Signalling strength determines proapoptotic functions of STING.

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Signalling strength determines proapoptotic functions of STING. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2017NatCo...8..427G
P6179Dimensions Publication ID1091449498
P356DOI10.1038/S41467-017-00573-W
P932PMC publication ID5585373
P698PubMed publication ID28874664

P50authorAndrea AblasserQ15990466
Andreas VillungerQ57417957
Ute KochQ87711326
Lionel ApetohQ40455935
Freddy RadtkeQ41621239
P2093author name stringFabian Schuler
Muhammet F Gulen
Simone M Haag
P2860cites workHes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation.Q50657210
Production and titration of lentiviral vectorsQ85181832
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathwayQ24306635
STING is a direct innate immune sensor of cyclic di-GMPQ24633648
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMPQ24642631
STING: infection, inflammation and cancerQ26776009
Species-specific detection of the antiviral small-molecule compound CMA by STINGQ27677466
Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP SynthaseQ27678007
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNAQ28118718
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activationQ28256216
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunityQ28509328
cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.Q34084866
The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotidesQ34151349
Activated STING in a vascular and pulmonary syndromeQ34241214
The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STINGQ34346633
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retrovirusesQ34362864
Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.Q34374085
The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells.Q34387350
Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and moreQ34987905
Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestationsQ35145346
STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.Q35263440
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and ImmunityQ35634752
STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunityQ36394326
The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infectionQ36402648
STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.Q37236401
Innate immune sensing and signaling of cytosolic nucleic acidsQ38198154
Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B CellsQ38788154
The role of cGAS in innate immunity and beyondQ38827865
Viruses transfer the antiviral second messenger cGAMP between cellsQ41079643
Transmission of innate immune signaling by packaging of cGAMP in viral particlesQ41079648
Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1.Q41181573
Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signalingQ41851410
Host restriction factor SAMHD1 limits human T cell leukemia virus type 1 infection of monocytes via STING-mediated apoptosisQ42261339
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)427
P577publication date2017-09-05
P1433published inNature CommunicationsQ573880
P1476titleSignalling strength determines proapoptotic functions of STING.
P478volume8

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cites work (P2860)
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