DARPins: an efficient targeting domain for lentiviral vectors

scientific article

DARPins: an efficient targeting domain for lentiviral vectors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MT.2010.298
P8608Fatcat IDrelease_oomomfquyjf5hnnrrlyw3mqm4q
P932PMC publication ID3070099
P698PubMed publication ID21224833
P5875ResearchGate publication ID49745663

P50authorMichael D. MühlebachQ60981009
Andreas PlückthunQ23057697
P2093author name stringChristian Jost
Klaus Cichutek
Christian J Buchholz
Robert C Münch
Thomas Schaser
Sabrina Kneissl
P2860cites workImportance of the cytoplasmic tails of the measles virus glycoproteins for fusogenic activity and the generation of recombinant measles virusesQ39684160
Targeting trastuzumab-resistant breast cancer cells with a lentivirus engineered to bind antibodies that recognize HER-2.Q39727268
Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectorsQ42863043
An oncolytic measles virus engineered to enter cells through the CD20 antigenQ45729228
High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoterQ45732758
Lentiviral vector retargeting to P-glycoprotein on metastatic melanoma through intravenous injectionQ46167187
Removal of the conserved disulfide bridges from the scfv fragment of an antibody: effects on folding kinetics and aggregationQ57840042
Designed to be stable: crystal structure of a consensus ankyrin repeat proteinQ24550750
A designed ankyrin repeat protein evolved to picomolar affinity to Her2Q27644627
High-affinity binders selected from designed ankyrin repeat protein librariesQ28257550
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivoQ29616612
The ankyrin repeat: a diversity of interactions on a common structural frameworkQ29616794
Targeting human T cells by retroviral vectors displaying antibody domains selected from a phage display libraryQ30840200
The scFv fragment of the antibody hu4D5-8: evidence for early premature domain interaction in refoldingQ31853054
Efficient selection of DARPins with sub-nanomolar affinities using SRP phage displayQ33360541
Redirecting lentiviral vectors by insertion of integrin-tageting peptides into envelope proteins.Q33711459
A versatile targeting system with lentiviral vectors bearing the biotin-adaptor peptide.Q33711477
Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targetingQ33740415
Receptors and entry cofactors for retroviruses include single and multiple transmembrane-spanning proteins as well as newly described glycophosphatidylinositol-anchored and secreted proteins.Q34010373
Biology of HER2 and its importance in breast cancerQ34428745
The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesisQ34493341
Medicine. A comeback for gene therapyQ34613525
DARPins: a true alternative to antibodies.Q34653885
Gene delivery by lentivirus vectorsQ34688367
Cell entry by measles virus: long hybrid receptors uncouple binding from membrane fusionQ35861422
Affinity thresholds for membrane fusion triggering by viral glycoproteinsQ36315685
Measles virus: cellular receptors, tropism and pathogenesisQ36590422
Strategies for targeting lentiviral vectorsQ37347165
Lentiviral vectors with measles virus glycoproteins - dream team for gene transfer?Q37425507
Novel anticancer targets: revisiting ERBB2 and discovering ERBB3.Q37523202
Targeted cell entry of lentiviral vectorsQ37589994
P433issue4
P304page(s)686-693
P577publication date2011-01-11
P1433published inMolecular TherapyQ15762400
P1476titleDARPins: an efficient targeting domain for lentiviral vectors
P478volume19

Reverse relations

cites work (P2860)
Q30378994A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform.
Q57839812A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors
Q38917869A scalable method to concentrate lentiviral vectors pseudotyped with measles virus glycoproteins
Q59356321A simple strategy for retargeting lentiviral vectors to desired cell types via a disulfide-bond-forming protein-peptide pair
Q34163977Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein
Q41899254CD105 is a surface marker for receptor-targeted gene transfer into human long-term repopulating hematopoietic stem cells
Q35238704CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells
Q42254939CD19 and CD20 targeted vectors induce minimal activation of resting B lymphocytes
Q60948710CD46 Null Packaging Cell Line Improves Measles Lentiviral Vector Production and Gene Delivery to Hematopoietic Stem and Progenitor Cells
Q41877997Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy
Q39199726DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safety
Q45943585Designed Ankyrin Repeat Proteins as Her2 Targeting Domains in Chimeric Antigen Receptor-Engineered T Cells.
Q42541148Displaying high-affinity ligands on adeno-associated viral vectors enables tumor cell-specific and safe gene transfer
Q36777139Enhanced lysis by bispecific oncolytic measles viruses simultaneously using HER2/neu or EpCAM as target receptors
Q40562689In Vivo Gene Delivery to Lymph Node Stromal Cells Leads to Transgene-specific CD8+ T Cell Anergy in Mice.
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Q37358531Specific targeting of human interleukin (IL)-13 receptor α2-positive cells with lentiviral vectors displaying IL-13.
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