Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies.

scientific article published on 27 February 2009

Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1000315
P932PMC publication ID2642728
P698PubMed publication ID19247444
P5875ResearchGate publication ID24044651

P50authorMonique LafonQ54470462
P2093author name stringPascal Roux
Anne Danckaert
Christophe Préhaud
Jean-Pierre Bourgeois
Anne-Marie Le Sourd
Mireille Lafage
Françoise Mégret
Pauline Ménager
P2860cites workToll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...Q24297037
TLR signaling tailors innate immune responses in human microglia and astrocytesQ57041985
Polyinosinic Acid Is a Ligand for Toll-like Receptor 3Q63363426
Use of a monoclonal antibody for quantitation of rabies vaccine glycoprotein by enzyme immunoassayQ69913632
The interaction of mammalian reoviruses with the cytoskeleton of monkey kidney CV-1 cellsQ70679241
Standard conformations of beta-arches in beta-solenoid proteinsQ83035160
Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signalingQ24297831
Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-betaQ24311833
A family of human receptors structurally related to Drosophila TollQ24321888
LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIFQ24672442
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3Q27860854
Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotectiveQ28185660
Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKRQ28212718
Aggresomes and autophagy generate sites for virus replicationQ28239704
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomesQ28270473
Aggresomes: a cellular response to misfolded proteinsQ28292275
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6Q28584723
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathwayQ28592087
Aggresomes, inclusion bodies and protein aggregationQ29615253
Virus factories: associations of cell organelles for viral replication and morphogenesisQ30051798
Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosomeQ30442117
Identities of sequestered proteins in aggregates from cells with induced polyglutamine expressionQ30987442
The neural cell adhesion molecule is a receptor for rabies virusQ33783788
Interaction of Theiler's virus with intermediate filaments of infected cellsQ33785960
Antisense RNA: function and fate of duplex RNA in cells of higher eukaryotes.Q34010093
mRNA is an endogenous ligand for Toll-like receptor 3.Q34290592
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activationQ34311133
Rabies: interactions between neurons and viruses. A review of the history of Negri inclusion bodiesQ34396750
NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN inductionQ34586735
Toll-like receptor 3 is a potent negative regulator of axonal growth in mammalsQ35037100
Monoclonal antibodies to double-stranded RNA as probes of RNA structure in crude nucleic acid extractsQ35766226
Transcriptional signaling by double-stranded RNA: role of TLR3.Q36055866
Sensing of viral infection and activation of innate immunity by toll-like receptor 3Q36422519
Rabies viral mechanisms to escape the IFN system: the viral protein P interferes with IRF-3, Stat1, and PML nuclear bodiesQ36475423
Structure and function of herpesvirus genomes. I. comparison of five HSV-1 and two HSV-2 strains by cleavage their DNA with eco R I restriction endonucleaseQ36533141
Sendai virus C protein plays a role in restricting PKR activation by limiting the generation of intracellular double-stranded RNA.Q36933945
Aggresomes and pericentriolar sites of virus assembly: cellular defense or viral design?Q36951982
Accumulation and clearance of alpha-synuclein aggregates demonstrated by time-lapse imagingQ39992222
The innate immune facet of brain: human neurons express TLR-3 and sense viral dsRNA.Q40211782
TLR3 can directly trigger apoptosis in human cancer cells.Q40296182
Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cellsQ40327372
Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferonQ40368047
Subcellular localization of Toll-like receptor 3 in human dendritic cellsQ40636721
Production of human CNS neurons from embryonal carcinoma cells using a cell aggregation methodQ40812771
Studies on unusual cytoplasmic structures which contain rabies virus envelope proteinsQ41171925
Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigenQ41313592
Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neuronsQ41625581
Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA virusesQ42425012
Preferential expression and function of Toll-like receptor 3 in human astrocytesQ42472896
Persistent infection of BHK21/WI-2 cells with rubella virus and characterization of rubella variantsQ42801732
Characterization and dynamics of aggresome formation by a cytosolic GFP-chimeraQ42870983
Turning teratocarcinoma cells into neurons: rapid differentiation of NT-2 cells in floating spheresQ44414268
Cloning of TLR3 isoformQ44876968
The cytoplasmic 'linker region' in Toll-like receptor 3 controls receptor localization and signalingQ44958632
Formation of aggresome-like structures in herpes simplex virus type 2-infected cells and a potential role in virus assembly.Q45046123
Rabies virus entry into endosomes in IMR-32 human neuroblastoma cellsQ45753751
Detection of virus infection in plants and differentiation between coexisting viruses by monoclonal antibodies to double-stranded RNA.Q45780510
Antiviral activity of monoclonal antibodies specific for the internal proteins N and NS of rabies virusQ45847791
Localization and immunological characterization of antigenic domains of the rabies virus internal N and NS proteinsQ45847886
Cytoplasmic dynein/dynactin mediates the assembly of aggresomesQ46583953
Huntingtin and mutant SOD1 form aggregate structures with distinct molecular properties in human cellsQ46863333
Immunohistochemical localization of endothelial and inducible nitric oxide synthase within neurons of cattle with rabiesQ47370069
Expression of Toll-like receptor 3 in the human cerebellar cortex in rabies, herpes simplex encephalitis, and other neurological diseasesQ48459159
Quantitative study of the infection in brain neurons in human rabiesQ48750610
Selective role for the p55 Kd TNF-alpha receptor in immune unresponsiveness induced by an acute viral encephalitisQ49117882
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P921main subjectrabiesQ39222
rabies virusQ698976
toll-like receptorQ408004
P304page(s)e1000315
P577publication date2009-02-27
P1433published inPLOS PathogensQ283209
P1476titleToll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies
P478volume5

Reverse relations

cites work (P2860)
Q37779726A hitchhiker's guide to the nervous system: the complex journey of viruses and toxins.
Q36086238Actin-Modulating Protein Cofilin Is Involved in the Formation of Measles Virus Ribonucleoprotein Complex at the Perinuclear Region
Q34626059Activation of the type I interferon pathway is enhanced in response to human neuronal differentiation.
Q24300579Ambivalent role of the innate immune response in rabies virus pathogenesis
Q42270304An amino acid of human parainfluenza virus type 3 nucleoprotein is critical for template function and cytoplasmic inclusion body formation
Q36978839Cellular chaperonin CCTγ contributes to rabies virus replication during infection
Q33958086Characterization of Toll-like receptors 1-10 in spotted hyenas
Q40862930Correlation of inducible nitric oxide synthase (iNOS) inhibition with TNF-α, caspase-1, FasL and TLR-3 in pathogenesis of rabies in mouse model
Q38211810Current status of rabies and prospects for elimination
Q90093120DNA Sensors' Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection
Q38515936Dynamics of virus-receptor interactions in virus binding, signaling, and endocytosis
Q35312002Establishment of Myotis myotis cell lines--model for investigation of host-pathogen interaction in a natural host for emerging viruses
Q34017835Functional characterization of Negri bodies (NBs) in rabies virus-infected cells: Evidence that NBs are sites of viral transcription and replication
Q38525112G gene-deficient single-round rabies viruses for neuronal circuit analysis
Q35111022Heat shock protein 70 regulates degradation of the mumps virus phosphoprotein via the ubiquitin-proteasome pathway
Q39394441Hsp70 protein positively regulates rabies virus infection
Q33921332Human neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling.
Q30619213Human rabies: neuropathogenesis, diagnosis, and management
Q64971795IRF1 Maintains Optimal Constitutive Expression of Antiviral Genes and Regulates the Early Antiviral Response.
Q97553625Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids
Q38654706Immunological aspects of rabies: a literature review
Q58852413Infectious Diseases (esp. Equatorial): Infections of the Nervous System
Q59353657Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice
Q37945180Interferon response and viral evasion by members of the family rhabdoviridae
Q64234190Involvement of Actin-Regulating Factor Cofilin in the Inclusion Body Formation and RNA Synthesis of Human Parainfluenza Virus Type 3 via Interaction With the Nucleoprotein
Q49755954Lab-Attenuated Rabies Virus Causes Abortive Infection and Induces Cytokine Expression in Astrocytes by Activating Mitochondrial Antiviral-Signaling Protein Signaling Pathway.
Q37631200Latent viral infections of the nervous system: role of the host immune response.
Q39263769Membrane and inclusion body targeting of lyssavirus matrix proteins
Q28732060Molecular and cellular aspects of rhabdovirus entry
Q64234842Natural Infection with Rabies Virus: A Histopathological and Immunohistochemical Study of Human Brains
Q40133967Negri bodies are viral factories with properties of liquid organelles
Q37703657Neurons under viral attack: victims or warriors?
Q36559961Neurotropic arboviruses induce interferon regulatory factor 3-mediated neuronal responses that are cytoprotective, interferon independent, and inhibited by Western equine encephalitis virus capsid
Q39808371Peptides that mimic the amino-terminal end of the rabies virus phosphoprotein have antiviral activity
Q42018061Protective role of MyD88-independent innate immune responses against prion infection
Q27314173Protein expression redirects vesicular stomatitis virus RNA synthesis to cytoplasmic inclusions
Q40715034Rabies vaccination at a virus-inoculated site as an alternative option to rabies immunoglobulin
Q33641422Rabies virus infection induces type I interferon production in an IPS-1 dependent manner while dendritic cell activation relies on IFNAR signaling
Q39393526Rabies - epidemiology, pathogenesis, public health concerns and advances in diagnosis and control: a comprehensive review
Q26801290Resistance to Rhabdoviridae Infection and Subversion of Antiviral Responses
Q37960770Reviewing host proteins of Rhabdoviridae: possible leads for lesser studied viruses
Q34299135Secretion of the human Toll-like receptor 3 ectodomain is affected by single nucleotide polymorphisms and regulated by Unc93b1.
Q39166204Systems Biomedicine of Rabies Delineates the Affected Signaling Pathways.
Q41925485TLR3 is required for survival following Coxsackievirus B3 infection by driving T lymphocyte activation and polarization: The role of dendritic cells.
Q36056898The Roles and Perspectives of Toll-Like Receptors and CD4(+) Helper T Cell Subsets in Acute Viral Encephalitis
Q37641016The cell biology of rabies virus: using stealth to reach the brain
Q38969667The chaperonin CCTα is required for efficient transcription and replication of rabies virus
Q36959539The co-chaperone Cdc37 regulates the rabies virus phosphoprotein stability by targeting to Hsp90AA1 machinery
Q89899084The dual role of TLR7 in the pathogenesis of rabies virus in a mouse model
Q35126693The ectodomain of TLR3 receptor is required for its plasma membrane translocation
Q37157195The importance of immune evasion in the pathogenesis of rabies virus.
Q39497376The type I interferon response bridles rabies virus infection and reduces pathogenicity
Q64114489Toll-Like Receptor 7 Enhances Rabies Virus-Induced Humoral Immunity by Facilitating the Formation of Germinal Centers
Q42210295Toll-like receptor 3 inhibits Newcastle disease virus replication through activation of pro-inflammatory cytokines and the type-1 interferon pathway
Q37389400Toll-like receptors 3, 4, and 7 are expressed in the enteric nervous system and dorsal root ganglia
Q38275791Viral capsid assembly as a model for protein aggregation diseases: Active processes catalyzed by cellular assembly machines comprising novel drug targets
Q24294301Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antiviral platform
Q37512235Virus-heat shock protein interaction and a novel axis for innate antiviral immunity
Q53274859[Neuroinflammation: Dr Jekyll or Mr Hyde?].

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