Behavioral evidence for the differential regulation of p-p38 MAPK and p-NF-κB in rats with trigeminal neuropathic pain.

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Behavioral evidence for the differential regulation of p-p38 MAPK and p-NF-κB in rats with trigeminal neuropathic pain. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1026538339
P356DOI10.1186/1744-8069-7-57
P932PMC publication ID3164622
P698PubMed publication ID21816109
P5875ResearchGate publication ID51546710

P2093author name stringSung K Kim
Dong K Ahn
Min J Kim
Min K Lee
Yong C Bae
Min K Park
Jae S Park
Seung R Han
P2860cites workGlial cells and chronic painQ24603427
NF-kappaB in neuronal plasticity and neurodegenerative disordersQ34131754
Activated microglia contribute to the maintenance of chronic pain after spinal cord injury.Q34515061
Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain.Q35078217
Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesiaQ35677224
Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanismQ36099893
Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injuryQ36402894
Protein kinases as potential targets for the treatment of pathological painQ36646044
p38 MAPK signaling in oral-related diseasesQ36919722
Glia in pathological pain: a role for fractalkineQ37189198
Neuron-glia crosstalk gets serious: role in pain hypersensitivityQ37265977
Alteration of primary afferent activity following inferior alveolar nerve transection in rats.Q39312064
Activation of glia and microglial p38 MAPK in medullary dorsal horn contributes to tactile hypersensitivity following trigeminal sensory nerve injury.Q42491218
Activation of astrocytes in the spinal cord contributes to the development of bilateral allodynia after peripheral nerve injury in ratsQ42864343
Inhibition of NF-kappaB prevents mechanical allodynia induced by spinal ventral root transection and suppresses the re-expression of Nav1.3 in DRG neurons in vivo and in vitro.Q42880746
Spinal microglial expression and mechanical hypersensitivity in a postoperative pain model: comparison with a neuropathic pain modelQ43293716
Intratrigeminal ganglionic injection of LPA causes neuropathic pain-like behavior and demyelination in ratsQ43295901
Celecoxib loses its anti-inflammatory efficacy at high doses through activation of NF-kappaB.Q43654472
Effect of antisense knock-down of alpha(2a)- and alpha(2c)-adrenoceptors on the antinociceptive action of clonidine on trigeminal nociception in the rat.Q44050815
Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats.Q44306964
p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.Q44451943
A highly selective inhibitor of I kappa B kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in miceQ44586798
Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injuryQ44675650
Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.Q45146987
Central glucocorticoid receptors modulate the expression and function of spinal NMDA receptors after peripheral nerve injury.Q45221824
Compression of the trigeminal ganglion produces prolonged nociceptive behavior in rats.Q45899069
Central cyclooxygenase inhibitors reduced IL-1beta-induced hyperalgesia in temporomandibular joint of freely moving ratsQ46648867
Involvement of spinal cord nuclear factor kappaB activation in rat models of proinflammatory cytokine-mediated pain facilitationQ46785515
Increased activation of nuclear factor kappa B in rat lumbar dorsal root ganglion neurons following partial sciatic nerve injuriesQ47836336
Early dexamethasone relieves trigeminal neuropathic painQ48348412
Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury modelQ48578483
Alteration of medullary dorsal horn neuronal activity following inferior alveolar nerve transection in ratsQ48697449
Expression of central glucocorticoid receptors after peripheral nerve injury contributes to neuropathic pain behaviors in rats.Q48838823
Activation of Src-family kinases in spinal microglia contributes to mechanical hypersensitivity after nerve injury.Q51979971
Blockade of central cyclooxygenase (COX) pathways enhances the cannabinoid-induced antinociceptive effects on inflammatory temporomandibular joint (TMJ) nociception.Q53577374
Interleukin-18-mediated microglia/astrocyte interaction in the spinal cord enhances neuropathic pain processing after nerve injury.Q54785181
Activation of NF-κB in the mouse spinal cord following sciatic nerve transectionQ62907120
Alteration of the second branch of the trigeminal nerve activity following inferior alveolar nerve transection in ratsQ80556062
Intracisternal administration of mitogen-activated protein kinase inhibitors reduced mechanical allodynia following chronic constriction injury of infraorbital nerve in ratsQ80585963
Thiamine and cyanocobalamin relieve neuropathic pain in rats: synergy with dexamethasoneQ83150487
P4510describes a project that usesImageJQ1659584
P921main subjectNF-κBQ411114
neuropathic painQ2798704
P304page(s)57
P577publication date2011-08-05
P1433published inMolecular PainQ15766244
P1476titleBehavioral evidence for the differential regulation of p-p38 MAPK and p-NF-κB in rats with trigeminal neuropathic pain.
P478volume7

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cites work (P2860)
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Q33647456Chronic tooth pulp inflammation induces persistent expression of phosphorylated ERK (pERK) and phosphorylated p38 (pp38) in trigeminal subnucleus caudalis
Q91706058Co-Administered Low Doses Of Ibuprofen And Dexamethasone Produce Synergistic Antinociceptive Effects On Neuropathic Mechanical Allodynia In Rats
Q64057223Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway
Q60921672Crosstalk between NFκB-dependent astrocytic CXCL1 and neuron CXCR2 plays a role in descending pain facilitation
Q52148661Glial activation in the periaqueductal gray promotes descending facilitation of neuropathic pain through the p38 MAPK signaling pathway.
Q64057634Increased cerebral nuclear factor kappa B in a complex regional pain syndrome rat model: possible relationship between peripheral injury and the brain
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Q64260574Lavender ( Mill.) Essential Oil Alleviates Neuropathic Pain in Mice With Spared Nerve Injury
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