Thermodynamics of the DNA damage repair steps of human 8-oxoguanine DNA glycosylase.

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Thermodynamics of the DNA damage repair steps of human 8-oxoguanine DNA glycosylase. is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...998495K
P356DOI10.1371/JOURNAL.PONE.0098495
P932PMC publication ID4049573
P698PubMed publication ID24911585
P5875ResearchGate publication ID262940208

P50authorNikita A. KuznetsovQ54327373
Olga S. FedorovaQ54327407
P2093author name stringLev N Krasnoperov
Yuri N Vorobjev
Alexandra A Kuznetsova
P2860cites workCloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiaeQ24317398
Kinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylaseQ24812802
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNAQ27621681
Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylaseQ27638390
Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylaseQ27640474
Conformational dynamics of the interaction of Escherichia coli endonuclease VIII with DNA substrates.Q54327315
Hydroxyl radical generation and DNA strand scission mediated by natural anticancer and synthetic quinonesQ57018351
Structural and thermodynamic strategies for site-specific DNA binding proteinsQ73195463
Kinetic conformational analysis of human 8-oxoguanine-DNA glycosylaseQ79337058
Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutationsQ79370035
Influence of base stacking and hydrogen bonding on the fluorescence of 2-aminopurine and pyrrolocytosine in nucleic acidsQ79982045
Product-assisted catalysis in base-excision DNA repairQ27640521
Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structureQ27729885
Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinaseQ29617738
Step-by-step mechanism of DNA damage recognition by human 8-oxoguanine DNA glycosylase.Q30354174
SIMS: computation of a smooth invariant molecular surfaceQ33907169
Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sitesQ34250273
Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.Q34407601
Biological consequences of free radical-damaged DNA bases.Q34710048
Interpreting protein/DNA interactions: distinguishing specific from non-specific and electrostatic from non-electrostatic componentsQ34779522
Mutagenicity, toxicity and repair of DNA base damage induced by oxidationQ35592850
Oxidative DNA damage and disease: induction, repair and significanceQ35876708
Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1.Q36127010
Real-time studies of conformational dynamics of the repair enzyme E. coli formamidopyrimidine-DNA glycosylase and its DNA complexes during catalytic cycleQ37596621
Advances in implicit models of water solvent to compute conformational free energy and molecular dynamics of proteins at constant pH.Q37932679
Substrate specificity and reaction mechanism of murine 8-oxoguanine-DNA glycosylaseQ38310719
Hydrogen bonding, hydrophobicity, packing, and protein foldingQ40832983
Thermodynamics of the multi-stage DNA lesion recognition and repair by formamidopyrimidine-DNA glycosylase using pyrrolocytosine fluorescence--stopped-flow pre-steady-state kineticsQ42157248
Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamilyQ42638192
Reversible chemical step and rate-limiting enzyme regeneration in the reaction catalyzed by formamidopyrimidine-DNA glycosylase.Q43260157
Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase betaQ44130577
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutionsQ44480509
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectthermodynamicsQ11473
DNA damageQ5205747
P304page(s)e98495
P577publication date2014-06-09
P1433published inPLOS OneQ564954
P1476titleThermodynamics of the DNA damage repair steps of human 8-oxoguanine DNA glycosylase
P478volume9