Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes

scientific article

Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MOLIMM.2010.07.014
P932PMC publication ID4372152
P698PubMed publication ID20728939

P2093author name stringMichael Martin
Denis F Kinane
Jiawei Zhao
Johnah C Galicia
Manjunatha R Benakanakere
Kavita B Hosur
P2860cites workSignaling by target of rapamycin proteins in cell growth controlQ24522447
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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responsesQ27860685
TOR signaling in growth and metabolismQ27860757
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Signal transduction by the JNK group of MAP kinasesQ28142592
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathwayQ28190704
Triggering the interferon antiviral response through an IKK-related pathwayQ28191761
Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKRQ28212718
Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif siteQ28243447
Activation of innate immune defense mechanisms by signaling through RIG-I/IPS-1 in intestinal epithelial cellsQ28251813
CREB is a regulatory target for the protein kinase Akt/PKBQ28289946
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates AktQ29547767
Interleukin-12 and the regulation of innate resistance and adaptive immunityQ29614602
Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.Q30440717
In vitro modeling of host-parasite interactions: the 'subgingival' biofilm challenge of primary human epithelial cellsQ33521518
Sphingosine kinase-1 is required for toll mediated beta-defensin 2 induction in human oral keratinocytesQ33634084
Immunoregulatory functions of mTOR inhibition.Q33761278
Toll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2.Q33771582
The evolution and genetics of innate immunityQ34205534
The rapamycin-sensitive signal transduction pathway as a target for cancer therapyQ34293622
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Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.Q34443426
PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiationQ34653250
Phosphorylation of c-jun mediated by MAP kinases.Q34947174
Tor signalling in bugs, brain and brawnQ35058522
Inferences, questions and possibilities in Toll-like receptor signallingQ35829752
Sensing of viral infection and activation of innate immunity by toll-like receptor 3Q36422519
Epstein-Barr virus in oral diseasesQ36530296
Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cellsQ36787558
A gene signature-based approach identifies mTOR as a regulator of p73.Q36898974
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translationQ36971030
P. gingivalis interactions with epithelial cellsQ36991989
TLR3: interferon induction by double-stranded RNA including poly(I:C).Q37080631
The host cytokine response to Porphyromonas gingivalis is modified by gingipainsQ37279079
Modulation of TLR2 protein expression by miR-105 in human oral keratinocytesQ37371743
The multiple facets of mTOR in immunity.Q37441725
Rapamycin inhibits proliferation of estrogen-receptor-positive breast cancer cellsQ40207662
Toll-like receptor 3 agonist poly(I:C)-induced antiviral response in human corneal epithelial cellsQ40327809
Interleukin-1beta modulates proinflammatory cytokine production in human epithelial cellsQ41790319
Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.Q42431545
Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.Q42995176
The pharmacology of mTOR inhibitionQ46041824
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cellsQ46314249
The TSC-mTOR signaling pathway regulates the innate inflammatory responseQ46321173
Sphingosine 1-phosphate 1 and TLR4 mediate IFN-beta expression in human gingival epithelial cellsQ46798631
Gingival epithelial cells heterozygous for Toll-like receptor 4 polymorphisms Asp299Gly and Thr399ile are hypo-responsive to Porphyromonas gingivalis.Q46911771
Role of toll-like receptor 3, RIG-I, and MDA5 in the expression of mesothelial IL-8 induced by viral RNA.Q47719648
Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells.Q54771591
Translational control of the innate immune response through IRF-7Q57203299
Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cellsQ61276176
The immunosuppressant rapamycin induces inactivation of p70s6k through dephosphorylation of a novel set of sitesQ72865321
Double-stranded RNA induces production of RANTES and IL-8 by human nasal fibroblastsQ81410484
P433issue1-3
P921main subjectsirolimusQ32089
toll-like receptorQ408004
keratinocyteQ1473931
P304page(s)294-304
P577publication date2010-08-21
P1433published inMolecular ImmunologyQ6895954
P1476titleMammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes
P478volume48

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cites work (P2860)
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