||
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP | Q24642631 | ||
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response | Q24643548 | ||
Roles of cyclic diguanylate in the regulation of bacterial pathogenesis | Q24656979 | ||
STING: infection, inflammation and cancer | Q26776009 | ||
STING-Dependent 2'-5' Oligoadenylate Synthetase-Like Production Is Required for Intracellular Mycobacterium leprae Survival | Q39758154 | ||
Group A streptococcus activates type I interferon production and MyD88-dependent signaling without involvement of TLR2, TLR4, and TLR9. | Q40088398 | ||
HIV Triggers a cGAS-Dependent, Vpu- and Vpr-Regulated Type I Interferon Response in CD4+ T Cells | Q40516205 | ||
Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide. | Q40548680 | ||
The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA. | Q40586213 | ||
iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING. | Q40610046 | ||
Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production | Q40613531 | ||
LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner | Q40673144 | ||
Viruses transfer the antiviral second messenger cGAMP between cells | Q41079643 | ||
Transmission of innate immune signaling by packaging of cGAMP in viral particles | Q41079648 | ||
Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis | Q41116868 | ||
Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1. | Q41181573 | ||
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida | Q41429405 | ||
Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons | Q27314790 | ||
Structural mechanism of cytosolic DNA sensing by cGAS | Q27678393 | ||
Oligoadenylate synthase-like (OASL) proteins: dual functions and associations with diseases | Q28082381 | ||
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA | Q28118718 | ||
BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses | Q28264207 | ||
Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence | Q28485721 | ||
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity | Q28509328 | ||
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response | Q28510485 | ||
TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING | Q28545831 | ||
Age-enhanced endoplasmic reticulum stress contributes to increased Atg9A inhibition of STING-mediated IFN-β production during Streptococcus pneumoniae infection | Q28590924 | ||
NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING | Q28975619 | ||
TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation | Q29030353 | ||
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages | Q29547420 | ||
Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response | Q30009223 | ||
Salmonella Suppresses the TRIF-Dependent Type I Interferon Response in Macrophages | Q30277329 | ||
Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4. | Q33592743 | ||
Stimulator of IFN gene is critical for induction of IFN-beta during Chlamydia muridarum infection | Q33824328 | ||
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity | Q33830730 | ||
Identification of a Streptococcus pyogenes SF370 gene involved in production of c-di-AMP. | Q33912627 | ||
Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection | Q33916629 | ||
MyD88 and STING signaling pathways are required for IRF3-mediated IFN-β induction in response to Brucella abortus infection | Q33988738 | ||
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. | Q34006614 | ||
c-di-AMP is a new second messenger in Staphylococcus aureus with a role in controlling cell size and envelope stress | Q34016233 | ||
cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING. | Q34084866 | ||
The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides | Q34151349 | ||
Molecular basis of group A streptococcal virulence | Q34188734 | ||
STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway | Q34259150 | ||
Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages | Q34275913 | ||
Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway | Q34324531 | ||
The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING | Q34346633 | ||
The DNA sensor, cyclic GMP-AMP synthase, is essential for induction of IFN-β during Chlamydia trachomatis infection. | Q34419467 | ||
cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection | Q34469746 | ||
Inflammasomes as polyvalent cell death platforms | Q34520989 | ||
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP | Q34550996 | ||
Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tract | Q35006270 | ||
STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors. | Q35263440 | ||
A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis. | Q35328612 | ||
The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy | Q35738682 | ||
Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis | Q35835759 | ||
Hyperinduction of host beta interferon by a Listeria monocytogenes strain naturally overexpressing the multidrug efflux pump MdrT. | Q35867588 | ||
Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses | Q35946145 | ||
STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease | Q35956285 | ||
Group A streptococci efficiently invade human respiratory epithelial cells | Q35961517 | ||
DNA-sensing inflammasomes: regulation of bacterial host defense and the gut microbiota | Q35983307 | ||
Salmonella Typhimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively | Q35988743 | ||
The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent | Q36097401 | ||
Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA. | Q36707566 | ||
The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons | Q36857386 | ||
STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection. | Q36872696 | ||
Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ | Q37044189 | ||
TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA. | Q37055696 | ||
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication. | Q37353206 | ||
The Bacterial Second Messenger Cyclic di-GMP Regulates Brucella Pathogenesis and Leads to Altered Host Immune Response | Q37424996 | ||
The ubiquitin ligase parkin mediates resistance to intracellular pathogens | Q37458253 | ||
AIM2 inhibits autophagy and IFN-β production during M. bovis infection | Q37565010 | ||
Neisseria gonorrhoeae survives within and modulates apoptosis and inflammatory cytokine production of human macrophages | Q37590165 | ||
Functional organization of mammalian mitochondrial DNA in nucleoids: history, recent developments, and future challenges. | Q37655959 | ||
Type III secretion, contact-dependent model for the intracellular development of chlamydia | Q37861994 | ||
Selective autophagy | Q38144281 | ||
STING-dependent cytosolic DNA sensing pathways | Q38169005 | ||
Microbial sensing by Toll-like receptors and intracellular nucleic acid sensors | Q38258737 | ||
STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy? | Q38293111 | ||
The cGAS-STING Defense Pathway and Its Counteraction by Viruses | Q38500828 | ||
Transcription Factor NF-κB: An Update on Intervention Strategies | Q38802627 | ||
Bacterial E3 Ubiquitin Ligase IpaH4.5 of Shigella flexneri Targets TBK1 To Dampen the Host Antibacterial Response | Q38809321 | ||
The role of autophagy in microbial infection and immunity | Q38912271 | ||
Cytosolic RNA:DNA hybrids activate the cGAS-STING axis | Q38937702 | ||
The ER-associated protein ZDHHC1 is a positive regulator of DNA virus-triggered, MITA/STING-dependent innate immune signaling | Q38949484 | ||
P921 | main subject | bites and stings | Q54911704 |
P577 | publication date | 2017-06-15 | |
P1433 | published in | Trends in Microbiology | Q15265732 |
P1476 | title | The Emerging Roles of STING in Bacterial Infections |
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