B cell MHC Class II Signaling: a Story of Life and Death.

scientific article published on 28 April 2018

B cell MHC Class II Signaling: a Story of Life and Death. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.HUMIMM.2018.04.013
P932PMC publication ID6207480
P698PubMed publication ID29715484

P2093author name stringLei Jin
Divya Sai Katikaneni
P2860cites workSTING is an endoplasmic reticulum adaptor that facilitates innate immune signallingQ24336398
SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signalingQ24338194
MHC class II association with lipid rafts on the antigen presenting cell surfaceQ27008954
Association of four antigens of the tetraspans family (CD37, CD53, TAPA-1, and R2/C33) with MHC class II glycoproteinsQ28250176
Phase II study on the addition of ASA404 (vadimezan; 5,6-dimethylxanthenone-4-acetic acid) to docetaxel in CRMPCQ28282150
The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO moleculesQ28284349
Supramolecular complexes of MHC class I, MHC class II, CD20, and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JYQ28290621
Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and futureQ28292558
B cell follicles and antigen encounters of the third kindQ28296142
The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formationQ28586300
Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding PocketQ30395581
Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cellsQ30489241
Fully human, HLA-DR-specific monoclonal antibodies efficiently induce programmed death of malignant lymphoid cellsQ31095104
TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers.Q32062094
1D09C3, an mAb specific for MHC-II.Q33316942
B cell development: signal transduction by antigen receptors and their surrogates.Q33632426
Therapy of B-cell malignancies by anti-HLA-DR humanized monoclonal antibody, IMMU-114, is mediated through hyperactivation of ERK and JNK MAP kinase signaling pathwaysQ33944243
Early events in B cell activationQ34101385
Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responsesQ34110588
Activated STING in a vascular and pulmonary syndromeQ34241214
Distinct MHC Class II Molecules Are Associated on the Dendritic Cell Surface in Cholesterol-dependent Membrane MicrodomainsQ34284990
The membrane skeleton controls diffusion dynamics and signaling through the B cell receptorQ34322410
Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acidQ34339243
Identification and characterization of a loss-of-function human MPYS variantQ35022308
A novel, alternative pathway of apoptosis triggered through class II major histocompatibility complex moleculesQ35556831
MHC class II signaling in antigen-presenting cellsQ35634046
STING Negatively Regulates Double-Stranded DNA-Activated JAK1-STAT1 Signaling via SHP-1/2 in B CellsQ35644477
TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation.Q35739705
B cell antigen receptor signaling 101.Q35818846
In Vivo Pharmacodynamic Effects of Hu1D10 (Remitogen), a Humanized Antibody Reactive Against a Polymorphic Determinant of HLA-DR Expressed on B CellsQ57373163
Phase II Trial of Remitogen™ (Humanized 1D10) Monoclonal Antibody Targeting Class II in Patients with Relapsed Low-Grade or Follicular LymphomaQ57376036
CD40 ligand-transduced co-stimulation of T cells in the development of helper functionQ58882277
Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytesQ59073132
The Actin and Tetraspanin Networks Organize Receptor Nanoclusters to Regulate B Cell Receptor-Mediated SignalingQ63409208
Selective in vivo antitumor effects of monoclonal anti-I-A antibody on B cell lymphomaQ68834769
Engagement of MHC class II molecules by staphylococcal superantigens activates src-type protein tyrosine kinasesQ71613579
A caspase-independent pathway of MHC class II antigen-mediated apoptosis of human B lymphocytesQ73050432
HLA class II-mediated death is induced via Fas/Fas ligand interactions in human splenic B lymphocytesQ73128519
Regulation of MHC class II signal transduction by the B cell coreceptors CD19 and CD22Q73163129
CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation.Q35962812
B Cell-Specific MHC Class II Deletion Reveals Multiple Nonredundant Roles for B Cell Antigen Presentation in Murine Lupus.Q36031630
MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain lengthQ36061581
MHC class II structural requirements for the association with Igalpha/beta, and signaling of calcium mobilization and cell deathQ36713712
Major histocompatibility complex (MHC) class II-peptide complexes arrive at the plasma membrane in cholesterol-rich microclustersQ36832560
MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signalsQ36845998
Pivotal advance: eosinophils mediate early alum adjuvant-elicited B cell priming and IgM productionQ37327241
MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodiesQ37397820
Visualizing the molecular and cellular events underlying the initiation of B-cell activationQ37517325
SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophagesQ37598447
NF-κB: roles and regulation in different CD4(+) T-cell subsetsQ38081166
Tetraspanins at a glance.Q38240344
Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B CellsQ38788154
The tetraspanin web revisited by super-resolution microscopyQ38852168
The tyrosine kinase Src promotes phosphorylation of the kinase TBK1 to facilitate type I interferon production after viral infection.Q39042145
The Common R71H-G230A-R293Q Human TMEM173 Is a Null AlleleQ39121627
Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA.Q39235226
Dynamics within tetraspanin pairs affect MHC class II expressionQ39402003
The in vitro biological activity of the HLA-DR-binding clinical IgG4 antibody 1D09C3 is a consequence of the disruption of cell aggregates and can be abrogated by Fab arm exchangeQ39809598
Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivoQ39822717
MHC class II molecules activate NFAT and the ERK group of MAPK through distinct signaling pathways in B cellsQ39835067
Phase II study of ASA404 (vadimezan, 5,6-dimethylxanthenone-4-acetic acid/DMXAA) 1800mg/m(2) combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancerQ39983076
The anti-human leukocyte antigen-DR monoclonal antibody 1D09C3 activates the mitochondrial cell death pathway and exerts a potent antitumor activity in lymphoma-bearing nonobese diabetic/severe combined immunodeficient miceQ40321930
A phase I/II dose escalation study of apolizumab (Hu1D10) using a stepped-up dosing schedule in patients with chronic lymphocytic leukemia and acute leukemiaQ40375510
Signaling through HLA-DR induces PKC beta-dependent B cell death outside raftsQ40659031
Lipid raft-dependent and -independent signaling through HLA-DR moleculesQ40681344
CD20 is physically and functionally coupled to MHC class II and CD40 on human B cell linesQ40975312
Signalling strength determines proapoptotic functions of STING.Q41621190
Human B cells fail to secrete type I interferons upon cytoplasmic DNA exposureQ41926622
Major histocompatibility class II-mediated signal transduction is regulated by the protein-tyrosine phosphatase CD45.Q42454385
Early biochemical events after MHC class II-mediated signaling on human B lymphocytesQ42637623
MHC class II-mediated apoptosis of mature dendritic cells proceeds by activation of the protein kinase C-delta isoenzymeQ44082619
MHC class II signaling function is regulated during maturation of plasmacytoid dendritic cellsQ44224972
Th2-dependent B cell responses in the absence of CD40-CD40 ligand interactionsQ44648165
Clinical safety and pharmacological profile of the HLA-DR antibody 1D09C3 in patients with B cell chronic lymphocytic leukemia and lymphoma: results from a phase I studyQ44797709
Randomized phase III placebo-controlled trial of carboplatin and paclitaxel with or without the vascular disrupting agent vadimezan (ASA404) in advanced non-small-cell lung cancerQ44915586
Modeling of T cell contact-dependent B cell activation. IL-4 and antigen receptor ligation primes quiescent B cells to mobilize calcium in response to Ia cross-linkingQ44928750
Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytesQ44944046
MHC class II/CD38/CD9: a lipid-raft-dependent signaling complex in human monocytesQ46533260
Promotion of B cell immune responses via an alum-induced myeloid cell populationQ47323242
Reference values for B cell subpopulations from infancy to adulthoodQ51036853
Role of MHC class II on memory B cells in post-germinal center B cell homeostasis and memory response.Q51985051
Clinical development of vascular disrupting agents: what lessons can we learn from ASA404?Q52613053
The CD19/CD81 complex physically interacts with CD38 but is not required to induce proliferation in mouse B lymphocytesQ57058779
P433issue1
P304page(s)37-43
P577publication date2018-04-28
P1433published inHuman ImmunologyQ15709955
P1476titleB cell MHC class II signaling: A story of life and death
P478volume80

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cites work (P2860)
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