CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells

scientific article

CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MT.2014.173
P8608Fatcat IDrelease_blsp42ebkfdjjdbxr4fesmdwku
P932PMC publication ID4426797
P698PubMed publication ID25189742
P5875ResearchGate publication ID265377392

P50authorKerstin B KaufmannQ38326220
Hubert ServeQ39186141
P2093author name stringManuel Grez
Tobias Abel
Christian J Buchholz
Sabrina Kneissl
Martijn Brugman
Hana Kunkel
Uta Müller-Kuller
Joachim Schwäble
Linping Chen-Wichmann
Benjamin Goebel
Christian Brendel
Leonid Bystrykh
Abriss Daniela
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Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cellsQ42741832
Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectorsQ42863043
Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor.Q43944919
Novel lentiviral vectors displaying "early-acting cytokines" selectively promote survival and transduction of NOD/SCID repopulating human hematopoietic stem cells.Q44120659
Highly efficient lentiviral gene transfer in CD34+ and CD34+/38-/lin- cells from mobilized peripheral blood after cytokine prestimulationQ44495581
Maximal lentivirus-mediated gene transfer and sustained transgene expression in human hematopoietic primitive cells and their progenyQ44772246
Cytokine-facilitated transduction leads to low-level engraftment in nonablated hostsQ45295243
Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectorsQ45855831
Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient miceQ45866157
Distinct classes of human stem cells that differ in proliferative and self-renewal potentialQ45873643
AC133+ G0 cells from cord blood show a high incidence of long-term culture-initiating cells and a capacity for more than 100 million-fold amplification of colony-forming cells in vitroQ45877579
Gene therapy matures in the clinicQ45880394
Molecular evidence for stem cell function of the slow-dividing fraction among human hematopoietic progenitor cells by genome-wide analysisQ47749134
Cytokines, including stem cell factor alone, enhance lentiviral transduction in nondividing human LTCIC and NOD/SCID repopulating cellsQ48001966
A novel five-transmembrane hematopoietic stem cell antigen: isolation, characterization, and molecular cloningQ48041391
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment.Q50676184
Isolation and characterization of human CD34(-)Lin(-) and CD34(+)Lin(-) hematopoietic stem cells using cell surface markers AC133 and CD7.Q51081344
Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment.Q52005673
Large-scale isolation of CD133+ progenitor cells from G-CSF mobilized peripheral blood stem cells.Q54785700
Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID miceQ67532844
Cell cycle-related changes in repopulating capacity of human mobilized peripheral blood CD34(+) cells in non-obese diabetic/severe combined immune-deficient miceQ77380979
Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human bloodQ77684631
Comparative analysis of proliferative potential and clonogenicity of MACS-immunomagnetic isolated CD34+ and CD133+ blood stem cells derived from a single donorQ80005254
Adherens junction protein nectin-4 is the epithelial receptor for measles virusQ24295305
Foamy virus biology and its application for vector developmentQ26864134
Gene therapy on the moveQ27007012
AC133, a novel marker for human hematopoietic stem and progenitor cellsQ28115893
LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virusQ28118448
Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G(2)/M transit and do not reenter G(0).Q33181506
Transplantation of a combination of CD133+ and CD34+ selected progenitor cells from alternative donorsQ33358178
Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking studyQ33563393
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.Q34356904
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophyQ34356914
Measles virus glycoprotein-based lentiviral targeting vectors that avoid neutralizing antibodiesQ34447329
DARPins: an efficient targeting domain for lentiviral vectorsQ34757199
The replication rate of human hematopoietic stem cells in vivoQ34997694
Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophyQ35011497
Lentiviral vectors displaying modified measles virus gp overcome pre-existing immunity in in vivo-like transduction of human T and B cells.Q36220659
Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice.Q36772601
Measles virus receptorsQ37386883
Lentiviral vectors with measles virus glycoproteins - dream team for gene transfer?Q37425507
Phenotypes of stem cells from diverse originQ37660233
CD133(+) cells isolated from various sources and their role in future clinical perspectivesQ37798837
CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challengesQ38035206
Haematopoietic stem cell differentiation promotes the release of prominin-1/CD133-containing membrane vesicles--a role of the endocytic-exocytic pathwayQ38984604
Transduction of human progenitor hematopoietic stem cells by human immunodeficiency virus type 1-based vectors is cell cycle dependent.Q39550293
RD114 envelope proteins provide an effective and versatile approach to pseudotype lentiviral vectorsQ39650863
A novel lentiviral vector targets gene transfer into human hematopoietic stem cells in marrow from patients with bone marrow failure syndrome and in vivo in humanized mice.Q39683011
Molecular evidence of lentiviral vector-mediated gene transfer into human self-renewing, multi-potent, long-term NOD/SCID repopulating hematopoietic cellsQ40693301
Absence of a relationship between immunophenotypic and colony enumeration analysis of endothelial progenitor cells in clinical haematopoietic cell sourcesQ41944621
P433issue1
P304page(s)63-70
P577publication date2014-09-05
P1433published inMolecular TherapyQ15762400
P1476titleCD133-targeted gene transfer into long-term repopulating hematopoietic stem cells
P478volume23

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cites work (P2860)
Q41899254CD105 is a surface marker for receptor-targeted gene transfer into human long-term repopulating hematopoietic stem cells
Q40228003Chemoprotection of murine hematopoietic cells by combined gene transfer of cytidine deaminase (CDD) and multidrug resistance 1 gene (MDR1).
Q91841922Gene therapy of hematological disorders: current challenges
Q36596865Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease
Q40045829In Vivo Hematopoietic Stem Cell Transduction.
Q37395719Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype
Q38815488Optimizing autologous cell grafts to improve stem cell gene therapy
Q26750586Production of lentiviral vectors
Q38672557Single-cell analyses to reveal hematopoietic stem cell fate decisions

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