Paradoxical effects of all-trans-retinoic acid on lupus-like disease in the MRL/lpr mouse model

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Paradoxical effects of all-trans-retinoic acid on lupus-like disease in the MRL/lpr mouse model is …
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scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1018176L
P356DOI10.1371/JOURNAL.PONE.0118176
P932PMC publication ID4361690
P698PubMed publication ID25775135
P5875ResearchGate publication ID273694453

P50authorXin M LuoQ56992804
P2093author name stringA Catharine Ross
Jingjing Ren
Bernard S Jortner
Cheng-Hsin Wei
S Ansar Ahmed
Thomas E Cecere
Xiaofeng Liao
P2860cites workAll trans retinoic acid in acute promyelocytic leukemiaQ27824776
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Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acidQ29615586
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Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acidQ29619479
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A retinoic acid-dependent network in the foregut controls formation of the mouse lung primordiumQ33882861
Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosusQ33920964
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Vitamin A and immune function: retinoic acid modulates population dynamics in antigen receptor and CD38-stimulated splenic B cellsQ34063549
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All-trans-retinoic acid inhibits the development of mesangial proliferative glomerulonephritis in interleukin-6 transgenic mice.Q54673446
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Genomic view of systemic autoimmunity in MRLlpr miceQ82689901
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Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptorsQ44526952
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CCR6 regulates EAE pathogenesis by controlling regulatory CD4+ T-cell recruitment to target tissuesQ48585453
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Apoptotic-cell-derived membrane vesicles induce an alternative maturation of human dendritic cells which is disturbed in SLE.Q53141965
Systemic lupus erythematosus.Q53202066
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Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damageQ34443260
Murine models of systemic lupus erythematosusQ34591019
Retinoic acid metabolism and mechanism of action: a reviewQ35061108
Retinoic acid and α-galactosylceramide differentially regulate B cell activation in vitro and augment antibody production in vivoQ35066481
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B cell proliferation, somatic hypermutation, class switch recombination, and autoantibody production in ectopic lymphoid tissue in murine lupusQ36091161
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The role of retinoic acid in tolerance and immunityQ36162881
GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cellsQ36398839
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathwayQ36407194
Retinoic acid promotes mouse splenic B cell surface IgG expression and maturation stimulated by CD40 and IL-4.Q36487660
Taming lupus-a new understanding of pathogenesis is leading to clinical advancesQ36712941
Regulation of basement membrane-reactive B cells in BXSB, (NZBxNZW)F1, NZB, and MRL/lpr lupus miceQ36763279
Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice.Q36811047
Retinoic acid controls the homeostasis of pre-cDC-derived splenic and intestinal dendritic cellsQ37194931
Exclusive CX3CR1 dependence of kidney DCs impacts glomerulonephritis progressionQ37200899
Cutting edge: Regulatory T cells directly suppress B cells in systemic lupus erythematosusQ37314612
Retinoic acid combined with vitamin A synergizes to increase retinyl ester storage in the lungs of newborn and dexamethasone-treated neonatal ratsQ37349086
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Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritisQ37419201
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Autoantibodies and resident renal cells in the pathogenesis of lupus nephritis: getting to know the unknown.Q38023852
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Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cellsQ38623614
Retinoic acid induces homing of protective T and B cells to the gut after subcutaneous immunization in miceQ39043532
Vitamin A and retinoic acid act synergistically to increase lung retinyl esters during normoxia and reduce hyperoxic lung injury in newborn miceQ41171769
The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cellsQ41687602
Retinoic acid therapy attenuates the severity of tuberculosis while altering lymphocyte and macrophage numbers and cytokine expression in rats infected with Mycobacterium tuberculosisQ41775129
Retinoic acid treatment protects MRL/lpr lupus mice from the development of glomerular diseaseQ42466551
All-Trans-Retinoic Acid Pharmacology and Its Impact on the Treatment of Acute Promyelocytic LeukemiaQ42604769
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjecttretinoinQ29417
P304page(s)e0118176
P577publication date2015-03-16
P1433published inPLOS OneQ564954
P1476titleParadoxical effects of all-trans-retinoic acid on lupus-like disease in the MRL/lpr mouse model
P478volume10

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cites work (P2860)
Q38406678All- Trans-Retinoic Acid Augments the Histopathological Outcome of Neuroinflammation and Neurodegeneration in Lupus-Prone MRL/lpr Mice
Q39178961An update on diet and nutritional factors in systemic lupus erythematosus management.
Q42653229Antibiotics ameliorate lupus-like symptoms in mice.
Q26748941Breakdown of Immune Tolerance in Systemic Lupus Erythematosus by Dendritic Cells
Q33893588Control of lupus nephritis by changes of gut microbiota.
Q45020306Cutting Edge: Plasmacytoid Dendritic Cells in Late-Stage Lupus Mice Defective in Producing IFN-α.
Q45074538Gut microbiota in human SLE and a mouse model of lupus
Q38865890How the microbiota shapes rheumatic diseases
Q98465680Immunomodulatory Effects of Diet and Nutrients in Systemic Lupus Erythematosus (SLE): A Systematic Review
Q33859906Pin1-Targeted Therapy for Systemic Lupus Erythematosus
Q45063635Renal-infiltrating CD11c+ cells are pathogenic in murine lupus nephritis through promoting CD4+ T cell responses.
Q91711860Retinoic Acid Exerts Disease Stage-Dependent Effects on Pristane-Induced Lupus
Q58801064Retinoic Acid, Leaky Gut, and Autoimmune Diseases
Q26773130SLE: Another Autoimmune Disorder Influenced by Microbes and Diet?
Q45066620Selective HDAC6 inhibition decreases early stage of lupus nephritis by down-regulating both innate and adaptive immune responses.
Q38830159The safety of isotretinoin in patients with lupus nephritis: a comprehensive review
Q47600588Transcription factor ISX mediates the cross talk between diet and immunity

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