| scholarly article | Q13442814 |
| P2093 | author name string | Xiaoxia Li | |
| Bryan R G Williams | |||
| Zhengfan Jiang | |||
| Maryam Zamanian-Daryoush | |||
| Huiqing Nie | |||
| Aristobolo M Silva | |||
| P2860 | cites work | Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene | Q22299417 |
| TRAF6 is a signal transducer for interleukin-1 | Q28291934 | ||
| The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. | Q40919510 | ||
| P433 | issue | 19 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | interleukins | Q194908 |
| toll-like receptor | Q408004 | ||
| P304 | page(s) | 16713-9 | |
| P577 | publication date | 2003-05-09 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR | |
| P478 | volume | 278 |
| Q40628527 | A Dominant Role of Toll-Like Receptor 4 in the Signaling of Apoptosis in Bacteria-Faced Macrophages |
| Q97643251 | A benzimidazole inhibitor attenuates sterile inflammation induced in a model of systemic autoinflammation in female mice |
| Q36229362 | A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity |
| Q33759787 | A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-β factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling |
| Q50291752 | Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex |
| Q36345961 | Activation of Toll-like receptors 2, 3, and 4 on human melanoma cells induces inflammatory factors |
| Q50291753 | Activation of recruited TAK1 within the activated TLR3 complex |
| Q37523013 | Alternaria inhibits double-stranded RNA-induced cytokine production through Toll-like receptor 3. |
| Q35085718 | An essential role for TAK1 in the contact hypersensitivity response |
| Q38382435 | Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility |
| Q24299892 | Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling |
| Q34155757 | Asthma is associated with multiple alterations in anti-viral innate signalling pathways |
| Q45385575 | B-cell-activating factor expressions in salivary epithelial cells after dsRNA virus infection depends on RNA-activated protein kinase activation |
| Q38828398 | Bombesin Receptor-Activated Protein (BRAP) Modulates NF-κB Activation in Bronchial Epithelial Cells by Enhancing HDAC Activity |
| Q39795004 | Characteristics of alpha/beta interferon induction after infection of murine fibroblasts with wild-type and mutant alphaviruses. |
| Q35192859 | Cleavage of the adaptor protein TRIF by enterovirus 71 3C inhibits antiviral responses mediated by Toll-like receptor 3. |
| Q37728405 | Cloning and characterization of DULP, a novel ubiquitin-like molecule from human dendritic cells |
| Q41812228 | Complete dependence on IRAK4 kinase activity in TLR2, but not TLR4, signaling pathways underlies decreased cytokine production and increased susceptibility to Streptococcus pneumoniae infection in IRAK4 kinase-inactive mice |
| Q35630534 | Controlling the Toll road to dendritic cell polarization |
| Q39726296 | CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion |
| Q45182335 | Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2. |
| Q90516129 | De novo EIF2AK1 and EIF2AK2 Variants Are Associated with Developmental Delay, Leukoencephalopathy, and Neurologic Decompensation |
| Q37452096 | Dephosphorylation of eIF2alpha mediated by the gamma134.5 protein of herpes simplex virus 1 facilitates viral neuroinvasion |
| Q40110941 | Differences between lipopolysaccharide and double-stranded RNA in innate immune responses of BV2 microglial cells |
| Q39852234 | Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide. |
| Q35799552 | Differential responses of normal human melanocytes to intra- and extracellular dsRNA |
| Q30498322 | Differential utilization of NF-kappaB RELA and RELB in response to extracellular versus intracellular polyIC stimulation in HT1080 cells |
| Q37547206 | Direct, interferon-independent activation of the CXCL10 promoter by NF-κB and interferon regulatory factor 3 during hepatitis C virus infection |
| Q40555886 | Double-stranded RNA activates RANTES gene transcription through co-operation of nuclear factor-kappaB and interferon regulatory factors in human airway epithelial cells |
| Q34788072 | Double-stranded RNA induces shedding of the 34-kDa soluble TNFR1 from human airway epithelial cells via TLR3-TRIF-RIP1-dependent signaling: roles for dual oxidase 2- and caspase-dependent pathways |
| Q28578265 | Double-stranded RNA signals antiviral and inflammatory programs and dysfunctional glutamate transport in TLR3-expressing astrocytes |
| Q28548490 | Embryonic Stem Cell Growth Factors Regulate eIF2α Phosphorylation |
| Q34347972 | Endotoxin recognition: in fish or not in fish? |
| Q42489453 | Evolution of vertebrate immunity: sequence and functional analysis of the SEFIR domain family member Act1. |
| Q39818388 | Expression of tak1 and tram induces synergistic pro-inflammatory signalling and adjuvants DNA vaccines |
| Q45391769 | Expressional induction of Paralichthys olivaceus cathepsin B gene in response to virus, poly I:C and lipopolysaccharide |
| Q35982277 | Genetic analysis of innate immunity: TIR adapter proteins in innate and adaptive immune responses |
| Q36149855 | Genetic analysis of innate immunity: identification and function of the TIR adapter proteins |
| Q80149163 | Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation |
| Q35407394 | Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production |
| Q41585188 | High-affinity interaction between IKKbeta and NEMO. |
| Q24311379 | Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12 |
| Q24294677 | Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses |
| Q36938505 | Human variability in innate immunity. |
| Q45395915 | Hyaluronan production in synoviocytes as a consequence of viral infections: HAS1 activation by Epstein-Barr virus and synthetic double- and single-stranded viral RNA analogs |
| Q28249343 | IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination |
| Q26746467 | Immune Activation in the Liver by Nucleic Acids |
| Q24672548 | Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action |
| Q36966559 | Impact of the Type I Interferon Receptor on the Global Gene Expression Program During the Course of Dendritic Cell Maturation Induced by Polyinosinic Polycytidylic Acid |
| Q54112903 | Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation. |
| Q40296049 | Induction of chemokine and cytokine genes in astrocytes following infection with Theiler's murine encephalomyelitis virus is mediated by the Toll-like receptor 3. |
| Q35829752 | Inferences, questions and possibilities in Toll-like receptor signalling |
| Q37320983 | Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated, but not rhinovirus infected, primary human airway smooth muscle |
| Q40327930 | Innate immunity at the mucosal surface: role of toll-like receptor 3 and toll-like receptor 9 in cervical epithelial cell responses to microbial pathogens |
| Q34058607 | Inosine-containing RNA is a novel innate immune recognition element and reduces RSV infection |
| Q36557550 | Interferon action and the double-stranded RNA-dependent enzymes ADAR1 adenosine deaminase and PKR protein kinase |
| Q37098917 | Interferon β (IFN-β) Production during the Double-stranded RNA (dsRNA) Response in Hepatocytes Involves Coordinated and Feedforward Signaling through Toll-like Receptor 3 (TLR3), RNA-dependent Protein Kinase (PKR), Inducible Nitric Oxide Synthase (i |
| Q47571636 | Interferon-Stimulated Genes as Enhancers of Antiviral Innate Immune Signaling. |
| Q27490770 | Intrinsic Cellular Defenses against Virus Infection by Antiviral Type I Interferon |
| Q30010041 | Large G3BP-induced granules trigger eIF2α phosphorylation |
| Q37099483 | Live Borrelia burgdorferi spirochetes elicit inflammatory mediators from human monocytes via the Toll-like receptor signaling pathway |
| Q98172163 | Loss of Function Genetic Screen Identifies ATM Kinase as a Positive Regulator of TLR3-Mediated NF-κB Activation |
| Q37412380 | Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virus |
| Q36756108 | MCPIP1 negatively regulates toll-like receptor 4 signaling and protects mice from LPS-induced septic shock |
| Q35213190 | Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes |
| Q41911561 | Mechanisms of dexamethasone-mediated inhibition of Toll-like receptor signaling induced by Neisseria meningitidis and Streptococcus pneumoniae |
| Q34554357 | Modulation of Toll-interleukin 1 receptor mediated signaling |
| Q43699807 | Modulation of double-stranded RNA-activated protein kinase in insulin sensitive tissues of obese humans. |
| Q27649460 | Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20 |
| Q38876498 | Molecular mechanisms of regulation of Toll-like receptor signaling |
| Q40040720 | MyD88 functions as a negative regulator of TLR3/TRIF-induced corneal inflammation by inhibiting activation of c-Jun N-terminal kinase |
| Q36435841 | NFkappaB in neurons? The uncertainty principle in neurobiology |
| Q55333937 | Neutrophil TLR4 and PKR are targets of breast cancer cell glycosaminoglycans and effectors of glycosaminoglycan-induced APRIL secretion. |
| Q39403634 | Norkurarinol inhibits toll-like receptor 3 (TLR3)-mediated pro-inflammatory signaling pathway and rotavirus replication |
| Q41435037 | Novel expression and regulation of TIMP-1 in Epstein Barr virus-infected cells and its impact on cell survival |
| Q34361655 | Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling |
| Q59349689 | PCR array profiling of antiviral genes in human embryonic kidney cells expressing human coronavirus OC43 structural and accessory proteins |
| Q61449861 | PKR: A Kinase to Remember |
| Q61796005 | PLCβ2 negatively regulates the inflammatory response to virus infection by inhibiting phosphoinositide-mediated activation of TAK1 |
| Q24643034 | Pathogen recognition and inflammatory signaling in innate immune defenses |
| Q28511245 | Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production |
| Q34756285 | Perturbations of mucosal homeostasis through interactions of intestinal microbes with myeloid cells |
| Q50291754 | Phosphorylated TAK1 dissociates from the TLR3 receptor complex |
| Q50291843 | Phosphorylated TAK1 leaves activated TLR receptor complex |
| Q36476232 | Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia |
| Q37195948 | Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway |
| Q24298263 | Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation |
| Q36869485 | Protein kinase R-dependent regulation of interleukin-10 in response to double-stranded RNA. |
| Q24671766 | RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection |
| Q28288337 | RIP1, a kinase on the crossroads of a cell's decision to live or die |
| Q36001067 | Reading the viral signature by Toll-like receptors and other pattern recognition receptors |
| Q57817467 | Regulation of NLRP3 Inflammasome by Phosphorylation |
| Q39465762 | Regulation of the p38 mitogen-activated protein kinase and dual-specificity phosphatase 1 feedback loop modulates the induction of interleukin 6 and 8 in cells infected with coronavirus infectious bronchitis virus. |
| Q28249812 | Resolvin D1 attenuates polyinosinic-polycytidylic acid-induced inflammatory signaling in human airway epithelial cells via TAK1 |
| Q37736941 | Review: Toll-like receptors and NOD-like receptors in pulmonary antibacterial immunity |
| Q45345604 | Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation |
| Q37236668 | Role of non-degradative ubiquitination in interleukin-1 and toll-like receptor signaling. |
| Q28571181 | Rotavirus double-stranded RNA induces apoptosis and diminishes wound repair in rat intestinal epithelial cells |
| Q24301289 | SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms |
| Q24316441 | SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling |
| Q37559671 | Sam68 is a regulator of Toll-like receptor signaling |
| Q39873428 | Short double-stranded RNAs of specific sequence activate ribosomal TAK1-D and induce a global inhibition of translation |
| Q28283196 | Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4 |
| Q40433595 | Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes |
| Q42806112 | Specific inhibition of the PKR-mediated antiviral response by the murine cytomegalovirus proteins m142 and m143. |
| Q28504462 | TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo |
| Q35605453 | TLR3 expression correlates with apoptosis, proliferation and angiogenesis in hepatocellular carcinoma and predicts prognosis |
| Q36675252 | TLR3 immunity to infection in mice and humans |
| Q39331461 | TLR3-dependent immune regulatory functions of human mesangial cells |
| Q40355488 | TLR3-mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: differential signaling mechanisms of TLR3-induced IP-10 and IL-8 gene expression. |
| Q37978745 | TLR4 polymorphisms and disease susceptibility |
| Q56940858 | TLR8-mediated NF-κB and JNK Activation Are TAK1-independent and MEKK3-dependent |
| Q24338458 | TRAF family proteins link PKR with NF-kappa B activation |
| Q28593493 | TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation |
| Q36332924 | TRIM56 is an essential component of the TLR3 antiviral signaling pathway |
| Q34046154 | The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses |
| Q39223220 | The Impact of the Interferon/TNF-Related Apoptosis-Inducing Ligand Signaling Axis on Disease Progression in Respiratory Viral Infection and Beyond |
| Q93264329 | The PPARα agonist fenofibrate attenuates disruption of dopamine function in a maternal immune activation rat model of schizophrenia |
| Q27487554 | The RNA-activated Protein Kinase Enhances the Induction of Interferon- and Apoptosis Mediated by Cytoplasmic RNA Sensors |
| Q64229641 | The TLR3 Agonist Poly Inosinic:Cytidylic Acid Significantly Augments the Therapeutic Activity of an Anti-CD7 Immunotoxin for Human T-cell Leukaemia |
| Q39370363 | The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide. |
| Q40167543 | The caspase-generated fragments of PKR cooperate to activate full-length PKR and inhibit translation |
| Q39515189 | The innate antiviral immune system of the cat: molecular tools for the measurement of its state of activation |
| Q40633816 | The interleukin 1 (IL-1) receptor accessory protein Toll/IL-1 receptor domain: analysis of putative interaction sites in vitro mutagenesis and molecular modeling |
| Q36384200 | The kinase complex responsible for IRF-3-mediated IFN-beta production in myeloid dendritic cells (mDC). |
| Q39985197 | The scaffold MyD88 acts to couple protein kinase Cepsilon to Toll-like receptors. |
| Q37097294 | Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies. |
| Q42210295 | Toll-like receptor 3 inhibits Newcastle disease virus replication through activation of pro-inflammatory cytokines and the type-1 interferon pathway |
| Q35037100 | Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals |
| Q33984176 | Toll-like receptor 3 is induced by and mediates antiviral activity against rhinovirus infection of human bronchial epithelial cells |
| Q24311833 | Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta |
| Q35697425 | Toll-like receptor 3: a link between toll-like receptor, interferon and viruses |
| Q39442360 | Toll-like receptor ligands directly promote activated CD4+ T cell survival |
| Q36945037 | Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccines |
| Q35189960 | Toll-like receptor signaling |
| Q35028032 | Toll-like receptor, RIG-I-like receptors and the NLRP3 inflammasome: key modulators of innate immune responses to double-stranded RNA viruses. |
| Q35172878 | Toll-like receptors are potential therapeutic targets in rheumatoid arthritis |
| Q37265030 | Toll-like receptors in skin infections and inflammatory diseases. |
| Q35738175 | Toll-like receptors: function and roles in lung disease |
| Q24297037 | Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3... |
| Q38813906 | Transcription Factor Runx3 Is Induced by Influenza A Virus and Double-Strand RNA and Mediates Airway Epithelial Cell Apoptosis |
| Q40633146 | Viral Induction of Inflammatory Cytokines in Human Epithelial Cells Follows a p38 Mitogen-Activated Protein Kinase-Dependent but NF-κB-Independent Pathway |
| Q98771780 | When Innate Immunity Meets Angiogenesis-The Role of Toll-Like Receptors in Endothelial Cells and Pulmonary Hypertension |
| Q39941925 | p53 regulates Toll-like receptor 3 expression and function in human epithelial cell lines |
| Q36550881 | siRNA and isRNA: two edges of one sword |
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