scholarly article | Q13442814 |
P819 | ADS bibcode | 2017NatCo...8..427G |
P6179 | Dimensions Publication ID | 1091449498 |
P356 | DOI | 10.1038/S41467-017-00573-W |
P932 | PMC publication ID | 5585373 |
P698 | PubMed publication ID | 28874664 |
P50 | author | Andrea Ablasser | Q15990466 |
Andreas Villunger | Q57417957 | ||
Ute Koch | Q87711326 | ||
Lionel Apetoh | Q40455935 | ||
Freddy Radtke | Q41621239 | ||
P2093 | author name string | Fabian Schuler | |
Muhammet F Gulen | |||
Simone M Haag | |||
P2860 | cites work | Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation. | Q50657210 |
Production and titration of lentiviral vectors | Q85181832 | ||
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway | Q24306635 | ||
STING is a direct innate immune sensor of cyclic di-GMP | Q24633648 | ||
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP | Q24642631 | ||
STING: infection, inflammation and cancer | Q26776009 | ||
Species-specific detection of the antiviral small-molecule compound CMA by STING | Q27677466 | ||
Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase | Q27678007 | ||
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA | Q28118718 | ||
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation | Q28256216 | ||
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity | Q28509328 | ||
cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING. | Q34084866 | ||
The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides | Q34151349 | ||
Activated STING in a vascular and pulmonary syndrome | Q34241214 | ||
The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING | Q34346633 | ||
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses | Q34362864 | ||
Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP. | Q34374085 | ||
The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells. | Q34387350 | ||
Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more | Q34987905 | ||
Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations | Q35145346 | ||
STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors. | Q35263440 | ||
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity | Q35634752 | ||
STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity | Q36394326 | ||
The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection | Q36402648 | ||
STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease. | Q37236401 | ||
Innate immune sensing and signaling of cytosolic nucleic acids | Q38198154 | ||
Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells | Q38788154 | ||
The role of cGAS in innate immunity and beyond | Q38827865 | ||
Viruses transfer the antiviral second messenger cGAMP between cells | Q41079643 | ||
Transmission of innate immune signaling by packaging of cGAMP in viral particles | Q41079648 | ||
Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1. | Q41181573 | ||
Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling | Q41851410 | ||
Host restriction factor SAMHD1 limits human T cell leukemia virus type 1 infection of monocytes via STING-mediated apoptosis | Q42261339 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 427 | |
P577 | publication date | 2017-09-05 | |
P1433 | published in | Nature Communications | Q573880 |
P1476 | title | Signalling strength determines proapoptotic functions of STING. | |
P478 | volume | 8 |
Q59350365 | A human gain-of-function STING mutation causes immunodeficiency and gammaherpesvirus-induced pulmonary fibrosis in mice |
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Q93013037 | Diminished stimulator of interferon genes production with cigarette smoke-exposure contributes to weakened anti-adenovirus vectors response and destruction of lung in chronic obstructive pulmonary disease model |
Q58759112 | Enhancing immunotherapy of STING agonist for lymphoma in preclinical models |
Q58553780 | From Colitis to Cancer: An Evolutionary Trajectory That Merges Maths and Biology |
Q92093680 | HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity |
Q92828439 | Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models |
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Q97553625 | Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids |
Q90246592 | Inflammatory microenvironment remodelling by tumour cells after radiotherapy |
Q59357016 | Interaction of Viral Capsid-Derived Virus-Like Particles (VLPs) with the Innate Immune System |
Q91907950 | Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signalling |
Q90275102 | Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation |
Q58762068 | Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage |
Q99616121 | Notch signaling protects CD4 T cells from STING-mediated apoptosis during acute systemic inflammation |
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Q90288795 | Pharmacological modulation of nucleic acid sensors - therapeutic potential and persisting obstacles |
Q90315050 | Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma |
Q61443764 | Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function |
Q91826761 | Regulation of cGAS- and RLR-mediated immunity to nucleic acids |
Q94921871 | Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response |
Q59350771 | Role of the cGAS-STING pathway in cancer development and oncotherapeutic approaches |
Q97636476 | STEEP mediates STING ER exit and activation of signaling |
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Q92664085 | STING modulators: Predictive significance in drug discovery |
Q104795145 | STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway |
Q92642973 | STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment |
Q92459396 | STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death |
Q55412846 | Stimulator of Interferon Genes in Classical Dendritic Cells Controls Mucosal Th17 Responses to Cyclic Dinucleotides for Host Defenses Against Microbial Infections in Gut. |
Q64067840 | Supramolecular Complexes in Cell Death and Inflammation and Their Regulation by Autophagy |
Q90110242 | TMEM173 Drives Lethal Coagulation in Sepsis |
Q54220697 | TMEM173 variants and potential importance to human biology and disease. |
Q52568331 | Targeting Cytosolic Nucleic Acid-Sensing Pathways for Cancer Immunotherapies. |
Q92424052 | Targeting the STING pathway in tumor-associated macrophages regulates innate immune sensing of gastric cancer cells |
Q92093282 | The Cytosolic DNA-Sensing cGAS-STING Pathway in Cancer |
Q57180728 | The allosteric activation of cGAS underpins its dynamic signaling landscape |
Q91329987 | The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma |
Q88286449 | The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer |
Q90415361 | The mitochondria in lung fibrosis: friend or foe? |
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