Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1.

scientific article

Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.316497
P932PMC publication ID3408145
P698PubMed publication ID22511791
P5875ResearchGate publication ID224285092

P50authorMartin KarplusQ903471
Peter S KutchukianQ50731602
P2093author name stringGregory L Verdine
Charisse M Crenshaw
Kwangho Nam
Brian R Bowman
Kimberly Oo
P2860cites workCrystal structure of the nucleosome core particle at 2.8 A resolutionQ22122355
Instability and decay of the primary structure of DNAQ22122361
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNAQ24324515
PHENIX: a comprehensive Python-based system for macromolecular structure solutionQ24654617
CHARMM: the biomolecular simulation programQ24658108
Comparison of simple potential functions for simulating liquid waterQ26778447
Processing of X-ray diffraction data collected in oscillation modeQ26778468
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNAQ27621681
Structure of BamHI bound to nonspecific DNA: a model for DNA slidingQ27625226
Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylaseQ27640474
Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylaseQ27643123
BstYI bound to noncognate DNA reveals a "hemispecific" complex: implications for DNA scanningQ27644466
Enzymatic capture of an extrahelical thymine in the search for uracil in DNAQ27647377
Identification of a DNA primase template tracking site redefines the geometry of primer synthesisQ27649534
Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognitionQ27650995
Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNAQ27651423
Entrapment and Structure of an Extrahelical Guanine Attempting to Enter the Active Site of a Bacterial DNA Glycosylase, MutMQ27658059
Encounter and extrusion of an intrahelical lesion by a DNA repair enzymeQ27658654
Structure of Escherichia coli AlkA in Complex with Undamaged DNAQ27664515
X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanineQ27730354
Crystal structure of a DNA duplex containing 8-hydroxydeoxyguanine-adenine base pairsQ27730872
The crystal structure of EcoRV endonuclease and of its complexes with cognate and non-cognate DNA fragmentsQ27732162
The hyperthermophile chromosomal protein Sac7d sharply kinks DNAQ27748966
Architecture of nonspecific protein-DNA interactions in the Sso7d-DNA complexQ27764578
The crystal structure of the hyperthermophile chromosomal protein Sso7d bound to DNAQ27765277
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistanceQ27766086
All-atom empirical potential for molecular modeling and dynamics studies of proteinsQ27860468
Coot: model-building tools for molecular graphicsQ27860505
3DNA: a software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structuresQ27860547
Version 1.2 of the Crystallography and NMR systemQ27860583
Structure validation by Calpha geometry: phi,psi and Cbeta deviationQ27860657
The CCP4 suite: programs for protein crystallographyQ27861090
3-methyladenine DNA glycosylases: structure, function, and biological importanceQ28141634
Complexities of the DNA base excision repair pathway for repair of oxidative DNA damageQ28597101
Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanesQ29397708
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodGQ29616532
The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)Q29619959
FASTDXL: a generalized screen to trap disulfide-stabilized complexes for use in structural studiesQ33291097
Release of normal bases from intact DNA by a native DNA repair enzymeQ33888049
Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.Q34407601
A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex.Q35108052
Hidden in plain sight: subtle effects of the 8-oxoguanine lesion on the structure, dynamics, and thermodynamics of a 15-base pair oligodeoxynucleotide duplexQ35282603
Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cellsQ35846749
NMR studies of a DNA containing 8-hydroxydeoxyguanosineQ35918819
Genetic effects of oxidative DNA damage: comparative mutagenesis of 7,8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine in Escherichia coliQ35935140
Structure of a DNA glycosylase searching for lesionsQ38315509
Transition from nonspecific to specific DNA interactions along the substrate-recognition pathway of dam methyltransferase.Q38326532
Association of mitochondrial DNA transversion mutations with familial medullary thyroid carcinoma/multiple endocrine neoplasia type 2 syndromeQ40365390
Crystal structure of an engineered Cro monomer bound nonspecifically to DNA: possible implications for nonspecific binding by the wild-type proteinQ41854188
Poly[[tris-(μ(3)-2-oxidopyridinium-3-carboxyl-ato)manganese(II)sodium(I)] monohydrate].Q42288966
Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamilyQ42638192
A repair system for 8-oxo-7,8-dihydrodeoxyguanineQ43687308
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutionsQ44480509
Improved treatment of the protein backbone in empirical force fields.Q44735024
The structure of the human AGT protein bound to DNA and its implications for damage detectionQ45345095
Influence of the oxidatively damaged adduct 8-oxodeoxyguanosine on the conformation, energetics, and thermodynamic stability of a DNA duplex.Q52321043
Effect of 2'-deoxyguanosine oxidation at C8 position on N-glycosidic bond stability.Q53458484
Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.Q54502915
Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systemsQ56750591
Improved Fourier coefficients for maps using phases from partial structures with errorsQ56877556
Molecular dynamics with coupling to an external bathQ57569060
The critical active-site amine of the human 8-oxoguanine DNA glycosylase, hOgg1: direct identification, ablation and chemical reconstitutionQ73790587
Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutationsQ79370035
P4510describes a project that usesPyMOLQ1373457
ImageQuantQ112270642
P433issue30
P407language of work or nameEnglishQ1860
P304page(s)24916-24928
P577publication date2012-04-16
P1433published inJournal of Biological ChemistryQ867727
P1476titleEnforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1.
P478volume287

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cites work (P2860)
Q360968868-oxoguanine DNA glycosylases: one lesion, three subfamilies
Q36532622A dynamic checkpoint in oxidative lesion discrimination by formamidopyrimidine-DNA glycosylase
Q64390396A sequence-specific DNA glycosylase mediates restriction-modification in Pyrococcus abyssi
Q36049933CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage.
Q38299797Conformational Dynamics of DNA Repair by Escherichia coli Endonuclease III
Q90609846Construction of a self-directed replication system for label-free and real-time sensing of repair glycosylases with zero background
Q48340163DNA Deformation-Coupled Recognition of 8-Oxoguanine: Conformational Kinetic Gating in Human DNA Glycosylase
Q37213864DNA damage processing by human 8-oxoguanine-DNA glycosylase mutants with the occluded active site.
Q58087149Facilitated Diffusion Mechanisms in DNA Base Excision Repair and Transcriptional Activation
Q50512812Global DNA dynamics of 8-oxoguanine repair by human OGG1 revealed by stopped-flow kinetics and molecular dynamics simulation.
Q52337039Kinetics and Thermodynamics of DNA Processing by Wild Type DNA-Glycosylase Endo III and Its Catalytically Inactive Mutant Forms.
Q34306735Recent advances in the structural mechanisms of DNA glycosylases
Q39200289Repair of oxidatively induced DNA damage by DNA glycosylases: Mechanisms of action, substrate specificities and excision kinetics
Q38263205Structural Features of the Interaction between Human 8-Oxoguanine DNA Glycosylase hOGG1 and DNA.
Q27681624Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
Q89994274Targeting Base Excision Repair Glycosylases with DNA Containing Transition State Mimics Prepared via Click Chemistry
Q40072021The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts.
Q33701467The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine
Q99207485The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase
Q35184050Thermodynamics of the DNA damage repair steps of human 8-oxoguanine DNA glycosylase.