Ire1 mediated mRNA splicing in a C-terminus deletion mutant of Drosophila Xbp1

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Ire1 mediated mRNA splicing in a C-terminus deletion mutant of Drosophila Xbp1 is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9j5588C
P356DOI10.1371/JOURNAL.PONE.0105588
P932PMC publication ID4138184
P698PubMed publication ID25136861
P5875ResearchGate publication ID264861344

P50authorCatarina J GasparQ47135436
Pedro M. DomingosQ47135459
Dina S CoelhoQ59545248
P2860cites workXBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein responseQ38845249
Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA.Q39608147
Ire1 regulated XBP1 mRNA splicing is essential for the unfolded protein response (UPR) in Drosophila melanogasterQ47071152
Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA.Q47942024
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1Q80979487
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans developmentQ24292104
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress responseQ24303865
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cellsQ24309442
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small moleculeQ24596804
The ER stress factor XBP1s prevents amyloid-beta neurotoxicityQ24598012
Unfolded protein response in a Drosophila model for retinal degenerationQ24682908
Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in DrosophilaQ27346679
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
Targeted gene expression as a means of altering cell fates and generating dominant phenotypesQ27861039
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein responseQ27933479
A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein responseQ27938493
Proteasome inhibitors disrupt the unfolded protein response in myeloma cellsQ28155919
The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domainQ28207716
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNAQ28214814
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
The unfolded protein response: from stress pathway to homeostatic regulationQ29547396
Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleusQ29620179
On the mechanism of sensing unfolded protein in the endoplasmic reticulumQ34230593
Messenger RNA targeting to endoplasmic reticulum stress signalling sites.Q34903088
Regulation of sumo mRNA during endoplasmic reticulum stressQ34995137
The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasisQ36314567
Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells.Q36490338
Unfolded protein response in Drosophila: why another model can make it fly.Q36771208
A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila developmentQ36780339
ER stress protects from retinal degenerationQ37194635
Regulated Ire1-dependent decay of messenger RNAs in mammalian cellsQ37309146
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradationQ37359601
Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in DrosophilaQ37381743
The unfolded protein response in secretory cell function.Q38039150
Evolution of the unfolded protein response.Q38078141
Getting RIDD of RNA: IRE1 in cell fate regulationQ38198370
Physiological roles of regulated Ire1 dependent decayQ38209331
The xbp-1 gene is essential for development in DrosophilaQ38305993
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.Q38311676
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
P304page(s)e105588
P577publication date2014-08-19
P1433published inPLOS OneQ564954
P1476titleIre1 mediated mRNA splicing in a C-terminus deletion mutant of Drosophila Xbp1
P478volume9

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cites work (P2860)
Q24701804Apoptosis, autophagy and unfolded protein response pathways in Arbovirus replication and pathogenesis
Q49884225Inositol-Requiring Enzyme 1 Facilitates Diabetic Wound Healing Through Modulating MicroRNAs

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