The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast (scientific article)

Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q24537200

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

Q27860477

Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19.

Q27932730

Characterization of the BUD31 gene of Saccharomyces cerevisiae

Q27933708

Involvement of the spliceosomal U4 small nuclear RNA in heterochromatic gene silencing at fission yeast centromeres

Q42918010

Repeat-induced gene silencing in mammals.

Q44031048

RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins

Q44952131

Regulation of Swi6/HP1-dependent heterochromatin assembly by cooperation of components of the mitogen-activated protein kinase pathway and a histone deacetylase Clr6.

Q45005910

Context dependent splicing functions of Bud31/Ycr063w define its role in budding and cell cycle progression

Q45328682

Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila

Q52542203

Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.

Q55039785

Synthetic Genetic Array (SGA) Analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe

Q56994328

Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast

Q57973165

A transcription factor–based mechanism for mouse heterochromatin formation

Q64387285

Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function

Q71821145

Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres

Q81389440

The spliceosome: design principles of a dynamic RNP machine

Q28131809

Functional genomic analysis of RNA interference in C. elegans

Q28241721

Small RNAs in transcriptional gene silencing and genome defence

Q28307317

Heterochromatin revisited

Q29614716

Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly

Q29614718

Fission yeast Tel1(ATM) and Rad3(ATR) promote telomere protection and telomerase recruitment

Q33497909

Histone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeast

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Splicing factor Spf30 assists exosome-mediated gene silencing in fission yeast

Q33648862

Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex

Q33770574

Requirement of heterochromatin for cohesion at centromeres

Q34094956

Recruitment of cohesin to heterochromatic regions by Swi6/HP1 in fission yeast

Q34108294

cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site

Q34152857

Common ground: small RNA programming and chromatin modifications

Q34176993

Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation.

Q34318276

Telomere-associated chromosome breakage in fission yeast results in variegated expression of adjacent genes

Q34332700

RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond

Q34385616

Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres.

Q34452191

Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe

Q34466609

Elimination of a specific histone H3K14 acetyltransferase complex bypasses the RNAi pathway to regulate pericentric heterochromatin functions

Q34557115

Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution

Q34779368

Splicing factors facilitate RNAi-directed silencing in fission yeast

Q34864584

Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres.

Q34989114

Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis

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The splicing factor SR45 affects the RNA-directed DNA methylation pathway in Arabidopsis

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Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein

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Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast.

Q37365634

Heterochromatin maintenance and establishment: lessons from the mouse pericentromere

Q37937379

Functional separation of the requirements for establishment and maintenance of centromeric heterochromatin.

Q38301349

Comparative analysis of argonaute-dependent small RNA pathways in Drosophila

Q39913357

A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast.

Q40197642

Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10.

Q41790611

Heterochromatin links to centromeric protection by recruiting shugoshin

Q42152372

A novel RNAi protein, Dsh1, assembles RNAi machinery on chromatin to amplify heterochromatic siRNA.

Q42321072

Ers1, a rapidly diverging protein essential for RNA interference-dependent heterochromatic silencing in Schizosaccharomyces pombe

Q42458688

Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence

Q42584215

P275

Creative Commons Attribution 4.0 International

copyrighted

issue

page(s)

e1004334

P577

publication date

2014-05-29

P1433

published in

PLOS Genetics

Q1893441

P1476

title

The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast

P478

volume

Reverse relations

cites work (P2860)

Q34441358	A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast
Q92811766	Centromeric Non-Coding RNAs: Conservation and Diversity in Function
Q36958121	Interconnections Between RNA-Processing Pathways Revealed by a Sequencing-Based Genetic Screen for Pre-mRNA Splicing Mutants in Fission Yeast
Q35223649	RNA-mediated epigenetic regulation of gene expression
Q47633384	Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing
Q37189009	Set3 contributes to heterochromatin integrity by promoting transcription of subunits of Clr4-Rik1-Cul4 histone methyltransferase complex in fission yeast
Q36409104	Splicing stimulates siRNA formation at Drosophila DNA double-strand breaks.
Q41729977	The Conserved RNA Binding Cyclophilin, Rct1, Regulates Small RNA Biogenesis and Splicing Independent of Heterochromatin Assembly
Q38935467	The RNA-binding protein HOS5 and serine/arginine-rich proteins RS40 and RS41 participate in miRNA biogenesis in Arabidopsis
Q87203026	The effect of the cwf14 gene of fission yeast on cell wall integrity is associated with rho1
Q26780444	The expanding world of small RNAs in plants
Q36288451	The intron in centromeric noncoding RNA facilitates RNAi-mediated formation of heterochromatin.
Q35961743	The proper connection between shelterin components is required for telomeric heterochromatin assembly.
Q34313064	Tls1 regulates splicing of shelterin components to control telomeric heterochromatin assembly and telomere length.