scholarly article | Q13442814 |
P50 | author | James T Stivers | Q88361476 |
P2093 | author name string | Alexandre Esadze | |
P2860 | cites work | hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup | Q24303661 |
Post-replicative base excision repair in replication foci | Q24534209 | ||
How do site-specific DNA-binding proteins find their targets? | Q24563835 | ||
HMDB 3.0--The Human Metabolome Database in 2013 | Q24595162 | ||
Nuclear and mitochondrial forms of human uracil-DNA glycosylase are encoded by the same gene | Q24633708 | ||
Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences | Q24644640 | ||
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG | Q24669704 | ||
DNA glycosylases: in DNA repair and beyond | Q26830166 | ||
What macromolecular crowding can do to a protein | Q27012942 | ||
Single-molecule visualization of RecQ helicase reveals DNA melting, nucleation, and assembly are required for processive DNA unwinding | Q27318290 | ||
Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited | Q27617728 | ||
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA | Q27621681 | ||
Structure of hybrid backbone methylphosphonate DNA heteroduplexes: effect of R and S stereochemistry | Q27637290 | ||
Product-assisted catalysis in base-excision DNA repair | Q27640521 | ||
Electrostatic guidance of glycosyl cation migration along the reaction coordinate of uracil DNA glycosylase | Q27642424 | ||
Enzymatic capture of an extrahelical thymine in the search for uracil in DNA | Q27647377 | ||
Structural Basis for the Inhibition of Human Alkyladenine DNA Glycosylase (AAG) by 3,N4-Ethenocytosine-containing DNA | Q27667051 | ||
Searching for DNA Lesions: Structural Evidence for Lower- and Higher-Affinity DNA Binding Conformations of Human Alkyladenine DNA Glycosylase | Q27676011 | ||
Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues | Q27727975 | ||
Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions | Q27733960 | ||
Cell cycle checkpoint in cancer: a therapeutically targetable double-edged sword | Q28078268 | ||
Base Excision Repair, a Pathway Regulated by Posttranslational Modifications | Q28078441 | ||
3-methyladenine DNA glycosylases: structure, function, and biological importance | Q28141634 | ||
The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media | Q28209077 | ||
DNA translocation by human uracil DNA glycosylase: role of DNA phosphate charge | Q36774056 | ||
DNA translocation by human uracil DNA glycosylase: the case of single-stranded DNA and clustered uracils | Q36790722 | ||
Uracil DNA glycosylase uses DNA hopping and short-range sliding to trap extrahelical uracils | Q36825207 | ||
Global jumping and domain-specific intersegment transfer between DNA cognate sites of the multidomain transcription factor Oct-1. | Q36893573 | ||
Extrahelical damaged base recognition by DNA glycosylase enzymes | Q37000640 | ||
Isolating contributions from intersegmental transfer to DNA searching by alkyladenine DNA glycosylase. | Q37112676 | ||
Base excision repair | Q28288115 | ||
Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins | Q28291920 | ||
Control of cell cycle transcription during G1 and S phases | Q28295030 | ||
Human alkyladenine DNA glycosylase employs a processive search for DNA damage | Q28296242 | ||
A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A | Q28304314 | ||
JASPAR: an open-access database for eukaryotic transcription factor binding profiles | Q29614419 | ||
Base-excision repair of oxidative DNA damage | Q29615373 | ||
A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA. | Q30477242 | ||
Nontarget DNA binding shapes the dynamic landscape for enzymatic recognition of DNA damage | Q30488332 | ||
Visualizing helicases unwinding DNA at the single molecule level | Q30495681 | ||
Crowding and hydrodynamic interactions likely dominate in vivo macromolecular motion | Q30497258 | ||
A benchmark for chromatin binding measurements in live cells. | Q30524321 | ||
Visualizing protein movement on DNA at the single-molecule level using DNA curtains | Q30585002 | ||
Probing the target search of DNA-binding proteins in mammalian cells using TetR as model searcher | Q30658188 | ||
Structural basis of human PCNA sliding on DNA. | Q30834894 | ||
Kinetic mechanism of damage site recognition and uracil flipping by Escherichia coli uracil DNA glycosylase | Q31931744 | ||
Rates of base excision repair are not solely dependent on levels of initiating enzymes | Q32128607 | ||
Microscopic viscosity and rotational diffusion of proteins in a macromolecular environment | Q33178223 | ||
Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA. | Q33310273 | ||
Computational models for large-scale simulations of facilitated diffusion | Q33556999 | ||
Specific cellular water dynamics observed in vivo by neutron scattering and NMR. | Q33660348 | ||
Positive and negative impacts of nonspecific sites during target location by a sequence-specific DNA-binding protein: origin of the optimal search at physiological ionic strength. | Q33791313 | ||
Hopping enables a DNA repair glycosylase to search both strands and bypass a bound protein. | Q33819477 | ||
Single-molecule analysis of steroid receptor and cofactor action in living cells. | Q33827904 | ||
Ultrafast redistribution of E. coli SSB along long single-stranded DNA via intersegment transfer | Q33895798 | ||
Nonspecifically bound proteins spin while diffusing along DNA. | Q33929106 | ||
Sp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancer | Q33952921 | ||
Base excision repair of DNA in mammalian cells | Q33957142 | ||
Microscopic mechanism of DNA damage searching by hOGG1 | Q34044395 | ||
Phosphate backbone neutralization increases duplex DNA flexibility: a model for protein binding | Q34046682 | ||
Egr-1: is it always immediate and early? | Q34076135 | ||
Measurement of the contributions of 1D and 3D pathways to the translocation of a protein along DNA. | Q34091428 | ||
Absence of a simple code: how transcription factors read the genome | Q34111752 | ||
Macromolecular crowding: an important but neglected aspect of the intracellular environment | Q34141548 | ||
Facilitated diffusion with DNA coiling. | Q37208544 | ||
Artemis is a negative regulator of p53 in response to oxidative stress | Q37216943 | ||
DNA repair in mammalian cells: Base excision repair: the long and short of it. | Q37372532 | ||
An end to 40 years of mistakes in DNA-protein association kinetics? | Q37416158 | ||
The Role of Early Growth Response 1 (EGR1) in Brain Plasticity and Neuropsychiatric Disorders | Q37681295 | ||
Detection of damaged DNA bases by DNA glycosylase enzymes | Q37752315 | ||
Physics of protein–DNA interactions: mechanisms of facilitated target search | Q37813036 | ||
Intrinsically disordered regions as affinity tuners in protein-DNA interactions | Q37932415 | ||
Early growth response 1--a transcription factor in the crossfire of signal transduction cascades | Q37952759 | ||
Classes of fast and specific search mechanisms for proteins on DNA. | Q38025896 | ||
Quantifying transcription factor kinetics: at work or at play? | Q38136333 | ||
Characterization of nonspecific protein-DNA interactions by 1H paramagnetic relaxation enhancement. | Q38335719 | ||
Crowding and confinement effects on protein diffusion in vivo | Q38501075 | ||
Disordered N-Terminal Domain of Human Uracil DNA Glycosylase (hUNG2) Enhances DNA Translocation. | Q38634601 | ||
Investigation of N-Terminal Phospho-Regulation of Uracil DNA Glycosylase Using Protein Semisynthesis | Q38659891 | ||
Hide and seek: How do DNA glycosylases locate oxidatively damaged DNA bases amidst a sea of undamaged bases? | Q39014392 | ||
Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively | Q39725305 | ||
Kinetics of protein-nucleic acid interactions: use of salt effects to probe mechanisms of interaction | Q39727763 | ||
Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity | Q39750512 | ||
Diffusion-controlled macromolecular interactions | Q39821984 | ||
Kinetics of protein-DNA interaction: facilitated target location in sequence-dependent potential | Q40308402 | ||
One- and three-dimensional pathways for proteins to reach specific DNA sites | Q40388353 | ||
Obstacles may facilitate and direct DNA search by proteins | Q40495004 | ||
Timing facilitated site transfer of an enzyme on DNA | Q40531695 | ||
The dynamics of eukaryotic replication initiation: origin specificity, licensing, and firing at the single-molecule level. | Q40541137 | ||
Comparative Effects of Ions, Molecular Crowding, and Bulk DNA on the Damage Search Mechanisms of hOGG1 and hUNG. | Q41299404 | ||
Live-cell p53 single-molecule binding is modulated by C-terminal acetylation and correlates with transcriptional activity. | Q41488339 | ||
A dynamic mode of mitotic bookmarking by transcription factors | Q41809452 | ||
Electrostatic properties of complexes along a DNA glycosylase damage search pathway | Q41844655 | ||
Generalized facilitated diffusion model for DNA-binding proteins with search and recognition states | Q42171094 | ||
Common crowding agents have only a small effect on protein-protein interactions | Q42629355 | ||
Protein-protein association in polymer solutions: from dilute to semidilute to concentrated | Q42826492 | ||
MEASUREMENT of Protein 53 Diffusion Coefficient in Live HeLa Cells Using Raster Image Correlation Spectroscopy (RICS). | Q42847084 | ||
Search by proteins for their DNA target site: 2. The effect of DNA conformation on the dynamics of multidomain proteins | Q42999182 | ||
Macromolecular diffusion in crowded solutions | Q43006058 | ||
Direct visualization of a DNA glycosylase searching for damage | Q43943026 | ||
An evolutionary analysis of the helix-hairpin-helix superfamily of DNA repair glycosylases | Q44495541 | ||
Proteolytic degradation of the nuclear isoform of uracil-DNA glycosylase occurs during the S phase of the cell cycle | Q44844586 | ||
Stopped-flow fluorescence kinetic study of protein sliding and intersegment transfer in the target DNA search process | Q44948975 | ||
p53 linear diffusion along DNA requires its C terminus | Q45138454 | ||
Structures of end products resulting from lesion processing by a DNA glycosylase/lyase | Q45195481 | ||
Correlated cleavage of damaged DNA by bacterial and human 8-oxoguanine-DNA glycosylases | Q46450712 | ||
Measurement of nanoscale DNA translocation by uracil DNA glycosylase in human cells | Q47156991 | ||
Effect of crowding on protein-protein association rates: fundamental differences between low and high mass crowding agents | Q47736902 | ||
Putting p53 in Context | Q47833426 | ||
Backbone (1)H, (13)C and (15)N chemical shift assignment of full-length human uracil DNA glycosylase UNG2. | Q47844295 | ||
The Disordered Linker in p53 Participates in Nonspecific Binding to and One-Dimensional Sliding along DNA Revealed by Single-Molecule Fluorescence Measurements | Q47912513 | ||
A Requirement for the Immediate Early Gene zif268 in Reconsolidation of Recognition Memory after Retrieval | Q48143332 | ||
Visualizing transcription factor dynamics in living cells. | Q48148108 | ||
Single-particle trajectories reveal two-state diffusion-kinetics of hOGG1 proteins on DNA. | Q50089806 | ||
The Human Transcription Factors | Q50098118 | ||
Spatial distribution of competing ions around DNA in solution. | Q51543158 | ||
Regulation of DNA binding of p53 by its C-terminal domain. | Q51624447 | ||
Activation of p53 Facilitates the Target Search in DNA by Enhancing the Target Recognition Probability. | Q51707194 | ||
The effects of intersegmental transfers on target location by proteins. | Q51856018 | ||
Diffusion-driven mechanisms of protein translocation on nucleic acids. 1. Models and theory. | Q52732418 | ||
One-Dimensional Sliding of p53 Along DNA Is Accelerated in the Presence of Ca(2+) or Mg(2+) at Millimolar Concentrations. | Q53190488 | ||
Dynamic interactions of p53 with DNA in solution by time-lapse atomic force microscopy | Q57188522 | ||
Imaging dynamic and selective low-complexity domain interactions that control gene transcription | Q57979132 | ||
Direct Observation of Enhanced Translocation of a Homeodomain between DNA Cognate Sites by NMR Exchange Spectroscopy | Q58443617 | ||
Facilitated diffusion during catalysis by EcoRI endonuclease. Nonspecific interactions in EcoRI catalysis | Q70105786 | ||
Salt dependence of the kinetics of the lac repressor-operator interaction: role of nonoperator deoxyribonucleic acid in the association reaction | Q70174498 | ||
Egr-1-induced endothelial gene expression: a common theme in vascular injury | Q70990718 | ||
Protein sliding along DNA: dynamics and structural characterization | Q82851590 | ||
Dynamics of E. coli single stranded DNA binding (SSB) protein-DNA complexes | Q88194032 | ||
NMR-based investigations into target DNA search processes of proteins | Q88647725 | ||
N-terminal domain of human uracil DNA glycosylase (hUNG2) promotes targeting to uracil sites adjacent to ssDNA-dsDNA junctions | Q89149291 | ||
Distinguishing Specific and Nonspecific Complexes of Alkyladenine DNA Glycosylase | Q89234745 | ||
Intrinsically disordered domain of tumor suppressor p53 facilitates target search by ultrafast transfer between different DNA strands | Q89475634 | ||
New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins | Q90596330 | ||
Uracil in DNA--occurrence, consequences and repair | Q34165028 | ||
A model for the mediation of processivity of DNA-targeting proteins by nonspecific binding: dependence on DNA length and presence of obstacles | Q34189290 | ||
Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a chromatin lattice | Q34193203 | ||
DNA search efficiency is modulated by charge composition and distribution in the intrinsically disordered tail | Q34397079 | ||
Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. | Q34407601 | ||
Connecting the dots: the effects of macromolecular crowding on cell physiology. | Q34454279 | ||
A single-molecule characterization of p53 search on DNA | Q34490695 | ||
Probing transcription factor dynamics at the single-molecule level in a living cell | Q34631575 | ||
The DNA binding activity of p53 displays reaction-diffusion kinetics. | Q34680338 | ||
Interpreting protein/DNA interactions: distinguishing specific from non-specific and electrostatic from non-electrostatic components | Q34779522 | ||
Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA. | Q34782000 | ||
Dynamics of uracil and 5-fluorouracil in DNA. | Q34813962 | ||
Probing the DNA structural requirements for facilitated diffusion. | Q35001072 | ||
Awakening guardian angels: drugging the p53 pathway | Q35014385 | ||
Intra- and intermolecular translocation of the bi-domain transcription factor Oct1 characterized by liquid crystal and paramagnetic NMR. | Q35021954 | ||
A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex. | Q35108052 | ||
NMR structural and kinetic characterization of a homeodomain diffusing and hopping on nonspecific DNA. | Q35108070 | ||
Protein self-diffusion in crowded solutions | Q35123303 | ||
A mechanistic perspective on the chemistry of DNA repair glycosylases | Q35171800 | ||
Exploring translocation of proteins on DNA by NMR | Q35517617 | ||
Molecular crowding enhances facilitated diffusion of two human DNA glycosylases | Q35562174 | ||
Determining the Locations of Ions and Water around DNA from X-Ray Scattering Measurements | Q35666406 | ||
Single Cell Assay for Molecular Diagnostics and Medicine: Monitoring Intracellular Concentrations of Macromolecules by Two-photon Fluorescence Lifetime Imaging | Q35686254 | ||
Quantitative Aspects of Single Molecule Microscopy | Q35826411 | ||
Surf the post-translational modification network of p53 regulation | Q35967111 | ||
Balancing between affinity and speed in target DNA search by zinc-finger proteins via modulation of dynamic conformational ensemble | Q36079071 | ||
Dancing on DNA: kinetic aspects of search processes on DNA | Q36110835 | ||
Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. | Q36127010 | ||
Influence of quasi-specific sites on kinetics of target DNA search by a sequence-specific DNA-binding protein | Q36272461 | ||
Repair of Alkylation Damage in Eukaryotic Chromatin Depends on Searching Ability of Alkyladenine DNA Glycosylase | Q36496110 | ||
Evidence for a common mode of transcription factor interaction with chromatin as revealed by improved quantitative fluorescence recovery after photobleaching. | Q36510561 | ||
Optical Methods to Study Protein-DNA Interactions in Vitro and in Living Cells at the Single-Molecule Level. | Q36656166 | ||
Tumor suppressor p53 slides on DNA with low friction and high stability | Q36717623 | ||
Spatial effects on the speed and reliability of protein-DNA search | Q36740092 | ||
P433 | issue | 23 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 11298-11323 | |
P577 | publication date | 2018-10-31 | |
P1433 | published in | Chemical Reviews | Q900502 |
P1476 | title | Facilitated Diffusion Mechanisms in DNA Base Excision Repair and Transcriptional Activation | |
P478 | volume | 118 |
Q92835742 | Understanding biochemical processes in the presence of sub-diffusive behavior of biomolecules in solution and living cells | cites work | P2860 |
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